Vladimir A. Botchkarev, MD, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Vladimir Botchkarev, MD, PhD is Research Associate Professor in the Department of Dermatology. He received his medical training at Chuvash State University in Cheboksary, Russian and his doctoral training at People’s Friendship University in Moscow, Russia. He was a recipient of the Research Career Development Award from the Dermatology Foundation and Independent Scientist Award from the National Institutes of Health. He is also a recipient of the research grants from the NIAMS and NCI. His name was included in the books 2000 Outstanding Scientists of the 21st Century, Great Minds of the 21st Century and Who is Who in Medicine. His primary research interests are the molecular mechanisms of hair growth and pathobiology of different forms of hair loss.

Publications

  • Published 8/21/2026

    Fatima I, Mardaryev AN, Rozhkova E, Botchkareva NV, Sharov AA, Botchkarev VA. Intrinsic anti-tumorigenic properties of the skin epithelium promote cancer resistance in naked mole-rats. iScience. 2026 Sep 18; 29(9):117262. PMID: 42668625.

    Read at: PubMed

  • Published 10/31/2025

    Athar F, Morandini F, Fatima I, Silvestri I, Kim SJ, Lee M, Liao X, Sharov A, Botchkarev V, Seluanov A, Gorbunova V. African spiny mice show resistance to DMBA/TPA-induced squamous carcinogenesis with distinct benign tumor profile. Protein Cell. 2025 Oct 31; 16(10):896-904. PMID: 40119780.

    Read at: PubMed

  • Published 10/2/2025

    Kohwi Y, Wong X, Grange M, Sexton T, Richards HW, Kitagawa Y, Sakaguchi S, Liang YC, Chuong CM, Botchkarev VA, Taniuchi I, Reddy KL, Kohwi-Shigematsu T. Genome organization by SATB1 binding to base-unpairing regions (BURs) provides a scaffold for SATB1-regulated gene expression. Elife. 2025 Oct 02; 14. PMID: 41036778.

    Read at: PubMed

  • Published 4/11/2023

    Botchkarev VA, Fessing MY, Sharov AA. Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation. J Invest Dermatol. 2023 Jul; 143(7):1117-1120. PMID: 37045617.

    Read at: PubMed

  • Published 1/11/2023

    Chen GD, Fatima I, Xu Q, Rozhkova E, Fessing MY, Mardaryev AN, Sharov AA, Xu GL, Botchkarev VA. DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation. Sci Adv. 2023 Jan 13; 9(2):eabo7605. PMID: 36630508.

    Read at: PubMed

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Other Positions

  • Graduate Medical Sciences Educator and Mentor (Primary Mentor of Graduate Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
  • Adjunct Professor, Pathology & Laboratory Medicine
    Boston University Chobanian & Avedisian School of Medicine

Websites

Education

  • Chuvash State University, MD
  • Peoples' Friendship University of Russia, PhD

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