Katherine Anne Gifford, PsyD
Associate Professor, Anatomy & Neurobiology

Biography
Dr. Katherine Gifford is a clinical neuropsychologist and an Associate Professor in the Department of Anatomy & Neurobiology at Boston University Chobanian & Avedisian School of Medicine. She is a Investigator within the Precision Brain Health Initiative (https://www.bumc.bu.edu/pbhi/) and the Framingham Heart Study- Brain Aging Program. Dr. Gifford’s research focuses on disorders of aging, dementia, and developing tools for early detection of cognitive impairment. Her research incudes a specific emphasis on understanding subjective cognitive decline in older adults, or when people start to notice changes in their own memory and thinking. She is involved in independent and collaborative research projects that improve early identification of unhealthy aging, clinical phenotyping of abnormal brain aging (i.e., Alzheimer’s disease and related disorder), and health care education to improve primary care management of dementias.
Before joining the BUSM faculty, she was an Associate Professor (tenured) of Neurology at Vanderbilt University Medical Center, Co-Director of the Vanderbilt Sports Concussion Center, and Clinical Core Co-Leader of the Vanderbilt Exploratory Alzheimer’s Disease Center. She obtained her bachelor’s degree in psychology at Skidmore College in Saratoga Springs, NY and her doctoral degree in clinical psychology from the Florida Institute of Technology in Melbourne, FL. She completed her pre-doctoral internship in neuropsychology at the Henry Ford Health System in Detroit, MI. Her postdoctoral fellowship in neuropsychology was completed at Boston University and at Vanderbilt University.
Education
- Florida Institute of Technology, PsyD
- Florida Institute of Technology, MS
- Skidmore College, BA
Publications
- Published on 2/22/2025
Kuhn E, Klinger HM, Amariglio RE, Wagner M, Jessen F, Düzel E, Heneka MT, Chételat G, Rentz DM, Sperling RA, Ebenau JL, Butterbrod E, Van Der Flier WM, Sikkes SAM, Teunnissen CE, Van Harten AC, Van De Giessen EM, Rami L, Tort A, Sánchez Benavides G, Gifford KA, Van Hulle C, Buckley RF. SCD-plus features and AD biomarkers in cognitively unimpaired samples: A meta-analytic approach for nine cohort studies. Alzheimers Dement. 2025 Feb 22. PMID: 39985404.
Read at: PubMed - Published on 1/7/2025
Durant A, Mukherjee S, Lee ML, Choi SE, Scollard P, Klinedinst BS, Trittschuh EH, Mez J, Farrer LA, Gifford KA, Cruchaga C, Hassenstab J, Naj AC, Wang LS, Johnson SC, Engelman CD, Kukull WA, Keene CD, Saykin AJ, Cuccaro ML, Kunkle BW, Pericak-Vance MA, Martin ER, Bennett DA, Barnes LL, Schneider JA, Bush WS, Haines JL, Mayeux R, Vardarajan BN, Albert MS, Thompson PM, Jefferson AL, Crane PK, Dumitrescu L, Archer DB, Hohman TJ, Gaynor LS. Evaluating the association of APOE genotype and cognitive resilience in SuperAgers. medRxiv. 2025 Jan 07. PMID: 39830268.
Read at: PubMed - Published on 1/6/2025
Kang K, Zhang P, Dumitrescu L, Mukherjee S, Lee ML, Choi SE, Trittschuh EH, Mez J, Saykin AJ, Gifford KA, Buckley RF, Gao X, Di J, Crane PK, Hohman TJ, Liu D. The Dynamics of Cognitive Decline towards Alzheimer's Disease Progression: Results from ADSP-PHC's Harmonized Cognitive Composites. medRxiv. 2025 Jan 06. PMID: 39830238.
Read at: PubMed - Published on 1/2/2025
Seto M, Clifton M, Gomez ML, Coughlan G, Gifford KA, Jefferson AL, De Jager PL, Bennett DA, Wang Y, Barnes LL, Schneider JA, Hohman TJ, Buckley RF, Dumitrescu L. Sex-specific Associations of Gene Expression with Alzheimer's Disease Neuropathology and Ante-mortem Cognitive Performance. bioRxiv. 2025 Jan 02. PMID: 39803447.
Read at: PubMed - Published on 12/25/2024
Winfree RL, Nolan E, Blennow K, Zetterberg H, Gifford KA, Pechman KR, Schneider J, Bennett DA, Petyuk VA, Jefferson AL, Hohman TJ. Vascular endothelial growth factor receptor-1 (FLT1) interactions with amyloid-beta in Alzheimer's disease: A putative biomarker of amyloid-induced vascular damage. Neurobiol Aging. 2025 Mar; 147:141-149. PMID: 39752902.
Read at: PubMed - Published on 12/22/2024
Peterson A, Sathe A, Zaras D, Yang Y, Durant A, Deters KD, Shashikumar N, Pechman KR, Kim ME, Gao C, Mohd Khairi N, Li Z, Yao T, Huo Y, Dumitrescu L, Gifford KA, Wilson JE, Cambronero FE, Risacher SL, Beason-Held LL, An Y, Arfanakis K, Erus G, Davatzikos C, Tosun D, Toga AW, Thompson PM, Mormino EC, Habes M, Wang D, Zhang P, Schilling K, Albert M, Kukull W, Biber SA, Landman BA, Johnson SC, Schneider J, Barnes LL, Bennett DA, Jefferson AL, Resnick SM, Saykin AJ, Hohman TJ, Archer DB. Sex and APOE e4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer's disease. Alzheimers Dement. 2025 Jan; 21(1):e14343. PMID: 39711105.
Read at: PubMed - Published on 12/20/2024
Bolton CJ, Steinbach M, Khan OA, Liu D, O'Malley J, Dumitrescu L, Peterson A, Jefferson AL, Hohman TJ, Zetterberg H, Gifford KA. Clinical and demographic factors modify the association between plasma phosphorylated tau-181 and cognition. Alzheimers Dement (Amst). 2024; 16(4):e70047. PMID: 39713247.
Read at: PubMed - Published on 11/18/2024
Ding H, Gifford K, Shih LC, Ho K, Rahman S, Igwe A, Low S, Popp Z, Searls E, Li Z, Madan S, Burk A, Hwang PH, Anda-Duran I, Kolachalama VB, Au R, Lin H. Exploring the Perspectives of Older Adults on a Digital Brain Health Platform Using Natural Language Processing: Cohort Study. JMIR Form Res. 2024 Nov 18; 8:e60453. PMID: 39556805.
Read at: PubMed - Published on 10/25/2024
Ding H, Ho K, Searls E, Low S, Li Z, Rahman S, Madan S, Igwe A, Popp Z, Burk A, Wu H, Ding Y, Hwang PH, Anda-Duran I, Kolachalama VB, Gifford KA, Shih LC, Au R, Lin H. Assessment of Wearable Device Adherence for Monitoring Physical Activity in Older Adults: Pilot Cohort Study. JMIR Aging. 2024 Oct 25; 7:e60209. PMID: 39454101.
Read at: PubMed - Published on 10/23/2024
Bolton CJ, Khan OA, Liu D, Wilhoite S, Dumitrescu L, Peterson A, Blennow K, Zetterberg H, Hohman TJ, Jefferson AL, Gifford KA. Cognitive status and demographics modify the association between subjective cognition and amyloid. Ann Clin Transl Neurol. 2024 Nov; 11(11):2977-2986. PMID: 39440670.
Read at: PubMed
View 79 more publications: View full profile at BUMC