David J. Waxman, PhD

Professor, Biology

David Waxman
5 Cummington St


David J. Waxman, PhD is a Biologist with extensive experience in the fields of biochemistry, molecular biology, and enzymology. Over the past 35 years, his lab has made seminal contributions to the research of cancer pharmacology and therapeutics, and steroid-metabolizing enzymes.
Dr. Waxman has spoken at over 130 conferences and has held appointments at a variety of universities including Harvard Medical School, MIT, and the Weizmann Institute.

Other Positions

  • Member, Genome Science Institute, Boston University
  • Professor, Gastroenterology, Medicine, Boston University Chobanian & Avedisian School of Medicine
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University


  • Harvard University, PhD
  • Harvard University, AM
  • Queens College, City University of New York, BA


  • Published on 8/22/2023

    Rampersaud A, Connerney J, Waxman DJ. Plasma Growth Hormone Pulsatility Directly Regulates Male-biased Chromatin Accessibility in Adult Mouse Liver. bioRxiv. 2023 Aug 22. PMID: 37662275.

    Read at: PubMed
  • Published on 5/13/2023

    Vázquez-Borrego MC, Del Río-Moreno M, Pyatkov M, Sarmento-Cabral A, Mahmood M, Pelke N, Wnek M, Cordoba-Chacon J, Waxman DJ, Puchowicz MA, McGuinness OP, Kineman RD. Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis. Metabolism. 2023 Jul; 144:155589. PMID: 37182789.

    Read at: PubMed
  • Published on 5/11/2023

    Karri K, Waxman DJ. TCDD dysregulation of lncRNA expression, liver zonation and intercellular communication across the liver lobule. Toxicol Appl Pharmacol. 2023 Jul 15; 471:116550. PMID: 37172768.

    Read at: PubMed
  • Published on 4/18/2023

    Everton E, Del Rio-Moreno M, Villacorta-Martin C, Singh Bawa P, Lindstrom-Vautrin J, Muramatsu H, Rizvi F, Smith AR, Tam Y, Pardi N, Kineman R, Waxman DJ, Gouon-Evans V. Growth Hormone Accelerates Recovery From Acetaminophen-Induced Murine Liver Injury. bioRxiv. 2023 Apr 18. PMID: 37131727.

    Read at: PubMed
  • Published on 4/4/2023

    Karri K, Waxman DJ. Dysregulation of murine long noncoding single-cell transcriptome in nonalcoholic steatohepatitis and liver fibrosis. RNA. 2023 Jul; 29(7):977-1006. PMID: 37015806.

    Read at: PubMed
  • Published on 1/8/2023

    Karri K, Waxman DJ. TCDD dysregulation of lncRNA expression, liver zonation and intercellular communication across the liver lobule. bioRxiv. 2023 Jan 08. PMID: 36711947.

    Read at: PubMed
  • Published on 10/20/2022

    Waxman DJ, Kineman RD. Sex matters in liver fat regulation. Science. 2022 Oct 21; 378(6617):252-253. PMID: 36264790.

    Read at: PubMed
  • Published on 7/30/2022

    Kim D, Kim B, Brocker CN, Karri K, Waxman DJ, Gonzalez FJ. Long non-coding RNA G23Rik attenuates fasting-induced lipid accumulation in mouse liver. Mol Cell Endocrinol. 2022 Nov 01; 557:111722. PMID: 35917881.

    Read at: PubMed
  • Published on 7/1/2022

    Goldfarb CN, Karri K, Pyatkov M, Waxman DJ. Interplay Between GH-regulated, Sex-biased Liver Transcriptome and Hepatic Zonation Revealed by Single-Nucleus RNA Sequencing. Endocrinology. 2022 Jul 01; 163(7). PMID: 35512247.

    Read at: PubMed
  • Published on 5/26/2022

    Shin A, Waxman DJ. Impact of Neonatal Activation of Nuclear Receptor CAR (Nr1i3) on Cyp2 Gene Expression in Adult Mouse Liver. Toxicol Sci. 2022 May 26; 187(2):298-310. PMID: 35285501.

    Read at: PubMed

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