Hugo Javier Aparicio, MD, MPH

Associate Professor, Neurology

Hugo Aparicio
617.358.9781
72 E. Concord St Robinson (B)

Biography

Dr. Aparicio’s research interests include the identification of lifestyle risk factors, biomarkers, neuroimaging markers and genetic influences associated with cerebrovascular diseases. He is particularly interested in the contributions of vascular risk factors to stroke, brain injury and aging, cognitive dysfunction and the development of Alzheimer’s disease and the influence of racial and ethnic disparities on these outcomes.

Other Positions

  • Investigator, Framingham Heart Study

Education

  • University of Pennsylvania School of Medicine, MD
  • Harvard School of Public Health, MPH
  • Emory University, BA

Publications

  • Published on 5/1/2024

    DeCarli C, Maillard P, Pase MP, Beiser AS, Kojis D, Satizabal CL, Himali JJ, Aparicio HJ, Fletcher E, Seshadri S. Trends in Intracranial and Cerebral Volumes of Framingham Heart Study Participants Born 1930 to 1970. JAMA Neurol. 2024 May 01; 81(5):471-480. PMID: 38526486.

    Read at: PubMed
  • Published on 4/2/2024

    Kelly DM, Pinheiro AA, Koini M, Anderson CD, Aparicio H, Hofer E, Kern D, Blacker D, DeCarli C, Hwang SJ, Viswanathan A, Gonzales MM, Beiser AS, Seshadri S, Schmidt R, Demissie S, Romero JR. Impaired Kidney Function, Cerebral Small Vessel Disease and Cognitive Disorders: The Framingham Heart Study. Nephrol Dial Transplant. 2024 Apr 02. PMID: 38565317.

    Read at: PubMed
  • Published on 2/1/2024

    Elmore A, Adhikari N, Hartley AE, Javier Aparicio H, Posner DC, Hemani G, Tilling K, Gaunt TR, Wilson P, Casas JP, Michael Gaziano J, Smith GD, Paternoster L, Cho K, Peloso GM. Protein identification for stroke progression via Mendelian Randomization in Million Veteran Program and UK Biobank. medRxiv. 2024 Feb 01. PMID: 38352469.

    Read at: PubMed
  • Published on 1/30/2024

    Pase MP, Himali JJ, Puerta R, Beiser AS, Gonzales MM, Satizabal CL, Yang Q, Aparicio HJ, Kojis DJ, Decarli CS, Lopez OL, Longstreth W, Gudnason V, Mosley TH, Bis JC, Fohner A, Psaty BM, Boada M, García-González P, Valero S, Marquié M, Tracy R, Launer LJ, Ruiz A, Fornage M, Seshadri S. Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia. Neurology. 2024 Feb 27; 102(4):e208075. PMID: 38290090.

    Read at: PubMed
  • Published on 12/30/2023

    Montoliu-Gaya L, Alosco ML, Yhang E, Tripodis Y, Sconzo D, Ally M, Grötschel L, Ashton NJ, Lantero-Rodriguez J, Sauer M, Gomes B, Nilsson J, Brinkmalm G, Sugarman MA, Aparicio HJ, Martin B, Palmisano JN, Steinberg EG, Simkin I, Turk KW, Budson AE, Au R, Farrer L, Jun GR, Kowall NW, Stern RA, Goldstein LE, Qiu WQ, Mez J, Huber BR, Alvarez VE, McKee AC, Zetterberg H, Gobom J, Stein TD, Blennow K. Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study. Acta Neuropathol. 2023 Dec 30; 147(1):5. PMID: 38159140.

    Read at: PubMed
  • Published on 12/12/2023

    Song RJ, Larson MG, Aparicio HJ, Gaziano JM, Wilson P, Cho K, Vasan RS, Fox MP, Djoussé L. Moderate alcohol consumption on the risk of stroke in the Million Veteran Program. BMC Public Health. 2023 Dec 12; 23(1):2485. PMID: 38087273.

    Read at: PubMed
  • Published on 11/1/2023

    Sheehy S, Aparicio HJ, Palmer JR, Cozier Y, Lioutas VA, Shulman JG, Rosenberg L. Perceived Interpersonal Racism and Incident Stroke Among US Black Women. JAMA Netw Open. 2023 Nov 01; 6(11):e2343203. PMID: 37948073.

    Read at: PubMed
  • Published on 10/25/2023

    Ally M, Sugarman MA, Zetterberg H, Blennow K, Ashton NJ, Karikari TK, Aparicio HJ, Frank B, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Simkin I, Farrer LA, Jun GR, Turk KW, Budson AE, O'Connor MK, Au R, Goldstein LE, Kowall NW, Killiany R, Stern RA, Stein TD, McKee AC, Qiu WQ, Mez J, Alosco ML. Cross-sectional and longitudinal evaluation of plasma glial fibrillary acidic protein to detect and predict clinical syndromes of Alzheimer's disease. Alzheimers Dement (Amst). 2023; 15(4):e12492. PMID: 37885919.

    Read at: PubMed
  • Published on 10/19/2023

    Petrea RE, Pinheiro A, Demissie S, Ekenze O, Aparicio HJ, Satizabal CL, Maillard P, DeCarli C, Beiser AS, Seshadri S, Lioutas VA, Rafael Romero J. Hypertension Trends and White Matter Brain Injury in the Offspring Framingham Heart Study Cohort. Hypertension. 2024 Jan; 81(1):87-95. PMID: 37855140.

    Read at: PubMed
  • Published on 9/12/2023

    Vered S, Beiser AS, Sulimani L, Sznitman S, Gonzales MM, Aparicio HJ, DeCarli C, Scott MR, Ghosh S, Lewitus GM, Meiri D, Seshadri S, Weinstein G. The association of circulating endocannabinoids with neuroimaging and blood biomarkers of neuro-injury. Alzheimers Res Ther. 2023 Sep 12; 15(1):154. PMID: 37700370.

    Read at: PubMed

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