Hugo Javier Aparicio, MD, MPH

Associate Professor, Neurology

Hugo Aparicio
72 E. Concord St Robinson (B)


Dr. Aparicio’s research interests include the identification of lifestyle risk factors, biomarkers, neuroimaging markers and genetic influences associated with cerebrovascular diseases. He is particularly interested in the contributions of vascular risk factors to stroke, brain injury and aging, cognitive dysfunction and the development of Alzheimer’s disease and the influence of racial and ethnic disparities on these outcomes.

Other Positions

  • Investigator, Framingham Heart Study


  • University of Pennsylvania School of Medicine, MD
  • Harvard School of Public Health, MPH
  • Emory University, BA


  • Published on 9/22/2023

    Pase MP, Pinheiro A, Rowsthorn E, Demissie S, Hurmez S, Aparicio H, Rodriguez-Lara F, Gonzales MM, Beiser A, DeCarli C, Seshadri S, Romero JR. MRI Visible Perivascular Spaces and the Risk of Incident Mild Cognitive Impairment in a Community Sample. J Alzheimers Dis. 2023 Sep 22. PMID: 37742645.

    Read at: PubMed
  • Published on 9/12/2023

    Vered S, Beiser AS, Sulimani L, Sznitman S, Gonzales MM, Aparicio HJ, DeCarli C, Scott MR, Ghosh S, Lewitus GM, Meiri D, Seshadri S, Weinstein G. The association of circulating endocannabinoids with neuroimaging and blood biomarkers of neuro-injury. Alzheimers Res Ther. 2023 Sep 12; 15(1):154. PMID: 37700370.

    Read at: PubMed
  • Published on 8/23/2023

    Aparicio HJ. Healthy Lifestyle for Healthier Arteries in People With Type 2 Diabetes. J Am Heart Assoc. 2023 Sep 05; 12(17):e030594. PMID: 37609983.

    Read at: PubMed
  • Published on 8/22/2023

    Melo van Lent D, Mesa HG, Short MI, Gonzales MM, Aparicio HJ, Salinas J, Yuan C, Jacques PF, Beiser A, Seshadri S, Jacob ME, Himali JJ. Association between dietary inflammatory index score and incident dementia: results from the Framingham heart Study offspring cohort. medRxiv. 2023 Aug 22. PMID: 37662354.

    Read at: PubMed
  • Published on 5/16/2023

    Bilski AE, Aparicio HJ, Gutierrez J, de Leeuw FE, Hilkens NA. Antiplatelet Therapy or Not for Asymptomatic/Incidental Lacunar Infarction. Stroke. 2023 Jul; 54(7):1954-1959. PMID: 37191009.

    Read at: PubMed
  • Published on 5/15/2023

    Hingorani KS, Barnes E, Carneiro T, Sader E, Anand P, Ong CJ, Chung D, Daneshmand A, Suchdev K, Takahashi C, Greer D, Shulman JG, Aparicio HJ, Nguyen TN, Romero JR, AbdalKader M, Feske SK, Kimmel SD, Weinstein ZM, Fagan M, Dobrilovic N, Awtry E, Cervantes-Arslanian AM. Strokes in Patients With Injection Drug Use and Tricuspid Valve Endocarditis - A Case Series. Neurohospitalist. 2023 Jul; 13(3):272-277. PMID: 37441214.

    Read at: PubMed
  • Published on 5/1/2023

    Levine DA, Chen B, Galecki AT, Gross AL, Briceño EM, Whitney RT, Ploutz-Snyder RJ, Giordani BJ, Sussman JB, Burke JF, Lazar RM, Howard VJ, Aparicio HJ, Beiser AS, Elkind MSV, Gottesman RF, Koton S, Pendlebury ST, Sharma A, Springer MV, Seshadri S, Romero JR, Hayward RA. Associations Between Vascular Risk Factor Levels and Cognitive Decline Among Stroke Survivors. JAMA Netw Open. 2023 May 01; 6(5):e2313879. PMID: 37195662.

    Read at: PubMed
  • Published on 5/1/2023

    Scollard P, Choi SE, Lee ML, Mukherjee S, Trittschuh EH, Sanders RE, Gibbons LE, Joshi P, Devine S, Au R, Dams-O'Connor K, Saykin AJ, Seshadri S, Beiser A, Aparicio HJ, Salinas J, Gonzales MM, Pase MP, Ghosh S, Finney R, Mez J, Crane PK. Ceiling effects and differential measurement precision across calibrated cognitive scores in the Framingham Study. Neuropsychology. 2023 May; 37(4):383-397. PMID: 37276135.

    Read at: PubMed
  • Published on 5/1/2023

    El Husseini N, Katzan IL, Rost NS, Blake ML, Byun E, Pendlebury ST, Aparicio HJ, Marquine MJ, Gottesman RF, Smith EE. Cognitive Impairment After Ischemic and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association/American Stroke Association. Stroke. 2023 Jun; 54(6):e272-e291. PMID: 37125534.

    Read at: PubMed
  • Published on 1/30/2023

    DeCarli C, Pase M, Beiser A, Kojis D, Satizabal C, Himali J, Aparicio H, Flether E, Maillard P, Seshadri S. Secular Trends in Head Size and Cerebral Volumes In the Framingham Heart Study for Birth Years 1902-1985. Res Sq. 2023 Jan 30. PMID: 36778357.

    Read at: PubMed

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