Claudia L. Satizabal, PhD

Adjunct Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Prior to joining the Framingham Heart Study in 2013, Satizabal earned her doctorate degree, studying the relationship between inflammatory proteins and cerebrovascular and neurodegenerative MRI markers of abnormal brain aging in the French Three-City Study at the INSERM Neuro-Epidemiology laboratory of the Pierre and Marie Curie University in Paris. In 2007, she was awarded a two-year Utrecht Excellence Scholarship to pursue a master’s degree in epidemiology from Utrecht University. In addition to her work at BUSM and the FHS, Satizabal is actively involved in the neurology and cognitive working groups of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, where she leads projects investigating the genetic variation in fine motor speed, visual memory, and subcortical brain structures. She participates in several other international collaborations including the AD Cohorts Consortium and the replication phase of the AD sequencing project. She is currently investigating the impact of midlife obesity, as well as different dietary, inflammatory and neurotrophic biomarkers, in association with stroke, cognitive function, MRI markers of abnormal brain aging and dementia.

Publications

  • Published 4/1/2025

    Cao Y, Salvati LR, Chen J, Ragab A, Mez J, Satizabal CL, Alosco ML, Fang Y, Qiu WQ, Lunetta KL, Murabito JM, Doyle MF. The Association of Circulating Immune Cells with Cognitive Function, Brain Imaging, and Incident all-cause and Alzheimer's Dementia: The Framingham Offspring Study. J Gerontol A Biol Sci Med Sci. 2025 Apr 01. PMID: 40168089.

    Read at: PubMed

  • Published 4/1/2025

    Salardini A, Himali JJ, Abdullah MS, Chaudhari R, Young V, Zilli EM, McGrath ER, Gonzales MM, Thibault EG, Salinas J, Aparicio HJ, Himali D, Ghosh S, Buckley RF, Satizabal CL, Johnson KA, DeCarli C, Fakhri GE, Vasan RS, Beiser AS, Seshadri S. Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study. Alzheimers Dement. 2025 Apr; 21(4):e70179. PMID: 40271551.

    Read at: PubMed

  • Published 3/26/2025

    Melgarejo JD, Patil D, Charisis S, Vatcheva KP, Mejia-Arango S, Mena LJ, Satizabal CL, Gaona C, Silva E, Manusov E, Lee JH, Terwilliger JD, Gutierrez J, Seshadri S, Maestre GE. Baseline associations of office and ambulatory blood pressure monitoring with cognitive function and dementia prevalence. J Alzheimers Dis. 2025 Apr; 104(4):1064-1074. PMID: 40138432.

    Read at: PubMed

  • Published 1/1/2025

    Charisis S, Mourtzi N, Scott MR, Ntanasi E, Mamalaki E, Hatzimanolis A, Ramirez A, Lambert JC, Yannakoulia M, Kosmidis M, Dardiotis E, Hadjigeorgiou G, Sakka P, Satizabal CL, Beiser A, Yang Q, Georgakis M?, Seshadri S, Scarmeas N. Genetic predisposition to high circulating levels of interleukin 6 and risk for Alzheimer's disease. Discovery and replication. J Prev Alzheimers Dis. 2025 Jan; 12(1):100018. PMID: 39800457.

    Read at: PubMed

  • Published 12/30/2024

    Liu X, Maillard P, Barisano G, Caprihan A, Cen S, Shao X, Jann K, Ringman JM, Lu H, Arfanakis K, DeCarli CS, Gold BT, Seshadri S, Satizabal CL, Beiser AS, Habes M, Kramer JH, Stables L, Singh H, Helmer KG, Greenberg SM, Wang DJJ. MRI free water mediates the association between diffusion tensor image analysis along the perivascular space and executive function in four independent middle to aged cohorts. Alzheimers Dement. 2025 Feb; 21(2):e14453. PMID: 39740225.

    Read at: PubMed

View All 172 Publications:   View Full Profile in BUMC

Other Positions

  • Investigator
    Framingham Heart Study

Websites

Education

  • Pierre and Marie Curie University (Paris VI), PhD
  • Utrecht University, MSc
  • Universidad de Los Andes, BSc

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