Hiroshi Mashimo, MD, PhD

Adjunct Assistant Professor, Medicine

Hiroshi Mashimo
72 E. Concord St Building A


Hiroshi Mashimo is currently Chief of Gastroenterology at the VA Boston Healthcare System, Assistant Professor of Medicine at Harvard Medical School and Adjunct Assistant Professor Of Medicine at Chobanian and Avedisian School of Medicine. He obtained his A.B. at Harvard College and his M.S., M.D. and Ph.D. degrees at Albert Einstein College of Medicine. He completed his medical internship, residency, and gastroenterology fellowship at Massachusetts General Hospital. His interest in molecular physiology led to advanced research and clinical training at Harvard Medical School, with Dr Daniel K. Podolsky and Dr Mark C. Fishman at Massachusetts General Hospital, and with Dr Raj K. Goyal at Beth Israel Hospital. His pioneering work using genetically altered mice models to understand basic gastrointestinal physiology has led to important understandings of the distinct roles of various mediators such as nitric oxide synthases and vasoactive intestinal peptides in the field of gastrointestinal motility. He has continued his interest in clinical gastrointestinal motility as Director of the Swallowing and Motility Disorders services at the VA Boston Healthcare, and is involved with training and teaching of students, residents and fellows at Brigham and Women’s Hospital, the VA Boston Healthcare, and Harvard Medical School. He has published numerous original and review articles in various medical and scientific journals.

Other Positions

  • VA Boston Healthcare System



  • Albert Einstein College of Medicine, MD
  • Albert Einstein College of Medicine, PhD
  • Yeshiva University, MS
  • Harvard College, AB


  • Published on 7/20/2023

    Triadafilopoulos G, Mashimo H, Tatum R, O'Clarke J, Hawn M. Mixed Esophageal Disease (MED): A New Concept. Dig Dis Sci. 2023 Sep; 68(9):3542-3554. PMID: 37470896.

    Read at: PubMed
  • Published on 5/12/2023

    Kumar S, Zhao J, Talluri S, Buon L, Mu S, Potluri LB, Liao C, Shi J, Chakraborty C, Gonzalez GB, Tai YT, Patel J, Pal J, Mashimo H, Samur MK, Munshi NC, Shammas MA. Elevated APE1 Dysregulates Homologous Recombination and Cell Cycle Driving Genomic Evolution, Tumorigenesis, and Chemoresistance in Esophageal Adenocarcinoma. Gastroenterology. 2023 Aug; 165(2):357-373. PMID: 37178737.

    Read at: PubMed
  • Published on 11/15/2022

    Guadagnoli L, Mashimo H, Lo WK. Assessment of Post-traumatic Stress Disorder Among Objective Esophageal Motility and Reflux Phenotypes in Symptomatic Veterans. J Clin Psychol Med Settings. 2023 Sep; 30(3):606-617. PMID: 36378471.

    Read at: PubMed
  • Published on 3/26/2021

    Zhang J, Nguyen T, Potsaid B, Jayaraman V, Burgner C, Chen S, Li J, Liang K, Cable A, Traverso G, Mashimo H, Fujimoto JG. Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural and angiographic imaging with miniaturized brushless motor probes. Biomed Opt Express. 2021 Apr 01; 12(4):2384-2403. PMID: 33996236.

    Read at: PubMed
  • Published on 1/30/2021

    Fass OZ, Mashimo H. The Effect of Bariatric Surgery and Endoscopic Procedures on Gastroesophageal Reflux Disease. J Neurogastroenterol Motil. 2021 Jan 30; 27(1):35-45. PMID: 33380553.

    Read at: PubMed
  • Published on 12/9/2020

    Nguyen TH, Ahsen OO, Liang K, Zhang J, Mashimo H, Fujimoto JG. Correction of circumferential and longitudinal motion distortion in high-speed catheter/endoscope-based optical coherence tomography. Biomed Opt Express. 2021 Jan 01; 12(1):226-246. PMID: 33520383.

    Read at: PubMed
  • Published on 11/12/2020

    Mashimo H, Gordon SR, Singh SK. Advanced endoscopic imaging for detecting and guiding therapy of early neoplasias of the esophagus. Ann N Y Acad Sci. 2020 12; 1482(1):61-76. PMID: 33184872.

    Read at: PubMed
  • Published on 9/16/2020

    Rodriguez-Diaz E, Baffy G, Lo WK, Mashimo H, Vidyarthi G, Mohapatra SS, Singh SK. Real-time artificial intelligence-based histologic classification of colorectal polyps with augmented visualization. Gastrointest Endosc. 2021 03; 93(3):662-670. PMID: 32949567.

    Read at: PubMed
  • Published on 9/1/2020

    Liang K, Ahsen OO, Murphy A, Zhang J, Nguyen TH, Potsaid B, Figueiredo M, Huang Q, Mashimo H, Fujimoto JG. Tethered capsule en face optical coherence tomography for imaging Barrett's oesophagus in unsedated patients. BMJ Open Gastroenterol. 2020 09; 7(1). PMID: 32883714.

    Read at: PubMed
  • Published on 9/1/2020

    Banting SP, Badgery HE, Read M, Mashimo H. Rethinking gastroesophageal reflux disorder. Ann N Y Acad Sci. 2020 12; 1482(1):177-192. PMID: 32875572.

    Read at: PubMed

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