Jimmy Walter Crott
Associate Professor, Pathology & Laboratory Medicine
Biography
Jimmy Crott, PhD, Pathology & Laboratory Medicine, studies the interaction between diet, gut microbiome, colon tumorigenesis and aging. His ongoing projects involve identifying the active component of a chemoprotective bacterium, understanding the role of gut barrier integrity and tight junction proteins in aging and understanding the role of the gut microbiome in colon cancer prevention by a Mediterranean diet. He came to BU/BMC in February 2022 from Tufts University, where he served in a variety of roles over 20 years, most recently as the leader of the Microbiome and Aging Program at the Jean Mayer USDA Human Nutrition Research Center on Aging and strategic initiative advisor in the Office of the Vice Provost of Research.
Education
- University of Adelaide, PhD
- University of Adelaide, BSc
- University of Adelaide, BSc
Publications
- Published on 6/21/2023
Shaikh SR, Crott JW, Comstock SS, Yeruva L, Davis TA. Nutritional Immunology Across the Lifespan: A Call for Papers. J Nutr. 2023 Aug; 153(8):2135-2136. PMID: 37349203.
Read at: PubMed - Published on 12/17/2021
Simas AM, Crott JW, Sedore C, Rohrbach A, Monaco AP, Gabriel SB, Lennon N, Blumenstiel B, Genco CA. Pooling for SARS-CoV2 Surveillance: Validation and Strategy for Implementation in K-12 Schools. Front Public Health. 2021; 9:789402. PMID: 34976934.
Read at: PubMed - Published on 12/3/2021
Wu X, Ueland PM, Roper J, Koh GY, Liang X, Crott JW, Yilmaz ÖH, Bronson RT, Mason JB. Combined Supplementation with Vitamin B-6 and Curcumin is Superior to Either Agent Alone in Suppressing Obesity-Promoted Colorectal Tumorigenesis in Mice. J Nutr. 2021 12 03; 151(12):3678-3688. PMID: 34590119.
Read at: PubMed - Published on 7/14/2020
Koh GY, Kane AV, Wu X, Crott JW. Parabacteroides distasonis attenuates tumorigenesis, modulates inflammatory markers and promotes intestinal barrier integrity in azoxymethane-treated A/J mice. Carcinogenesis. 2020 07 14; 41(7):909-917. PMID: 32115637.
Read at: PubMed - Published on 2/4/2019
Wu X, Koh GY, Huang Y, Crott JW, Bronson RT, Mason JB. The Combination of Curcumin and Salsalate is Superior to Either Agent Alone in Suppressing Pro-Cancerous Molecular Pathways and Colorectal Tumorigenesis in Obese Mice. Mol Nutr Food Res. 2019 04; 63(8):e1801097. PMID: 30680927.
Read at: PubMed - Published on 10/5/2018
Pfalzer AC, Leung K, Crott JW, Kim SJ, Tai AK, Parnell LD, Kamanu FK, Liu Z, Rogers G, Shea MK, Garcia PE, Mason JB. Incremental Elevations in TNFa and IL6 in the Human Colon and Procancerous Changes in the Mucosal Transcriptome Accompany Adiposity. Cancer Epidemiol Biomarkers Prev. 2018 12; 27(12):1416-1423. PMID: 30291114.
Read at: PubMed - Published on 10/1/2018
Koh GY, Kane A, Lee K, Xu Q, Wu X, Roper J, Mason JB, Crott JW. Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice. Int J Cancer. 2018 10 01; 143(7):1797-1805. PMID: 29696632.
Read at: PubMed - Published on 10/1/2018
Pfalzer AC, Crott JW, Koh GY, Smith DE, Garcia PE, Mason JB. Interleukin-1 Signaling Mediates Obesity-Promoted Elevations in Inflammatory Cytokines, Wnt Activation, and Epithelial Proliferation in the Mouse Colon. J Interferon Cytokine Res. 2018 10; 38(10):445-451. PMID: 30328795.
Read at: PubMed - Published on 8/11/2017
Wu X, Pfalzer AC, Koh GY, Tang S, Crott JW, Thomas MJ, Meydani M, Mason JB. Curcumin and Salsalate Suppresses Colonic Inflammation and Procarcinogenic Signaling in High-Fat-Fed, Azoxymethane-Treated Mice. J Agric Food Chem. 2017 Aug 23; 65(33):7200-7209. PMID: 28745498.
Read at: PubMed - Published on 11/16/2016
Crott JW. Effects of altered parental folate and one-carbon nutrient status on offspring growth and metabolism. Mol Aspects Med. 2017 02; 53:28-35. PMID: 27865887.
Read at: PubMed
View 43 more publications: View full profile at BUMC