Victor E. Alvarez

Assistant Professor, Neurology

Victor Alvarez
781.687.3393

Biography

Dr. Alvarez completed his undergraduate degree at Boston College and earned his MD from St. George’s University. He completed residency training in Anatomic and Clinical Pathology at the University of Rochester School of Medicine, fellowship training in Oncologic Surgical Pathology at Roswell Park Cancer Institute, General Surgical Pathology fellowship training at Danbury Hospital, and Neuropathology fellowship training at Brown University. Dr. Alvarez is an Assistant Professor of Neurology at Boston University and manages laboratory and Brain Bank operations at the Bedford VA Hospital and the Boston VA Hospital, Jamaica Plain. He is a member of the New England Veterans Administration Medical Centers (VISN-1) Brain Banks and the Brain Banks for the Boston University Alzheimer’s Disease Center, Center for the Study of Traumatic Encephalopathy, and Framingham Heart Study.

Dr. Alvarez’s research interests center on the relationship between neurotrauma and neurodegenerative diseases. Much of his current work centers on standardizing Brain Banking protocols between the various centers. He is an acting neuropathologist involved with the brain banks for the Boston University Alzheimer Disease Center, CTE Center, and Framingham Heart Study as well as the PTSD brain bank. Dr. Alvarez is a member of the College of American Pathologists and the American Society of Clinical Pathologists.

Other Positions

  • Investigator, Framingham Heart Study
  • Investigator, Alzheimer's Disease Center, Boston University
  • Investigator, Chronic Traumatic Encephalopathy Center, Boston University School of Medicine
  • Investigator, PTSD Brain Bank, VA Healthcare System

Publications

  • Published on 2/21/2022

    Moncaster JA, Moir RD, Burton MA, Chadwick O, Minaeva O, Alvarez VE, Ericsson M, Clark JI, McKee AC, Tanzi RE, Goldstein LE. Alzheimer's disease amyloid-ß pathology in the lens of the eye. Exp Eye Res. 2022 Feb 21; 108974. PMID: 35202705.

    Read at: PubMed
  • Published on 2/9/2022

    Turk KW, Geada A, Alvarez VE, Xia W, Cherry JD, Nicks R, Meng G, Daley S, Tripodis Y, Huber BR, Budson AE, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, Alosco ML, Mez J, McKee AC, Stein TD. A comparison between tau and amyloid-ß cerebrospinal fluid biomarkers in chronic traumatic encephalopathy and Alzheimer disease. Alzheimers Res Ther. 2022 02 09; 14(1):28. PMID: 35139894.

    Read at: PubMed
  • Published on 12/7/2021

    Alosco ML, Mian AZ, Buch K, Farris CW, Uretsky M, Tripodis Y, Baucom Z, Martin B, Palmisano J, Puzo C, Ang TFA, Joshi P, Goldstein LE, Au R, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Huber BR, Alvarez VE, Stern RA, Stein TD, Killiany RJ, McKee AC, Mez J. Structural MRI profiles and tau correlates of atrophy in autopsy-confirmed CTE. Alzheimers Res Ther. 2021 12 07; 13(1):193. PMID: 34876229.

    Read at: PubMed
  • Published on 12/2/2021

    Stathas S, Alvarez VE, Xia W, Nicks R, Meng G, Daley S, Pothast M, Shah A, Kelley H, Esnault C, McCormack R, Dixon E, Fishbein L, Cherry JD, Huber BR, Tripodis Y, Alosco ML, Mez J, McKee AC, Stein TD. Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease. Alzheimers Dement. 2021 Dec 02. PMID: 34854540.

    Read at: PubMed
  • Published on 11/24/2021

    Uretsky M, Bouix S, Killiany RJ, Tripodis Y, Martin B, Palmisano J, Mian AZ, Buch K, Farris C, Daneshvar DH, Dwyer B, Goldstein L, Katz D, Nowinski C, Cantu R, Kowall N, Huber BR, Stern RA, Alvarez VE, Stein TD, McKee A, Mez J, Alosco ML. Association Between Antemortem FLAIR White Matter Hyperintensities and Neuropathology in Brain Donors Exposed to Repetitive Head Impacts. Neurology. 2022 01 04; 98(1):e27-e39. PMID: 34819338.

    Read at: PubMed
  • Published on 8/27/2021

    Jiang L, Lin W, Zhang C, Ash PEA, Verma M, Kwan J, van Vliet E, Yang Z, Cruz AL, Boudeau S, Maziuk BF, Lei S, Song J, Alvarez VE, Hovde S, Abisambra JF, Kuo MH, Kanaan N, Murray ME, Crary JF, Zhao J, Cheng JX, Petrucelli L, Li H, Emili A, Wolozin B. Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy. Mol Cell. 2021 10 21; 81(20):4209-4227.e12. PMID: 34453888.

    Read at: PubMed
  • Published on 8/17/2021

    Cherry JD, Agus F, Dixon E, Huber B, Alvarez VE, Mez J, McKee AC, Labadorf A, Stein TD. Differential gene expression in the cortical sulcus compared to the gyral crest within the early stages of chronic traumatic encephalopathy. Free Neuropathol. 2021; 2. PMID: 34485990.

    Read at: PubMed
  • Published on 7/1/2021

    Hugo Montes A, Valle-Garay E, Martin G, Collazos J, Alvarez V, Meana A, Pérez-Is L, Carton JA, Taboada F, Asensi V. The TNF-a (-238 G/A) polymorphism could protect against development of severe sepsis. Innate Immun. 2021 07; 27(5):409-420. PMID: 34472396.

    Read at: PubMed
  • Published on 6/25/2021

    Gutierrez-Quiceno L, Dammer EB, Johnson AG, Webster JA, Shah R, Duong D, Yin L, Seyfried NT, Alvarez VE, Stein TD, McKee AC, Hales CM. A proteomic network approach resolves stage-specific molecular phenotypes in chronic traumatic encephalopathy. Mol Neurodegener. 2021 06 25; 16(1):40. PMID: 34172091.

    Read at: PubMed
  • Published on 5/21/2021

    Chancellor KB, Chancellor SE, Duke-Cohan JE, Huber BR, Stein TD, Alvarez VE, Okaty BW, Dymecki SM, McKee AC. Altered oligodendroglia and astroglia in chronic traumatic encephalopathy. Acta Neuropathol. 2021 08; 142(2):295-321. PMID: 34019156.

    Read at: PubMed

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