Kieran Sheahan, MD
Adjunct Assistant Professor, Pathology & Laboratory Medicine
Biography
Professor Kieran Sheahan: MB,BCh,.BAO B.Sc. M.R.C.P.I. F.R.C.P.I. F.F.Path .F.R.C.Path. is a Consultant Histopathologist & Head of Histopathology at the Department of Pathology, St. Vincent’s University Hospital, Dublin & Full Clinical Professor, University College Dublin School of Medicine. He graduated from UCD Medical School in 1981 & trained in the Anatomic Pathology Program, Mallory Institute of Pathology, Boston, where he was Assistant Professor of Pathology, Boston University until 1992. He took up his present appointment in 1992, became Associate Clinical Professor, UCD School of Medicine in 2007 & Full Clinical Professor in 2014. He is a Director of the Centre for Colorectal Disease , SVUH. He is currently Director of Education & Training, Faculty of Pathology, Royal College of Physicians of Ireland & a member of the working group of the National QA programme in Histopathology.
He is a former Board Member of National Cancer Registry & former President of the Pathology Section, RAMI . He was the founding Treasurer and is a former President of the Irish Society of Surgical Pathology. His research interests include Prognostic & predictive markers in colorectal cancer, familial gastrointestinal cancer, application of immunohistochemical & molecular genetic techniques in cancer & the pathobiology of inflammatory bowel disease. He has over 140 original publications in peer-reviewed biomedical journals and has authored numerous reviews & book chapters.
Education
- University College Dublin (UCD), MBBCh
- University College Dublin (UCD), BAO
- University College Dublin (UCD), BSc
Publications
- Published on 9/22/2021
Elsayed I, Li L, Sheahan K, Moran B, Bakheit S, Wang X. Adenoma to carcinoma: A portrait of molecular and immunological profiles of colorectal sporadic tumors. Int Immunopharmacol. 2021 Nov; 100:108168. PMID: 34562842.
Read at: PubMed - Published on 7/17/2021
Tsekrekos A, Vieth M, Ndegwa N, Bateman A, Flejou JF, Grabsch HI, Mastracci L, Meijer SL, Saragoni L, Sheahan K, Shetye J, Yantiss R, Lundell L, Detlefsen S. Interobserver agreement of a gastric adenocarcinoma tumor regression grading system that incorporates assessment of lymph nodes. Hum Pathol. 2021 10; 116:94-101. PMID: 34284051.
Read at: PubMed - Published on 3/1/2021
Haddad TS, Lugli A, Aherne S, Barresi V, Terris B, Bokhorst JM, Brockmoeller SF, Cuatrecasas M, Simmer F, El-Zimaity H, Fléjou JF, Gibbons D, Cathomas G, Kirsch R, Kuhlmann TP, Langner C, Loughrey MB, Riddell R, Ristimäki A, Kakar S, Sheahan K, Treanor D, van der Laak J, Vieth M, Zlobec I, Nagtegaal ID. Improving tumor budding reporting in colorectal cancer: a Delphi consensus study. Virchows Arch. 2021 Sep; 479(3):459-469. PMID: 33650042.
Read at: PubMed - Published on 11/19/2020
Saliba G, Detlefsen S, Carneiro F, Conner J, Dorer R, Fléjou JF, Hahn H, Kamaradova K, Mastracci L, Meijer SL, Sabo E, Sheahan K, Riddell R, Wang N, Yantiss RK, Lundell L, Low D, Vieth M, Klevebro F. Tumor regression grading after neoadjuvant treatment of esophageal and gastroesophageal junction adenocarcinoma: results of an international Delphi consensus survey. Hum Pathol. 2021 02; 108:60-67. PMID: 33221343.
Read at: PubMed - Published on 10/12/2020
O'Byrne LM, Witherspoon J, Verhage RJJ, O'Brien M, Muldoon C, Ryan C, Buckley M, Murphy T, Reynolds R, Patchett S, Kay E, Azam H, Robb W, Arumugasamy M, Mathuna PM, Leyden J, Gargan S, Doherty G, Sheahan K, Collins C, Nath A, O'Sullivan J, Donohoe CL, Ravi N, O'Toole D, Reynolds JV. Barrett's Registry Collaboration of academic centers in Ireland reveals high progression rate of low-grade dysplasia and low risk from nondysplastic Barrett's esophagus: report of the RIBBON network. Dis Esophagus. 2020 Oct 12; 33(10). PMID: 32193532.
Read at: PubMed - Published on 5/13/2020
Roseweir AK, Park JH, Hoorn ST, Powell AG, Aherne S, Roxburgh CS, McMillan DC, Horgan PG, Ryan E, Sheahan K, Vermeulen L, Paul J, Harkin A, Graham J, Sansom O, Church DN, Tomlinson I, Saunders M, Iveson TJ, Edwards J. Histological phenotypic subtypes predict recurrence risk and response to adjuvant chemotherapy in patients with stage III colorectal cancer. J Pathol Clin Res. 2020 10; 6(4):283-296. PMID: 32401426.
Read at: PubMed - Published on 4/18/2020
Dunne MR, Phelan JJ, Michielsen AJ, Maguire AA, Dunne C, Martin P, Noonan S, Tosetto M, Geraghty R, Fennelly D, Sheahan K, Ryan EJ, O'Sullivan J. Characterising the prognostic potential of HLA-DR during colorectal cancer development. Cancer Immunol Immunother. 2020 Aug; 69(8):1577-1588. PMID: 32306077.
Read at: PubMed - Published on 12/17/2019
Lindner AU, Resler AJ, Carberry S, Oficjalska K, Bacon O, Lee CS, Choudhry A, Burke JP, Sheahan K, Cremona M, Hennessy BT, McNamara D, Doherty G, Ryan EJ, Prehn JHM. Systems biology analysis identifies molecular determinants of chemotherapy-induced diarrhoea. J Mol Med (Berl). 2020 01; 98(1):149-159. PMID: 31848663.
Read at: PubMed - Published on 8/9/2019
Caiazza F, Oficjalska K, Tosetto M, Phelan JJ, Noonan S, Martin P, Killick K, Breen L, O'Neill F, Nolan B, Furney S, Power R, Fennelly D, Craik CS, O'Sullivan J, Sheahan K, Doherty GA, Ryan EJ. KH-Type Splicing Regulatory Protein Controls Colorectal Cancer Cell Growth and Modulates the Tumor Microenvironment. Am J Pathol. 2019 10; 189(10):1916-1932. PMID: 31404541.
Read at: PubMed - Published on 9/12/2018
Tsekrekos A, Detlefsen S, Riddell R, Conner J, Mastracci L, Sheahan K, Shetye J, Lundell L, Vieth M. Histopathologic tumor regression grading in patients with gastric carcinoma submitted to neoadjuvant treatment: results of a Delphi survey. Hum Pathol. 2019 02; 84:26-34. PMID: 30217622.
Read at: PubMed
View 46 more publications: View full profile at BUMC