John H. Connor, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

My laboratory studies the virus-host interaction. We take a variety of approaches from genetic to systems biology to biochemistry and molecular biology. We are studying how viruses take over the cellular protein synthesis apparatus, how cells effectively fight virus infection, and how the host responds to infection with viruses that cause hemorrhagic fever.

Publications

  • Published 1/27/2025

    Nguyen MA, Williams C, Gard AL, Connor JH. Endothelial growth media components alter SARS-CoV-2 spike-directed growth kinetics. J Virol Methods. 2025 Apr; 333:115111. PMID: 39880099.

    Read at: PubMed

  • Published 1/16/2025

    Lin H, Seitz S, Tan Y, Lugagne JB, Wang L, Ding G, He H, Rauwolf TJ, Dunlop MJ, Connor JH, Porco JA, Tian L, Cheng JX. Label-free nanoscopy of cell metabolism by ultrasensitive reweighted visible stimulated Raman scattering. Nat Methods. 2025 Jan 16. PMID: 39820753.

    Read at: PubMed

  • Published 8/6/2024

    Keiser PT, Zhang W, Ricca M, Wacquiez A, Grimins A, Cencic R, Patten JJ, Shah P, Padilha E, Connor JH, Pelletier J, Lyons SM, Saeed M, Brown LE, Porco JA, Davey RA. Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis. Antiviral Res. 2024 Oct; 230:105976. PMID: 39117283.

    Read at: PubMed

  • Published 7/1/2024

    Ross SJ, Hume AJ, Olejnik J, Turcinovic J, Honko AN, McKay LGA, Connor JH, Griffiths A, Mühlberger E, Cifuentes D. Low-Input, High-Resolution 5' Terminal Filovirus RNA Sequencing with ViBE-Seq. Viruses. 2024 Jul 01; 16(7). PMID: 39066227.

    Read at: PubMed

  • Published 5/23/2024

    Hume AJ, Deeney DJ, Smetana JS, Turcinovic J, Connor JH, Belfort M, Mühlberger E, Lennon CW. Improved protein splicing through viral passaging. mBio. 2024 Jun 12; 15(6):e0098424. PMID: 38780266.

    Read at: PubMed

View All 151 Publications:   View Full Profile in BUMC

Other Positions

  • Faculty, National Emerging Infectious Disease Lab
    Boston University
  • Member, Genome Science Institute
    Boston University
  • Member, Bioinformatics Graduate Program
    Boston University
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Websites

Education

  • Duke University, PhD
  • Swarthmore College, BA

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