David J. Waxman, PhD

Professor, Boston University

Biography

David J. Waxman, PhD is a Biologist with extensive experience in the fields of biochemistry, molecular biology, and enzymology. Over the past 35 years, his lab has made seminal contributions to the research of cancer pharmacology and therapeutics, and steroid-metabolizing enzymes. His current interests include genomic and epigenetic mechanisms controlling liver gene expression, molecular endocrinology and cell signaling through transcriptional networks, role of angiogenesis and innate immune system in cancer therapy and pharmacology, and nuclear receptors and responses to environmental chemicals.

Dr. Waxman has spoken at over 130 conferences and has held appointments at a variety of universities including Harvard Medical School, MIT, and the Weizmann Institute.

Publications

  • Published 12/24/2024

    Chang TY, Waxman DJ. HDI-STARR-seq: Condition-specific enhancer discovery in mouse liver in vivo. BMC Genomics. 2024 Dec 24; 25(1):1240. PMID: 39716078.

    Read at: PubMed

  • Published 9/25/2024

    Kineman RD, Del Rio-Moreno M, Waxman DJ. Liver-specific actions of GH and IGF1 that protect against MASLD. Nat Rev Endocrinol. 2025 Feb; 21(2):105-117. PMID: 39322791.

    Read at: PubMed

  • Published 8/1/2024

    Sonkar R, Ma H, Waxman DJ. Steatotic liver disease induced by TCPOBOP-activated hepatic constitutive androstane receptor: primary and secondary gene responses with links to disease progression. Toxicol Sci. 2024 Aug 01; 200(2):324-345. PMID: 38710495.

    Read at: PubMed

  • Published 6/26/2024

    Chang TY, Waxman DJ. HDI-STARR-seq: Condition-specific enhancer discovery in mouse liver in vivo. Res Sq. 2024 Jun 26. PMID: 38978599.

    Read at: PubMed

  • Published 6/12/2024

    Chang TY, Waxman DJ. HDI-STARR-seq: Condition-specific enhancer discovery in mouse liver in vivo. bioRxiv. 2024 Jun 12. PMID: 38915578.

    Read at: PubMed

Other Positions

  • Member, Genome Science Institute
    Boston University
  • Professor, Medicine
    Boston University Chobanian & Avedisian School of Medicine
  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University

Education

  • Harvard University, PhD
  • Harvard University, AM
  • Queens College, City University of New York, BA