Jingzhou Zhang, MD MPH

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Zhang is a clinician-investigator specializing in pulmonary and critical care medicine, with a research focus on integrating traditional epidemiologic methods with bioinformatics and multi-omics approaches to improve risk prediction and elucidate the pathobiology of COPD and other chronic lung diseases. He conducts epidemiologic research through the Framingham Heart Study and the COPDGene Study and collaborates with other cohorts within the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program. His current research interests include: 1) Identifying obesity- and body composition-related determinants of COPD risk and heterogeneity, including cardiovascular outcomes; and 2) Defining lung and liver disease risk and improving disease risk stratification in individuals with alpha-1 antitrypsin deficiency, including genetic carriers.

Publications

  • Published 3/4/2025

    Zhang J, Hobbs BD, Silverman EK, Sparrow D, Ortega VE, Xu H, Zhang C, Dupuis J, Walkey AJ, O'Connor GT, Cho MH, Moll M. Polygenic Risk Score Added to Conventional Case Finding to Identify Undiagnosed Chronic Obstructive Pulmonary Disease. JAMA. 2025 Mar 04; 333(9):784-792. PMID: 39841442.

    Read at: PubMed

  • Published 11/6/2024

    Moll M, Hecker J, Platig J, Zhang J, Ghosh AJ, Pratte KA, Wang RS, Hill D, Konigsberg IR, Chiles JW, Hersh CP, Castaldi PJ, Glass K, Dy JG, Sin DD, Tal-Singer R, Mouded M, Rennard SI, Anderson GP, Kinney GL, Bowler RP, Curtis JL, McDonald ML, Silverman EK, Hobbs BD, Cho MH. Polygenic and transcriptional risk scores identify chronic obstructive pulmonary disease subtypes in the COPDGene and ECLIPSE cohort studies. EBioMedicine. 2024 Dec; 110:105429. PMID: 39509750.

    Read at: PubMed

  • Published 10/1/2024

    Zhang J, Moll M, Hobbs BD, Bakke P, Regan EA, Xu H, Dupuis J, Chiles JW, McDonald MN, Divo MJ, Silverman EK, Celli BR, O'Connor GT, Cho MH. Genetically Predicted Body Mass Index and Mortality in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2024 Oct 01; 210(7):890-899. PMID: 38471013.

    Read at: PubMed

  • Published 6/22/2024

    Shen BH, Dobie AC, Shusterman SL, Duzgol M, Homer-Bouthiette C, Kearney LE, Newman J, Pang B, Shankar DA, Zhang J, Gillmeyer KR, Bosch NA, Law AC. Variation in Triage to Pediatric vs Adult ICUs Among Adolescents and Young Adults With Asthma Exacerbations. CHEST Crit Care. 2024 Sep; 2(3). PMID: 39364391.

    Read at: PubMed

  • Published 1/1/2023

    Pang B, Kearney L, Maccarone J, Zhang J, Kearney C, Sangani R, Shankar DA, Gillmeyer KR, Law AC, Bosch NA. Association between Early Venous Thromboembolism Prophylaxis, Bleeding Risk, and Venous Thromboembolism among Critically Ill Patients with Thrombocytopenia. Ann Am Thorac Soc. 2023; 20(6):917-920.

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