Jan K. Blusztajn, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Jan K. Blusztajn, PhD is a Professor of Pathology in the Department of Pathology & Laboratory Medicine at the Chobanian and Avedisian School of Medicine. Dr. Blusztajn received his PhD in Neural and Endocrine Regulation from the Massachusetts Institute of Technology. Dr. Blusztajn's research is in prenatal programming of brain development and aging by essential nutrient availability during gestation.

Publications

  • Published 10/13/2025

    Bellio TA, Krunic A, Campion MS, Dupaguntla R, Labadorf A, Stein TD, Lin H, Mellott TJ, Blusztajn JK. Perinatal Choline Supplementation Promotes Resilience Against Progression of Alzheimer's Disease-Like Brain Transcriptomic Signatures in AppNL-G-F Mice. Aging Cell. 2025 Oct 13; e70148. PMID: 41081549.

    Read at: PubMed

  • Published 10/13/2025

    Krunic A, Bellio TA, Cohen BZ, Labadorf A, Stein TD, Lin H, Mellott TJ, Blusztajn JK. Brain DNA Methylation Atlas of AppNL-G-F Alzheimer's Disease Model Mice Across Age and Region Reveals Choline-Induced Resilience. Aging Cell. 2025 Oct 13; e70241. PMID: 41081550.

    Read at: PubMed

  • Published 9/18/2024

    Liu S, Park T, Krüger DM, Pena-Centeno T, Burkhardt S, Schutz AL, Huang YN, Rosewood T, Chaudhuri S, Cho M, Risacher SL, Wan Y, Shaw LM, Sananbenesi F, Brodsky AS, Lin H, Krunic A, Blusztajn JK, Saykin AJ, Delalle I, Fischer A, Nho K. Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers. Alzheimers Dement. 2024 Nov; 20(11):7698-7714. PMID: 39291737.

    Read at: PubMed

  • Published 9/18/2024

    Krüger DM, Pena-Centeno T, Liu S, Park T, Kaurani L, Pradhan R, Huang YN, Risacher SL, Burkhardt S, Schütz AL, Wan Y, Shaw LM, Brodsky AS, DeStefano AL, Lin H, Schroeder R, Krunic A, Hempel N, Sananbenesi F, Blusztajn JK, Saykin AJ, Delalle I, Nho K, Fischer A. The plasma miRNAome in ADNI: Signatures to aid the detection of at-risk individuals. Alzheimers Dement. 2024 Nov; 20(11):7479-7494. PMID: 39291752.

    Read at: PubMed

  • Published 2/5/2024

    Bellio TA, Laguna-Torres JY, Campion MS, Chou J, Yee S, Blusztajn JK, Mellott TJ. Perinatal choline supplementation prevents learning and memory deficits and reduces brain amyloid Aß42 deposition in AppNL-G-F Alzheimer's disease model mice. PLoS One. 2024; 19(2):e0297289. PMID: 38315685.

    Read at: PubMed

Other Positions

  • Research Professor, Psychiatry
    Boston University Chobanian & Avedisian School of Medicine
  • Member, BU-BMC Cancer Center
    Boston University
  • Investigator
    Framingham Heart Study
  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University
  • Member, Genome Science Institute
    Boston University
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Education

  • Massachusetts Institute of Technology, PhD
  • University of Warsaw, MS