Jonathan S. Williams, MD

Adjunct Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Williams is Associate Professor of Medicine at Harvard Medical School and practicing endocrinologist at Brigham and Women's Hospital and the Boston VA Healthcare System. He directs the Cardiometabolic Human Genetics Research Program, which houses the HyperPath and HyperPath2 cohorts established over 20 years ago as a multinational program to decipher the genetic and mechanistic underpinnings of complex heritable diseases. His administrative roles include IRB Chair (MassGeneral Brigham), Co-Director Clinical and Translational Research Academy (Harvard Medical School), and Lead Medical Research Officer, Center for Clinical Investigations (Brigham and Women's Hospital).

Publications

  • Published 2/27/2025

    Haas AV, Uddin R, Ngu H, Porter L, Heydarpour M, Parksook WW, Pojoga L, Williams JS. Salt Sensitivity of Blood Pressure in Black Individuals with Striatin and Lysine Specific Demethylase-1 Risk Alleles. J Clin Endocrinol Metab. 2025 Feb 27. PMID: 40036637.

    Read at: PubMed

  • Published 12/19/2024

    Caliskan Guzelce E, Wong KYH, Heydarpour M, Pojoga LH, Romero J, Williams JS, Adler GK, Seely EW, Williams GH. Increased Salt Sensitive Blood Pressure in Women Versus men: Is Relative Hyperaldosteronism the Mechanism? J Clin Endocrinol Metab. 2024 Dec 19. PMID: 39700455.

    Read at: PubMed

  • Published 12/18/2024

    Heydarpour M, Parksook WW, Pojoga LH, Williams GH, Williams JS. Mineralocorticoid Receptor and Aldosterone: Interaction Between NR3C2 Genetic Variants, Sex, and Age in a Mixed Cohort. J Clin Endocrinol Metab. 2024 Dec 18; 110(1):e140-e149. PMID: 38437868.

    Read at: PubMed

  • Published 9/11/2024

    Tchio C, Heydarpour M, Pojoga L, Taylor H, Williams G, Williams JS, Seely EW. AGTR1 variant rs2638355 is associated with increased salt sensitivity of blood pressure: a female-specific effect in individuals from the HyperPath cohort. J Hypertens. 2024 Dec 01; 42(12):2180-2186. PMID: 39288250.

    Read at: PubMed

  • Published 3/18/2024

    Aljaibeji H, Heydarpour M, Stanton AM, Williams JS, Pojoga LH, Romero JR, Williams GH. Role of Raptor Gene Variants in Hypertension: Influence on Blood Pressure Independent of Salt Intake in White Population. Hypertension. 2024 May; 81(5):1167-1177. PMID: 38497230.

    Read at: PubMed

Other Positions

  • Associate Professor
    Harvard Medical School

Education

  • Hahnemann University, MD
  • Harvard University, MMS/MMSc
  • Brigham Young University, BS