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Published 9/8/2025
Jalloh S, Hughes IK, Akiyama H, Gojanovich AD, Quiñones-Molina AA, Yang M, Henderson AJ, Mostoslavsky G, Gummuluru S. Expression of intron-containing HIV-1 RNA induces NLRP1 inflammasome activation in myeloid cells. PLoS Biol. 2025 Sep; 23(9):e3003320. PMID: 40920844.
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Published 8/25/2025
Hughes IK, Kharytonchyk S, Ramaswamy S, Jalloh S, Hood JB, He X, Henderson AJ, Akiyama H, Telesnitsky A, Gummuluru S. 5' cap sequestration is required for sensing of unspliced HIV-1 RNA by MDA5. bioRxiv. 2025 Aug 25. PMID: 40909469.
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Published 6/10/2025
Ramaswamy S, Akiyama H, Berrigan J, Quiñones-Molina AA, Olson AJ, Chen Y, Liang Y, Henderson AJ, Asundi A, Sagar M, Gummuluru S. The macrophage-intrinsic MDA5/IRF5 axis drives HIV-1 intron-containing RNA-induced inflammatory responses. J Clin Invest. 2025 Aug 15; 135(16). PMID: 40493408.
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Published 5/19/2025
Hughes IK, Hood JB, Quiñones-Molina AA, Akiyama H, Gummuluru S. Evasion of CARD8 Activation During HIV-1 Assembly. bioRxiv. 2025 May 19. PMID: 40475532.
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Published 11/1/2023
Komori M, Morey AL, Quiñones-Molina AA, Fofana J, Romero L, Peters E, Matsuda K, Gummuluru S, Smith JF, Akahata W, Akiyama H. Incorporation of 5 methylcytidine alleviates innate immune response to self-amplifying RNA vaccine. bioRxiv. 2023 Nov 01. PMID: 37961509.