Gary B. Kaplan, MD

Emeritus Professor, Psychiatry

Gary Kaplan
150 S Huntington Ave


Dr. Kaplan serves as the Director of the Mental Health Service and Chief of Psychiatry at VA Boston Healthcare System. His clinical and pre-clinical and research focus is within the neurobiology and neuropharmacology of addiction, schizophrenia, and conditioned fear. His research specifically examines conditioned drug reward and its extinction and is published in journals of neuroscience and pharmacology.

Dr. Kaplan currently serves on the editorial board the Journal of Clinical Pharmacology. His national role in psychiatry has been recognized by the American Psychiatric Association where he was conferred as a Distinguished Fellow. He is the lead author of a text for the American Psychiatric Press Inc. for psychiatric clinicians and residents entitled Brain Circuitry and Signaling in Psychiatry which examines the functional circuitry and neurochemical pathways in psychiatric illnesses.

Dr. Kaplan is a graduate of University of Pennsylvania and Drexel University College of Medicine (Hahnemann). His residency training in Psychiatry and post-doctoral research training in Pharmacology were at Tufts University School of Medicine.

Other Positions

  • Professor, Pharmacology, Physiology & Biophysics, Boston University Chobanian & Avedisian School of Medicine
  • VA Boston Healthcare System
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences


  • Hahnemann University, MD
  • University of Pennsylvania, BA


  • Published on 11/16/2023

    Kaplan GB, Thompson BL. Neuroplasticity of the extended amygdala in opioid withdrawal and prolonged opioid abstinence. Front Pharmacol. 2023; 14:1253736. PMID: 38044942.

    Read at: PubMed
  • Published on 8/25/2023

    Babb JA, Constantino NJ, Kaplan GB, Chartoff EH. Estrous cycle dependent expression of oxycodone conditioned reward in rats. Sci Rep. 2023 Aug 25; 13(1):13946. PMID: 37626154.

    Read at: PubMed
  • Published on 4/7/2023

    Babb JA, Zuberer A, Heinrichs S, Rumbika KK, Alfiler L, Lakis GA, Leite-Morris KA, Kaplan GB. Disturbances in fear extinction learning after mild traumatic brain injury in mice are accompanied by alterations in dendritic plasticity in the medial prefrontal cortex and basolateral nucleus of the amygdala. Brain Res Bull. 2023 Jun 15; 198:15-26. PMID: 37031792.

    Read at: PubMed
  • Published on 2/15/2023

    Kaplan GB, Dadhi NA, Whitaker CS. Mitochondrial dysfunction in animal models of PTSD: Relationships between behavioral models, neural regions, and cellular maladaptation. Front Physiol. 2023; 14:1105839. PMID: 36923289.

    Read at: PubMed
  • Published on 7/30/2022

    Brown RE, Kaplan GB. Introduction to special issue: Sleep and arousal in health and disease. Brain Res Bull. 2022 Oct 01; 188:131-132. PMID: 35918033.

    Read at: PubMed
  • Published on 5/23/2022

    Kaplan GB, Lakis GA, Zhoba H. Sleep-wake and arousal dysfunctions in post-traumatic stress disorder: Role of orexin systems. Brain Res Bull. 2022 Aug; 186:106-122. PMID: 35618150.

    Read at: PubMed
  • Published on 5/10/2022

    Brown RE, Spratt TJ, Kaplan GB. Translational approaches to influence sleep and arousal. Brain Res Bull. 2022 Jul; 185:140-161. PMID: 35550156.

    Read at: PubMed
  • Published on 7/15/2021

    Liverant GI, Gallagher MW, Arditte Hall KA, Rosebrock LE, Black SK, Kind S, Fava M, Kaplan GB, Kamholz BW, Pineles SL, Sloan DM. Suppression and acceptance in unipolar depression: Short-term and long-term effects on emotional responding. Br J Clin Psychol. 2022 Mar; 61(1):1-17. PMID: 34268773.

    Read at: PubMed
  • Published on 11/2/2020

    Thompson BL, Oscar-Berman M, Kaplan GB. Opioid-induced structural and functional plasticity of medium-spiny neurons in the nucleus accumbens. Neurosci Biobehav Rev. 2021 01; 120:417-430. PMID: 33152423.

    Read at: PubMed
  • Published on 11/3/2017

    Kaplan GB, Leite-Morris KA, Wang L, Rumbika KK, Heinrichs SC, Zeng X, Wu L, Arena DT, Teng YD. Pathophysiological Bases of Comorbidity: Traumatic Brain Injury and Post-Traumatic Stress Disorder. J Neurotrauma. 2018 01 15; 35(2):210-225. PMID: 29017388.

    Read at: PubMed

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