Alpaslan Dedeoglu, MD, PhD

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Alpaslan Dedeoglu received his MD from the Istanbul University School of Medicine and completed a pharmacology program at the Marmara University in 1992. During and after his pharmacology program he worked at the University of Arizona, Ohio State University, and Massachusetts General Hospital; he then joined Boston University in 2000. Dr. Dedeoglu’s major research interests are neuroanatomy, neuropathology, and the neurochemistry of animal models of neurodegenerative disorders. His labs are located at the Boston VA Medical Center. Dr. Dedeoglu is the PI of several ongoing projects that are funded by the NIH, VA, and private foundations. He also works with therapeutic trials in rodent models of neurodegenerative disorders.

Publications

  • Published 4/28/2024

    Jung Y, Ay B, Cyr SM, Tognoni CM, Klovdahl K, Matthias J, Cui Q, Brooks DJ, Bouxsein ML, Carreras I, Dedeoglu A, Bastepe M. Amyloid-ß neuropathology induces bone loss in male mice by suppressing bone formation and enhancing bone resorption. Bone Rep. 2024 Jun; 21:101771. PMID: 38725879.

    Read at: PubMed

  • Published 3/26/2024

    Ay B, Cyr SM, Klovdahl K, Zhou W, Tognoni CM, Iwasaki Y, Rhee EP, Dedeoglu A, Simic P, Bastepe M. Ga11 deficiency increases fibroblast growth factor 23 levels in a mouse model of familial hypocalciuric hypercalcemia. JCI Insight. 2024 Mar 26; 9(9). PMID: 38530370.

    Read at: PubMed

  • Published 6/14/2023

    Almarhoumi R, Alvarez C, Harris T, Tognoni CM, Paster BJ, Carreras I, Dedeoglu A, Kantarci A. Microglial cell response to experimental periodontal disease. J Neuroinflammation. 2023 Jun 14; 20(1):142. PMID: 37316834.

    Read at: PubMed

  • Published 5/7/2023

    Carreras I, Jung Y, Lopez-Benitez J, Tognoni CM, Dedeoglu A. Fingolimod mitigates memory loss in a mouse model of Gulf War Illness amid decreasing the activation of microglia, protein kinase R, and NF?B. Neurotoxicology. 2023 May; 96:197-206. PMID: 37160207.

    Read at: PubMed

  • Published 11/18/2022

    Jung Y, Lopez-Benitez J, Tognoni CM, Carreras I, Dedeoglu A. Dysregulation of sphingosine-1-phosphate (S1P) and S1P receptor 1 signaling in the 5xFAD mouse model of Alzheimer's disease. Brain Res. 2023 Jan 15; 1799:148171. PMID: 36410428.

    Read at: PubMed

View All 58 Publications:   View Full Profile in BUMC

Other Positions

  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Websites

Education

  • Istanbul University, MD
  • Marmara University, PhD

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