Jonathan S. Williams, MD

Adjunct Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Williams is Associate Professor of Medicine at Harvard Medical School and practicing endocrinologist at Brigham and Women's Hospital and the Boston VA Healthcare System. He directs the Cardiometabolic Human Genetics Research Program, which houses the HyperPath and HyperPath2 cohorts established over 20 years ago as a multinational program to decipher the genetic and mechanistic underpinnings of complex heritable diseases. His administrative roles include IRB Chair (MassGeneral Brigham), Co-Director Clinical and Translational Research Academy (Harvard Medical School), and Lead Medical Research Officer, Center for Clinical Investigations (Brigham and Women's Hospital).

Publications

  • Published 10/16/2025

    Haas AV, Uddin R, Ngu H, Porter L, Heydarpour M, Parksook WW, Pojoga L, Williams JS. Salt Sensitivity of Blood Pressure in Black Individuals With Striatin and Lysine-specific Demethylase-1 Risk Alleles. J Clin Endocrinol Metab. 2025 Oct 16; 110(11):e3803-e3809. PMID: 40036637.

    Read at: PubMed

  • Published 8/7/2025

    Caliskan Guzelce E, Wong KYH, Heydarpour M, Pojoga LH, Romero J, Williams JS, Adler GK, Seely EW, Williams GH. Increased Salt-Sensitive Blood Pressure in Women vs Men: Is Relative Hyperaldosteronism the Mechanism? J Clin Endocrinol Metab. 2025 Aug 07; 110(9):2623-2630. PMID: 39700455.

    Read at: PubMed

  • Published 6/6/2025

    Parisien-La Salle S, Heydarpour M, Tsai CH, Brown JM, Newman AJ, Mahrokhian S, Hanna I, Honzel B, Tsai LC, Waikar S, Inoue K, Zennaro MC, Auchus R, Turcu AF, Williams JS, Sacks B, Moussa M, Vaidya A. The Evolution of Primary Aldosteronism and the Role of Norrin. medRxiv. 2025 Jun 06. PMID: 40502598.

    Read at: PubMed

  • Published 5/18/2025

    Tchio C, Williams JS, Taylor H, Ollila HM, Saxena R. An integrative approach prioritizes the orphan GPR61 genomic region in tissue-specific regulation of chronotype. Sleep Adv. 2025 Apr; 6(2):zpaf030. PMID: 40612388.

    Read at: PubMed

  • Published 12/18/2024

    Heydarpour M, Parksook WW, Pojoga LH, Williams GH, Williams JS. Mineralocorticoid Receptor and Aldosterone: Interaction Between NR3C2 Genetic Variants, Sex, and Age in a Mixed Cohort. J Clin Endocrinol Metab. 2024 Dec 18; 110(1):e140-e149. PMID: 38437868.

    Read at: PubMed

View All 94 Publications:   View Full Profile in BUMC

Other Positions

  • Associate Professor
    Harvard Medical School

Websites

Education

  • Hahnemann University, MD
  • Harvard University, MMS/MMSc
  • Brigham Young University, BS

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