Jonathan S. Williams, MD

Adjunct Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Williams is Associate Professor of Medicine at Harvard Medical School and practicing endocrinologist at Brigham and Women's Hospital and the Boston VA Healthcare System. He directs the Cardiometabolic Human Genetics Research Program, which houses the HyperPath and HyperPath2 cohorts established over 20 years ago as a multinational program to decipher the genetic and mechanistic underpinnings of complex heritable diseases. His administrative roles include IRB Chair (MassGeneral Brigham), Co-Director Clinical and Translational Research Academy (Harvard Medical School), and Lead Medical Research Officer, Center for Clinical Investigations (Brigham and Women's Hospital).

Publications

  • Published 1/27/2026

    Zitting KM, Gilmore KR, Lockyer BJ, Leary EB, Wang W, Issa NC, Quan SF, Williams JS, Duffy JF, Czeisler CA. Solriamfetol for Excessive Sleepiness in Early-Morning Shift Work Disorder. NEJM Evid. 2026 Feb; 5(2):EVIDoa2500190. PMID: 41590992.

    Read at: PubMed

  • Published 12/30/2025

    Tchio C, Maher M, Moth C, Meiler J, Lane JM, Taylor HA, Williams JS, Saxena R. Circadian ADCY3 Ser107Pro variant bridges difficulty awakening in the morning and adiposity. iScience. 2026 Feb 20; 29(2):114587. PMID: 41630919.

    Read at: PubMed

  • Published 10/16/2025

    Haas AV, Uddin R, Ngu H, Porter L, Heydarpour M, Parksook WW, Pojoga L, Williams JS. Salt Sensitivity of Blood Pressure in Black Individuals With Striatin and Lysine-specific Demethylase-1 Risk Alleles. J Clin Endocrinol Metab. 2025 Oct 16; 110(11):e3803-e3809. PMID: 40036637.

    Read at: PubMed

  • Published 8/7/2025

    Caliskan Guzelce E, Wong KYH, Heydarpour M, Pojoga LH, Romero J, Williams JS, Adler GK, Seely EW, Williams GH. Increased Salt-Sensitive Blood Pressure in Women vs Men: Is Relative Hyperaldosteronism the Mechanism? J Clin Endocrinol Metab. 2025 Aug 07; 110(9):2623-2630. PMID: 39700455.

    Read at: PubMed

  • Published 6/6/2025

    Parisien-La Salle S, Heydarpour M, Tsai CH, Brown JM, Newman AJ, Mahrokhian S, Hanna I, Honzel B, Tsai LC, Waikar S, Inoue K, Zennaro MC, Auchus R, Turcu AF, Williams JS, Sacks B, Moussa M, Vaidya A. The Evolution of Primary Aldosteronism and the Role of Norrin. medRxiv. 2025 Jun 06. PMID: 40502598.

    Read at: PubMed

View All 96 Publications:   View Full Profile in BUMC

Other Positions

  • Associate Professor
    Harvard Medical School

Websites

Education

  • Hahnemann University, MD
  • Harvard University, MMS/MMSc
  • Brigham Young University, BS

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