Larry Culpepper, MD

Professor, Family Medicine

Larry Culpepper


Dr. Culpepper, Professor of Family Medicine, was the founding Chairman of the Department. He received his M.D from Baylor College of Medicine and his M.P.H. from Boston University. He has served as President of the North American Primary Care Group (NAPCRG), Chairman of the Research Committee of the Society of Teachers of Family Medicine (STFM), and is the Chairman of the Board of Rhode Island Public Health Foundation. He is a Primary Care Fellow of the Federal Health Resources and Services Administration, and has chaired or served as a member of research grant review committees for 5 NIH and other federal agencies. He has received the STFM Excellence in Education, the STFM-NAPCRG Hames Research awards, and the Maurice Wood Award for Lifetime Contribution to Primary Care Research (2010) and was elected to the Institute of Medicine in 1998. The BU School of Public Health recognized him with its 2008 BUSPH Distinguished Alumni Award. He has conducted research in otitis media, and school-based and community interventions to improve pregnancy outcomes and to prevent teen pregnancies and has been the principal investigator of an AHRQ funded center for patient safety research devoted to low income and minority vulnerable populations in ambulatory care settings, principal investigator of interventions to improve the care of uninsured patients and urban patients with diabetes and depression, co-principal investigator of a study to decrease delays in CHC patient follow-up for abnormal mammography, and co-investigator of a long term study of the course of anxiety disorders in primary care settings. Dr Culpepper co-chaired a panel on Otitis Media with Effusion for the American Academy of Family Physicians, the American Academy of Pediatrics, and the American Academy of Otolaryngology-Head and Neck Surgery, and is a member of the AAP-AAFP panel on acute otitis media. He founded and chaired the board of the Rhode Island Public Health Foundation (1992-2011). He is a member of The Depression and Bipolar Support Alliance and the Anxiety Disorders Association of America Scientific Advisory Boards. He currently is the primary care member of an Institute of Medicine Committee on the Assessment of Ongoing Efforts in the Treatment of PTSD (2011-15). He was the initial family medicine editor of UpToDate and is the editor of the Journal of Clinical Psychiatry Primary Care Companion.


  • Baylor University, MD
  • Boston University, MPH
  • Baylor University, BS


  • Published on 3/11/2024

    Culpepper L, Martin A, Nabulsi N, Parikh M. The Humanistic and Economic Burden Associated with Major Depressive Disorder: A Retrospective Cross-Sectional Analysis. Adv Ther. 2024 Mar 11. PMID: 38466558.

    Read at: PubMed
  • Published on 2/28/2023

    Culpepper L. The PCC Is 25 Years Strong: A Message From the Editor. Prim Care Companion CNS Disord. 2023 Feb 28; 25(1). PMID: 36898025.

    Read at: PubMed
  • Published on 5/12/2022

    Culpepper L, Vieta E, Kelly DL, Patel MD, Szatmári B, Hankinson A, Earley WR. Minimal Effects of Cariprazine on Prolactin Levels in Bipolar Disorder and Schizophrenia. Neuropsychiatr Dis Treat. 2022; 18:995-1011. PMID: 35591886.

    Read at: PubMed
  • Published on 5/1/2022

    Mitchell SE, Reichert M, Howard JM, Krizman K, Bragg A, Huffaker M, Parker K, Cawley M, Roberts HW, Sung Y, Brown J, Culpepper L, Cabral HJ, Jack BW. Reducing Readmission of Hospitalized Patients With Depressive Symptoms: A Randomized Trial. Ann Fam Med. 2022 May-Jun; 20(3):246-254. PMID: 35606137.

    Read at: PubMed
  • Published on 4/1/2022

    Culpepper L, Krystal AD, Pinner K, Moline M. Post Hoc Analysis of the Impact of Lemborexant on Patient-Reported Sleep and Insomnia Severity in Adults with Insomnia and Depression Histories. CNS Spectr. 2022 Apr; 27(2):243. PMID: 35477633.

    Read at: PubMed
  • Published on 2/24/2022

    Culpepper L. New Insights Into COVID-19 and Gratitude for Service. Prim Care Companion CNS Disord. 2022 Feb 24; 24(1). PMID: 35213941.

    Read at: PubMed
  • Published on 7/22/2021

    Culpepper L. Notice of Duplicate Publication. Prim Care Companion CNS Disord. 2021 Jul 22; 23(4). PMID: 34297489.

    Read at: PubMed
  • Published on 2/24/2021

    Culpepper L. Informing Our Response to 3 Pandemics. Prim Care Companion CNS Disord. 2021 02 24; 23(1). PMID: 34000120.

    Read at: PubMed
  • Published on 2/5/2021

    Joyce C, Roseen EJ, Keysor JJ, Gross KD, Culpepper L, Saper RB. Can Yoga or Physical Therapy for Chronic Low Back Pain Improve Depression and Anxiety Among Adults From a Racially Diverse, Low-Income Community? A Secondary Analysis of a Randomized Controlled Trial. Arch Phys Med Rehabil. 2021 06; 102(6):1049-1058. PMID: 33556352.

    Read at: PubMed
  • Published on 1/14/2021

    Hong RH, Murphy JK, Michalak EE, Chakrabarty T, Wang Z, Parikh SV, Culpepper L, Yatham LN, Lam RW, Chen J. Implementing Measurement-Based Care for Depression: Practical Solutions for Psychiatrists and Primary Care Physicians. Neuropsychiatr Dis Treat. 2021; 17:79-90. PMID: 33469295.

    Read at: PubMed

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