Keith Tornheim, PhD

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Keith Tornheim, PhD, began his career at the Chobanian and Avedisian School of Medicine in 1981 as an assistant professor. Since then he has published over fifty articles, mainly on the topic of metabolism. He originally studied spontaneous oscillatory behavior of glycolysis in muscle extracts. Dr. Tornheim is currently in the Biochemistry teaching mission, teaching metabolism to first-year medical, dental and graduate students.

Publications

  • Published 7/15/2012

    Martínez-Costa OH, Sánchez V, Lázaro A, Hernández ED, Tornheim K, Aragón JJ. Distinct functional roles of the two terminal halves of eukaryotic phosphofructokinase. Biochem J. 2012 Jul 15; 445(2):213-8. PMID: 22530721.

    Read at: PubMed

  • Published 11/10/2009

    Haller JF, Smith C, Liu D, Zheng H, Tornheim K, Han GS, Carman GM, Zoeller RA. Isolation of novel animal cell lines defective in glycerolipid biosynthesis reveals mutations in glucose-6-phosphate isomerase. J Biol Chem. 2010 Jan 8; 285(2):866-77. PMID: 19903819.

    Read at: PubMed

  • Published 9/24/2009

    Getty-Kaushik L, Viereck JC, Goodman JM, Guo Z, LeBrasseur NK, Richard AM, Flanagan JN, Yaney GC, Hamilton JA, Tornheim K. Mice deficient in phosphofructokinase-M have greatly decreased fat stores. Obesity (Silver Spring). 2010 Mar; 18(3):434-40. PMID: 19779479.

    Read at: PubMed

  • Published 6/26/2007

    Richard AM, Webb DL, Goodman JM, Schultz V, Flanagan JN, Getty-Kaushik L, Deeney JT, Yaney GC, Dunaway GA, Berggren PO, Tornheim K. Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter: impairment in insulin secretion. Am J Physiol Endocrinol Metab. 2007 Sep; 293(3):E794-801. PMID: 17595219.

    Read at: PubMed

  • Published 4/1/2007

    Heart E, Yaney GC, Corkey RF, Schultz V, Luc E, Liu L, Deeney JT, Shirihai O, Tornheim K, Smith PJ, Corkey BE. Ca2+, NAD(P)H and membrane potential changes in pancreatic beta-cells by methyl succinate: comparison with glucose. Biochem J. 2007 Apr 1; 403(1):197-205. PMID: 17181533.

    Read at: PubMed

Other Positions

  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Websites

Education

  • Brandeis University, PhD
  • Antioch College, BS