Charlene Ong, MD, MPHS
Assistant Professor, Neurology
Biography
Charlene Ong, MD, MPHS, is an Assistant Professor of Neurology and Neurosurgery at Chobanian and Avedisian School of Medicine (BUSM), and clinical Neurointensivist at Boston Medical Center (BMC), and a lecturer at Harvard Medical School. She received her undergraduate degree at University of Pennsylvania, her MD at Columbia University and her Master’s in Population Health Sciences at Washington University School of Medicine. Her research focuses on the development and validation of data-driven tools to support clinical decision making in patients with catastrophic neurologic injury including ischemic and hemorrhagic stroke, traumatic brain injury and anoxic brain injury. She receives support from the National Institute of Health through a K-award, and has also received foundational support from the American Brain Foundation, Philips-MIT, Peter-Paul Career Development Committee and Boston University Center for Translational Science Institute. Through machine learning methods, understudied physiologic biomarkers, and dynamic multimodal risk prediction methods, she aims to reduce morbidity and optimize treatment decision making in patients with acute neurologic disease.
Other Positions
- Assistant Professor, Neurosurgery, Boston University Chobanian & Avedisian School of Medicine
- Visiting Scientist, Massachusetts Institute of Technology
Education
- Columbia University College of Physicians and Surgeons, MD
- University of Pennsylvania, BA
- University of Pennsylvania, BS
Publications
- Published on 2/19/2025
Cobler-Lichter MJ, Suchdev K, Tatro H, Cascone A, Yang J, Weinberg J, Abdalkader MK, Dasenbrock HH, Ong CJ, Cervantes-Arslanian A, Greer D, Nguyen TN, Daneshmand A, Chung DY. Safety and Outcomes of Valproic Acid in Subarachnoid Hemorrhage Patients: A Retrospective Study. Clin Neuropharmacol. 2025 Mar-Apr 01; 48(2):43-50. PMID: 40035592.
Read at: PubMed - Published on 1/18/2025
Du Y, Pohlmann JE, Chatzidakis S, Brush B, Malinger LA, Stafford RA, Cervantes-Arslanian AM, Benjamin EJ, Gilmore EJ, Dupuis J, Greer DM, Smirnakis SM, Mohammed S, Ong CJ. Quantitative Pupillometry Predicts Neurologic Deterioration in Patients with Large Middle Cerebral Artery Stroke. Ann Neurol. 2025 May; 97(5):930-941. PMID: 39825740.
Read at: PubMed - Published on 12/26/2024
Stafford R, Chatzidakis S, Kim ISY, Zhang Y, Rina A, Brush B, Mian A, Abdalkader M, Greer DM, Smirnakis SM, Feske SK, Dupuis J, Ong CJ. Follow-up ASPECTS improves prediction of potentially lethal malignant edema in patients with large middle cerebral artery stroke. J Neurointerv Surg. 2024 Dec 26; 17(e1):e83-e86. PMID: 38160055.
Read at: PubMed - Published on 11/26/2024
Veerapaneni D, Sakthiyendran NA, Kim SY, Nguyen C, Daneshmand A, Abdalkader M, Mohammed S, Dupuis J, Sheth KN, Gilmore EJ, Greer D, Ong CJ. Pupil Abnormality Frequency in the First 72 Hours Improves IMPACT score in Traumatic Brain Injury. medRxiv. 2024 Nov 26. PMID: 39649617.
Read at: PubMed - Published on 11/13/2024
Phillips E, O'Donoghue O, Zhang Y, Tsimpos P, Mallinger LA, Chatzidakis S, Pohlmann J, Du Y, Kim I, Song J, Brush B, Smirnakis S, Ong CJ, Orfanoudaki A. HELMET: A Hybrid Machine Learning Framework for Real-Time Prediction of Edema Trajectory in Large Middle Cerebral Artery Stroke. medRxiv. 2024 Nov 13. PMID: 39606388.
Read at: PubMed - Published on 7/31/2024
Greige T, Tao BS, Dangayach NS, Gilmore EJ, O'Hana Nobleza C, Hinson HE, Chou SH, Jha RM, Wahlster S, Gebrewold MA, Lele AV, Ong CJ. Cerebral Edema Monitoring and Management Strategies: Results from an International Practice Survey. Neurocrit Care. 2025 Feb; 42(1):207-221. PMID: 39085504.
Read at: PubMed - Published on 7/2/2024
Ong CJ, Huang Q, Kim ISY, Pohlmann J, Chatzidakis S, Brush B, Zhang Y, Du Y, Malinger LA, Benjamin EJ, Dupuis J, Greer DM, Smirnakis SM, Trinquart L. Association of Dynamic Trajectories of Time-Series Data and Life-Threatening Mass Effect in Large Middle Cerebral Artery Stroke. Neurocrit Care. 2025 Feb; 42(1):77-89. PMID: 38955931.
Read at: PubMed - Published on 6/7/2024
Abdalkader M, Nguyen TN, Sahoo A, Qureshi MM, Ong CJ, Klein P, Miller MI, Mian AZ, Kaesmacher J, Mujanovic A, Hu W, Chen HS, Setty BN. Contrast Staining in Noninfarcted Tissue after Endovascular Treatment of Acute Ischemic Stroke. AJNR Am J Neuroradiol. 2024 Jun 07; 45(6):701-707. PMID: 38697792.
Read at: PubMed - Published on 5/17/2024
Ong CJ, Chatzidakis S, Ong JJ, Feske S. Updates in Management of Large Hemispheric Infarct. Semin Neurol. 2024 Jun; 44(3):281-297. PMID: 38759959.
Read at: PubMed - Published on 5/1/2024
Pohlmann JE, Kim ISY, Brush B, Sambhu KM, Conti L, Saglam H, Milos K, Yu L, Cronin MFM, Balogun O, Chatzidakis S, Zhang Y, Trinquart L, Huang Q, Smirnakis SM, Benjamin EJ, Dupuis J, Greer DM, Ong CJ. Association of large core middle cerebral artery stroke and hemorrhagic transformation with hospitalization outcomes. Sci Rep. 2024 May 01; 14(1):10008. PMID: 38693282.
Read at: PubMed
View 33 more publications: View full profile at BUMC