Hengye Man, MD, PhD

Professor, Biology

5 Cummington St

Other Positions

  • Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
  • Professor, Neuroscience, Boston University College of Arts and Sciences
  • Associate Professor, Pharmacology, Physiology & Biophysics, Boston University Chobanian & Avedisian School of Medicine


  • Taishan Medical University, MD
  • University of Toronto, PhD
  • University of Toronto, PhD
  • Shandong Medical University, MSc


  • Published on 3/18/2024

    Gardner Z, Holbrook O, Tian Y, Odamah K, Man HY. The role of glia in the dysregulation of neuronal spinogenesis in Ube3a-dependent ASD. Exp Neurol. 2024 Jun; 376:114756. PMID: 38508482.

    Read at: PubMed
  • Published on 2/5/2024

    Tian Y, Yu F, Yun E, Lin JW, Man HY. mRNA nuclear retention reduces AMPAR expression and promotes autistic behavior in UBE3A-overexpressing mice. EMBO Rep. 2024 Mar; 25(3):1282-1309. PMID: 38316900.

    Read at: PubMed
  • Published on 1/24/2024

    O'Connor M, Qiao H, Odamah K, Cerdeira PC, Man HY. Heterozygous Nexmif female mice demonstrate mosaic NEXMIF expression, autism-like behaviors, and abnormalities in dendritic arborization and synaptogenesis. Heliyon. 2024 Feb 15; 10(3):e24703. PMID: 38322873.

    Read at: PubMed
  • Published on 6/14/2022

    Qiao H, Tian Y, Huo Y, Man HY. Role of the DUB enzyme USP7 in dendritic arborization, neuronal migration, and autistic-like behaviors in mice. iScience. 2022 Jul 15; 25(7):104595. PMID: 35800757.

    Read at: PubMed
  • Published on 6/10/2022

    Huo Y, Lu W, Tian Y, Hou Q, Man HY. Prkn knockout mice show autistic-like behaviors and aberrant synapse formation. iScience. 2022 Jul 15; 25(7):104573. PMID: 35789851.

    Read at: PubMed
  • Published on 10/12/2021

    Xiao S, Lowet E, Gritton HJ, Fabris P, Wang Y, Sherman J, Mount RA, Tseng HA, Man HY, Straub C, Piatkevich KD, Boyden ES, Mertz J, Han X. Large-scale voltage imaging in behaving mice using targeted illumination. iScience. 2021 Nov 19; 24(11):103263. PMID: 34761183.

    Read at: PubMed
  • Published on 7/14/2021

    Shi L, Jiang Y, Fernandez FR, Chen G, Lan L, Man HY, White JA, Cheng JX, Yang C. Non-genetic photoacoustic stimulation of single neurons by a tapered fiber optoacoustic emitter. Light Sci Appl. 2021 Jul 14; 10(1):143. PMID: 34257273.

    Read at: PubMed
  • Published on 8/15/2020

    O'Connor M, Shentu YP, Wang G, Hu WT, Xu ZD, Wang XC, Liu R, Man HY. Acetylation of AMPA Receptors Regulates Receptor Trafficking and Rescues Memory Deficits in Alzheimer's Disease. iScience. 2020 Sep 25; 23(9):101465. PMID: 32861999.

    Read at: PubMed
  • Published on 6/30/2020

    Bensussen S, Shankar S, Ching KH, Zemel D, Ta TL, Mount RA, Shroff SN, Gritton HJ, Fabris P, Vanbenschoten H, Beck C, Man HY, Han X. A Viral Toolbox of Genetically Encoded Fluorescent Synaptic Tags. iScience. 2020 Jul 24; 23(7):101330. PMID: 32674057.

    Read at: PubMed
  • Published on 3/16/2020

    Hastings MH, Gauthier JM, Mabry K, Tran A, Man HY, Kantak KM. Facilitative effects of environmental enrichment for cocaine relapse prevention are dependent on extinction training context and involve increased TrkB signaling in dorsal hippocampus and ventromedial prefrontal cortex. Behav Brain Res. 2020 05 27; 386:112596. PMID: 32194188.

    Read at: PubMed

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