Carlos J. Acuna-Villaorduna, MD

Adjunct Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Carlos Acuña-Villaorduña is an infectious disease specialist with interest in tuberculosis, tropical medicine, and mathematical modelling of infectious diseases. After finishing medical school, he worked as a researcher at the “Alexander Von Humboldt Tropical Medicine Institute” in Lima, Peru, the largest tropical medicine in South America, where he successfully collaborated in several research projects in tuberculosis epidemiology and diagnostics. After moving to the United States to complete his medical training, he earned a master degree in epidemiology at the “University of London”. He currently holds an appointment as Assistant Professor of Medicine at Boston University and provide care for patients at the tuberculosis clinic of Boston. Dr. Acuña-Villaorduña is interested in understanding the complex mechanisms leading to tuberculosis transmission in developing countries. His research focuses on investigating the ability of certain mycobacterial strains to survive in the environment and to produce infection and disease.

Publications

  • Published 7/27/2024

    Hamada Y, Quartagno M, Malik F, Ntshamane K, Tisler A, Gaikwad S, Acuna-Villaorduna C, Bhavani PK, Alisjahbana B, Ronacher K, Apriani L, Becerra M, Chu AL, Creswell J, Diaz G, Ferro BE, Galea JT, Grandjean L, Grewal HMS, Gupta A, Jones-López EC, Kleynhans L, Lecca L, MacPherson P, Murray M, Marín D, Restrepo BI, Shivakumar SVBY, Shu E, Sivakumaran D, Vo LNQ, Webb EL, Copas A, Abubakar I, Rangaka MX. Prevalence of non-communicable diseases among household contacts of people with tuberculosis: A systematic review and individual participant data meta-analysis. Trop Med Int Health. 2024 Sep; 29(9):768-780. PMID: 39073229.

    Read at: PubMed

  • Published 1/5/2023

    Hamada Y, Gupta RK, Quartagno M, Izzard A, Acuna-Villaorduna C, Altet N, Diel R, Dominguez J, Floyd S, Gupta A, Huerga H, Jones-López EC, Kinikar A, Lange C, van Leth F, Liu Q, Lu W, Lu P, Rueda IL, Martinez L, Mbandi SK, Muñoz L, Padilla ES, Paradkar M, Scriba T, Sester M, Shanaube K, Sharma SK, Sloot R, Sotgiu G, Thiruvengadam K, Vashishtha R, Abubakar I, Rangaka MX. Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis. EClinicalMedicine. 2023 Feb; 56:101815. PMID: 36636295.

    Read at: PubMed

  • Published 9/10/2022

    Sinha P, Lakshminarayanan SL, Cintron C, Narasimhan PB, Locks LM, Kulatilaka N, Maloomian K, Prakash Babu S, Carwile ME, Liu AF, Horsburgh CR, Acuna-Villaorduna C, Linas BP, Hochberg NS. Nutritional Supplementation Would Be Cost-Effective for Reducing Tuberculosis Incidence and Mortality in India: The Ration Optimization to Impede Tuberculosis (ROTI-TB) Model. Clin Infect Dis. 2022 Sep 10; 75(4):577-585. PMID: 34910141.

    Read at: PubMed

  • Published 9/1/2022

    Martinez L, Cords O, Liu Q, Acuna-Villaorduna C, Bonnet M, Fox GJ, Carvalho ACC, Chan PC, Croda J, Hill PC, Lopez-Varela E, Donkor S, Fielding K, Graham SM, Espinal MA, Kampmann B, Reingold A, Huerga H, Villalba JA, Grandjean L, Sotgiu G, Egere U, Singh S, Zhu L, Lienhardt C, Denholm JT, Seddon JA, Whalen CC, García-Basteiro AL, Triasih R, Chen C, Singh J, Huang LM, Sharma S, Hannoun D, Del Corral H, Mandalakas AM, Malone LL, Ling DL, Kritski A, Stein CM, Vashishtha R, Boulahbal F, Fang CT, Boom WH, Netto EM, Lemos AC, Hesseling AC, Kay A, Jones-López EC, Horsburgh CR, Lange C, Andrews JR. Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis. Lancet Glob Health. 2022 Sep; 10(9):e1307-e1316. PMID: 35961354.

    Read at: PubMed

  • Published 2/5/2022

    Dhanani M, Goodrich C, Weinberg J, Acuna-Villaorduna C, Barlam TF. Antibiotic therapy completion for injection drug use-associated infective endocarditis at a center with routine addiction medicine consultation: a retrospective cohort study. BMC Infect Dis. 2022 Feb 05; 22(1):128. PMID: 35123439.

    Read at: PubMed

Education

  • Universidad Peruana Cayetano Heredia, MD