Jonathan S. Williams, MD

Adjunct Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Williams is Associate Professor of Medicine at Harvard Medical School and practicing endocrinologist at Brigham and Women's Hospital and the Boston VA Healthcare System. He directs the Cardiometabolic Human Genetics Research Program, which houses the HyperPath and HyperPath2 cohorts established over 20 years ago as a multinational program to decipher the genetic and mechanistic underpinnings of complex heritable diseases. His administrative roles include IRB Chair (MassGeneral Brigham), Co-Director Clinical and Translational Research Academy (Harvard Medical School), and Lead Medical Research Officer, Center for Clinical Investigations (Brigham and Women's Hospital).

Publications

  • Published 8/18/2026

    Heydarpour M, Gholami S, Karimian M, Lau TQ, Lee JKX, Uddin R, Pojoga LH, Williams GH, Williams JS. Regulatory Variant of Klotho (rs9563124) Associates with Ang-II Stimulated Aldosterone and Salt Sensitive Blood Pressure. J Clin Endocrinol Metab. 2026 Aug 18. PMID: 42610461.

    Read at: PubMed

  • Published 8/12/2026

    Yuan YE, Adler GK, Rosner B, Merino AA, Guzelce EC, Williams GH, Williams JS, Haas AV. Investigating a Mineralocorticoid Receptor Mediation of an Ultra-Short Feedback Loop Regulating Aldosterone Production in Humans. Clin Endocrinol (Oxf). 2026 Dec; 105(6):610-615. PMID: 42581762.

    Read at: PubMed

  • Published 6/30/2026

    Yuan YE, Porter LM, Haas AV, Hornik ES, Koefoed AW, Easly-Merski R, Murray G, Farah S, Adler GK, Williams JS. The impact of statins on aldosterone production in healthy adults: a randomized controlled study. J Endocr Soc. 2026 Jul; 10(7):bvag141. PMID: 42404178.

    Read at: PubMed

  • Published 1/27/2026

    Zitting KM, Gilmore KR, Lockyer BJ, Leary EB, Wang W, Issa NC, Quan SF, Williams JS, Duffy JF, Czeisler CA. Solriamfetol for Excessive Sleepiness in Early-Morning Shift Work Disorder. NEJM Evid. 2026 Feb; 5(2):EVIDoa2500190. PMID: 41590992.

    Read at: PubMed

  • Published 12/30/2025

    Tchio C, Maher M, Moth C, Meiler J, Lane JM, Taylor HA, Williams JS, Saxena R. Circadian ADCY3 Ser107Pro variant bridges difficulty awakening in the morning and adiposity. iScience. 2026 Feb 20; 29(2):114587. PMID: 41630919.

    Read at: PubMed

View All 99 Publications:   View Full Profile in BUMC

Other Positions

  • Associate Professor
    Harvard Medical School

Websites

Education

  • Hahnemann University, MD
  • Harvard University, MMS/MMSc
  • Brigham Young University, BS

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