Jie Yang, PhD

Research Assistant Professor, Pediatrics

Jie Yang
617.358.1124
jieyang5@bu.edu
650 Albany St
View full profile at BUMC

Biography

Dr. Yang works on the study of protein folding, misfolding and assembly using single molecule fluorescence and force spectroscopy techniques.

Websites

Education

  • Chinese Academy of Sciences, PhD
  • Shandong University, BS

Publications

  • Published on 3/26/2024

    Meijer M, Öttl M, Yang J, Subkhangulova A, Kumar A, Feng Z, van Voorst TW, Groffen AJ, van Weering JRT, Zhang Y, Verhage M. Tomosyns attenuate SNARE assembly and synaptic depression by binding to VAMP2-containing template complexes. Nat Commun. 2024 Mar 26; 15(1):2652. PMID: 38531902.

    Read at: PubMed
  • Published on 10/13/2023

    Ren Y, Yang J, Fujita B, Jin H, Zhang Y, Berro J. Force redistribution in clathrin-mediated endocytosis revealed by coiled-coil force sensors. Sci Adv. 2023 Oct 13; 9(41):eadi1535. PMID: 37831774.

    Read at: PubMed
  • Published on 12/1/2022

    Yang J, Jin H, Liu Y, Guo Y, Zhang Y. A dynamic template complex mediates Munc18-chaperoned SNARE assembly. Proc Natl Acad Sci U S A. 2022 Dec 06; 119(49):e2215124119. PMID: 36454760.

    Read at: PubMed
  • Published on 1/1/2022

    Jin H, Ge J, Yang J, Zhang Y. Single-Molecule Manipulation Study of Chaperoned SNARE Folding and Assembly with Optical Tweezers. Methods Mol Biol. 2022; 2478:461-481. PMID: 36063331.

    Read at: PubMed
  • Published on 12/16/2021

    Ge J, Bian X, Ma L, Cai Y, Li Y, Yang J, Karatekin E, De Camilli P, Zhang Y. Stepwise membrane binding of extended synaptotagmins revealed by optical tweezers. Nat Chem Biol. 2022 Mar; 18(3):313-320. PMID: 34916620.

    Read at: PubMed
  • Published on 2/11/2021

    Yang J, Perrett S, Wu S. Single Molecule Characterization of Amyloid Oligomers. Molecules. 2021 Feb 11; 26(4). PMID: 33670093.

    Read at: PubMed
  • Published on 12/5/2020

    Kalyana Sundaram RV, Jin H, Li F, Shu T, Coleman J, Yang J, Pincet F, Zhang Y, Rothman JE, Krishnakumar SS. Munc13 binds and recruits SNAP25 to chaperone SNARE complex assembly. FEBS Lett. 2021 Feb; 595(3):297-309. PMID: 33222163.

    Read at: PubMed
  • Published on 8/14/2020

    Yang J, Dear AJ, Yao QQ, Liu Z, Dobson CM, Knowles TPJ, Wu S, Perrett S. Amelioration of aggregate cytotoxicity by catalytic conversion of protein oligomers into amyloid fibrils. Nanoscale. 2020 Sep 28; 12(36):18663-18672. PMID: 32794533.

    Read at: PubMed
  • Published on 3/20/2020

    Wu S, Hong L, Wang Y, Yu J, Yang J, Yang J, Zhang H, Perrett S. Kinetics of the conformational cycle of Hsp70 reveals the importance of the dynamic and heterogeneous nature of Hsp70 for its function. Proc Natl Acad Sci U S A. 2020 Apr 07; 117(14):7814-7823. PMID: 32198203.

    Read at: PubMed
  • Published on 2/7/2018

    Yang J, Dear AJ, Michaels TCT, Dobson CM, Knowles TPJ, Wu S, Perrett S. Direct Observation of Oligomerization by Single Molecule Fluorescence Reveals a Multistep Aggregation Mechanism for the Yeast Prion Protein Ure2. J Am Chem Soc. 2018 Feb 21; 140(7):2493-2503. PMID: 29357227.

    Read at: PubMed

View 1 more publications: View full profile at BUMC

View all profiles