Alyssa S. Tilhou, MD, PhD

Assistant Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Tilhou is a family physician, addiction specialist and health services researcher in the Department of Family Medicine at Boston Medical Center. She is also the department's Research Director. Her research focuses on access and utilization of primary care and substance use services in low-income populations. Dr. Tilhou completed her medical education and doctorate in Population Health Sciences at the University of Texas Medical Branch, residency in family medicine at the Mountain Area Health Education Center in Asheville, NC, and a fellowship in Addiction Medicine at the University of Wisconsin. She is supported by a K08 from the National Institute on Drug Abuse. Other recent funding includes a BU CTSI pilot award to study disparities in buprenorphine quality indicators among BMC patients and a contract with the Wisconsin Department of Health Services to evaluate the impact of a Section 1115 waiver on health care utilization and outcomes among Medicaid beneficiaries.

Publications

  • Published 7/1/2026

    Hsu HE, Lodi S, Yan S, Bovell-Ammon BJ, Christine PJ, Tilhou AS, Bernson D, Novo P, Lee JD, Rotrosen J, Liebschutz JM, Walley AY, Larochelle MR. Buprenorphine-Naloxone vs Extended-Release Naltrexone Following Opioid Withdrawal Treatment. JAMA Netw Open. 2026 Jul 01; 9(7):e2623280. PMID: 42446876.

    Read at: PubMed

  • Published 4/20/2026

    Tilhou AS, Wang J, George ST, White L, Assoumou SA. HIV pre-exposure prophylaxis among people initiating buprenorphine for opioid use disorder in the ambulatory setting: A retrospective cohort study. Drug Alcohol Depend. 2026 Jul 01; 284:113164. PMID: 42066527.

    Read at: PubMed

  • Published 3/25/2026

    Tilhou AS, Cameron C, Alves J, Baldwin MC, Farrell NM, Hudson M. Managing acute stimulant intoxication in ambulatory settings: a protocol-driven case report. Am J Drug Alcohol Abuse. 2026; 52(2):199-206. PMID: 41879470.

    Read at: PubMed

  • Published 2/10/2026

    Leyde S, Tilhou AS, Tsui JI. Treatment of Methamphetamine Use Disorder-Reply. JAMA. 2026 Feb 10; 335(6):551. PMID: 41525062.

    Read at: PubMed

  • Published 10/7/2025

    Leyde S, Tilhou AS, Tsui JI. Methamphetamine Use Disorder. JAMA. 2025 Oct 07; 334(13):1192-1193. PMID: 40900575.

    Read at: PubMed

View All 26 Publications:   View Full Profile in BUMC

Websites

Education

  • Harvard University, AB
  • University of Texas Medical Branch, MD/PhD

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