Charlene Ong, MD, MPHS

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Charlene Ong, MD, MPHS, is an Associate Professor of Neurology and Neurosurgery at Chobanian and Avedisian School of Medicine (BUSM), and clinical Neurointensivist at Boston Medical Center (BMC), and a lecturer at Harvard Medical School. She received her undergraduate degree at University of Pennsylvania, her MD at Columbia University and her Master's in Population Health Sciences at Washington University School of Medicine. Her research focuses on the development and validation of data-driven tools to support clinical decision making in patients with catastrophic neurologic injury including ischemic and hemorrhagic stroke, traumatic brain injury and anoxic brain injury. She receives support from the National Institute of Health, and has also received foundational support from the American Brain Foundation, Philips-MIT, Peter-Paul Career Development Committee, Hariri Institute, and Boston University Center for Translational Science Institute. Through machine learning methods, understudied physiologic biomarkers, and dynamic multimodal risk prediction methods, she aims to reduce morbidity and optimize treatment decision making in patients with acute neurologic disease.

Publications

  • Published 2/12/2026

    Madakasira SS, Stolarski AE, Saillant NN, Scantling DR, Sanchez SE, Ong CJ, Feldman J, Sperry JL, Torres CM. Whole Blood-Based Resuscitation and Mortality in Patients with Traumatic Intracranial Hemorrhage. J Am Coll Surg. 2026 Feb 12. PMID: 41677120.

    Read at: PubMed

  • Published 1/19/2026

    Stafford RA, Srivastava V, Altaf AZ, Mallinger LA, Reinert AL, Madipally SSK, Salvati LR, Wahlster S, Chen D, Gilmore EJ, Greer DM, Cheng H, Ong C. Automated Cerebral Edema Detection using Electroencephalography in Post-Cardiac Arrest Patients. Res Sq. 2026 Jan 19. PMID: 41646308.

    Read at: PubMed

  • Published 9/17/2025

    Du Y, Mallinger LA, Reinert AL, Chatzidakis S, Ibrahim NJ, Wirth G, Kumar A, Avula A, Cheng H, Greer DM, Dhar R, Ong C. Integrating Brain Imaging Volumetrics and Quantitative Pupillometry for Predicting Neurologic Deterioration after Large Hemispheric Stroke. Res Sq. 2025 Sep 17. PMID: 41001532.

    Read at: PubMed

  • Published 5/17/2025

    Phillips E, O'Donoghue O, Zhang Y, Tsimpos P, Mallinger LA, Chatzidakis S, Pohlmann J, Du Y, Kim I, Song J, Brush B, Smirnakis S, Ong CJ, Orfanoudaki A. Hybrid machine learning for real-time prediction of edema trajectory in large middle cerebral artery stroke. NPJ Digit Med. 2025 May 17; 8(1):288. PMID: 40379753.

    Read at: PubMed

  • Published 5/7/2025

    Du Y, Ong CJ. Reply to "Revolutionizing Neuroprognostication: The Enduring Value of Pupillary Reflexes Enhanced by Quantitative Pupillometry". Ann Neurol. 2025 Jul; 98(1):202. PMID: 40331913.

    Read at: PubMed

View All 56 Publications:   View Full Profile in BUMC

Other Positions

  • Assistant Professor, Neurosurgery
    Boston University Chobanian & Avedisian School of Medicine
  • Visiting Scientist
    Massachusetts Institute of Technology

Websites

Education

  • Columbia University College of Physicians and Surgeons, MD
  • University of Pennsylvania, BA
  • University of Pennsylvania, BS

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