Charlene Ong, MD, MPHS

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Charlene Ong, MD, MPHS, is an Assistant Professor of Neurology and Neurosurgery at Chobanian and Avedisian School of Medicine (BUSM), and clinical Neurointensivist at Boston Medical Center (BMC), and a lecturer at Harvard Medical School. She received her undergraduate degree at University of Pennsylvania, her MD at Columbia University and her Master's in Population Health Sciences at Washington University School of Medicine. Her research focuses on the development and validation of data-driven tools to support clinical decision making in patients with catastrophic neurologic injury including ischemic and hemorrhagic stroke, traumatic brain injury and anoxic brain injury. She receives support from the National Institute of Health through a K-award, and has also received foundational support from the American Brain Foundation, Philips-MIT, Peter-Paul Career Development Committee and Boston University Center for Translational Science Institute. Through machine learning methods, understudied physiologic biomarkers, and dynamic multimodal risk prediction methods, she aims to reduce morbidity and optimize treatment decision making in patients with acute neurologic disease.

Publications

  • Published 5/7/2025

    Du Y, Ong CJ. Reply to "Revolutionizing Neuroprognostication: The Enduring Value of Pupillary Reflexes Enhanced by Quantitative Pupillometry". Ann Neurol. 2025 May 07. PMID: 40331913.

    Read at: PubMed

  • Published 4/29/2025

    Veerapaneni D, Arunachalam Sakthiyendran N, Du Y, Mallinger LA, Reinert A, Yeon Kim S, Nguyen C, Daneshmand A, Abdalkader M, Mohammed S, Dupuis J, Sheth KN, Gilmore EJ, Greer D, Ong CJ. Early Pupil Abnormality Frequency Predicts Poor Outcomes and Enhances International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) Model Prognostication in Traumatic Brain Injury. Crit Care Explor. 2025 May 01; 7(5):e1257. PMID: 40299976.

    Read at: PubMed

  • Published 4/5/2025

    Song JJ, Stafford RA, Pohlmann JE, Kim ISY, Cheekati M, Dennison S, Brush B, Chatzidakis S, Huang Q, Smirnakis SM, Gilmore EJ, Mohammed S, Abdalkader M, Benjamin EJ, Dupuis J, Greer DM, Ong CJ. Later midline shift is associated with better post-hospitalization discharge status after large middle cerebral artery stroke. Sci Rep. 2025 Apr 05; 15(1):11738. PMID: 40188256.

    Read at: PubMed

  • Published 3/24/2025

    Hill CJ, Sykora CA, Schmugge S, Tate S, Cronin MFM, Sisto J, Mallinger LA, Reinert A, Stafford RA, Tao BS, Sakthiyendran NA, Nguyen K, Krishnaswamy A, Patil S, Al-Faraj A, Noviawaty I, Russo M, Pugsley B, Lee JW, Greer D, Shin M, Ong CJ. Eye movement detection using electrooculography and machine learning in cardiac arrest patients. Resuscitation. 2025 May; 210:110577. PMID: 40133167.

    Read at: PubMed

  • Published 2/19/2025

    Cobler-Lichter MJ, Suchdev K, Tatro H, Cascone A, Yang J, Weinberg J, Abdalkader MK, Dasenbrock HH, Ong CJ, Cervantes-Arslanian A, Greer D, Nguyen TN, Daneshmand A, Chung DY. Safety and Outcomes of Valproic Acid in Subarachnoid Hemorrhage Patients: A Retrospective Study. Clin Neuropharmacol. 2025 Mar-Apr 01; 48(2):43-50. PMID: 40035592.

    Read at: PubMed

View All 48 Publications:   View Full Profile in BUMC

Other Positions

  • Assistant Professor, Neurosurgery
    Boston University Chobanian & Avedisian School of Medicine
  • Visiting Scientist
    Massachusetts Institute of Technology

Websites

Education

  • Columbia University College of Physicians and Surgeons, MD
  • University of Pennsylvania, BA
  • University of Pennsylvania, BS

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