Brigitte Ritter, PhD
Assistant Professor, Biochemistry & Cell Biology
Biography
Her research interests and expertise is in intracellular receptor sorting controls basic cellular functions such as nutrient uptake and signaling as well as complex behaviors such as migration, differentiation and tissue morphogenesis. Accordingly, the proteins and mechanisms involved in the various sorting pathways are key to normal cell physiology and their misregulation directly contributes to human disease.
Her laboratory focused on clathrin-mediated sorting events and the regulation of these events by the NECAP protein family.
Other Positions
- Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Education
- University of Cologne, PhD
Publications
- Published on 3/17/2022
Husein D, Alamoudi A, Ohyama Y, Mochida H, Ritter B, Mochida Y. Identification of the C-terminal region in Amelogenesis Imperfecta causative protein WDR72 required for Golgi localization. Sci Rep. 2022 03 17; 12(1):4640. PMID: 35301423.
Read at: PubMed - Published on 12/5/2017
Ritter B, Ferguson SM, De Camilli P, McPherson PS. A lentiviral system for efficient knockdown of proteins in neuronal cultures [version 1; referees: 2 approved]. MNI Open Res. 2017; 1(2). PMID: 29355247.
Read at: PubMed - Published on 10/23/2017
Chamberland JP, Ritter B. Retromer revisited: Evolving roles for retromer in endosomal sorting. J Cell Biol. 2017 11 06; 216(11):3433-3436. PMID: 29061649.
Read at: PubMed - Published on 5/20/2016
Chamberland JP, Antonow LT, Dias Santos M, Ritter B. NECAP2 controls clathrin coat recruitment to early endosomes for fast endocytic recycling. J Cell Sci. 2016 Jul 01; 129(13):2625-37. PMID: 27206861.
Read at: PubMed - Published on 8/20/2015
Rouka E, Simister PC, Janning M, Kumbrink J, Konstantinou T, Muniz JR, Joshi D, O'Reilly N, Volkmer R, Ritter B, Knapp S, von Delft F, Kirsch KH, Feller SM. Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3). J Biol Chem. 2015 Oct 16; 290(42):25275-92. PMID: 26296892.
Read at: PubMed - Published on 1/1/2015
Allaire PD, McPherson PS, Ritter B. Analysis of connecdenn 1-3 (DENN1A-C) GEF activity for Rab35. Methods Mol Biol. 2015; 1298:217-31. PMID: 25800846.
Read at: PubMed - Published on 6/24/2014
Wu Y, O'Toole ET, Girard M, Ritter B, Messa M, Liu X, McPherson PS, Ferguson SM, De Camilli P. A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis. Elife. 2014; 3:e01621. PMID: 24963135.
Read at: PubMed - Published on 10/1/2013
Ritter B, Murphy S, Dokainish H, Girard M, Gudheti MV, Kozlov G, Halin M, Philie J, Jorgensen EM, Gehring K, McPherson PS. NECAP 1 regulates AP-2 interactions to control vesicle size, number, and cargo during clathrin-mediated endocytosis. PLoS Biol. 2013 Oct; 11(10):e1001670. PMID: 24130457.
Read at: PubMed - Published on 12/21/2012
Allaire PD, Seyed Sadr M, Chaineau M, Seyed Sadr E, Konefal S, Fotouhi M, Maret D, Ritter B, Del Maestro RF, McPherson PS. Interplay between Rab35 and Arf6 controls cargo recycling to coordinate cell adhesion and migration. J Cell Sci. 2013 Feb 1; 126(Pt 3):722-31. PMID: 23264734.
Read at: PubMed - Published on 10/20/2010
Kent CB, Shimada T, Ferraro GB, Ritter B, Yam PT, McPherson PS, Charron F, Kennedy TE, Fournier AE. 14-3-3 proteins regulate protein kinase a activity to modulate growth cone turning responses. J Neurosci. 2010 Oct 20; 30(42):14059-67. PMID: 20962227.
Read at: PubMed
View 18 more publications: View full profile at BUMC