Dr. Alvarez completed his undergraduate degree at Boston College and earned his MD from St. George’s University. He completed residency training in Anatomic and Clinical Pathology at the University of Rochester School of Medicine, fellowship training in Oncologic Surgical Pathology at Roswell Park Cancer Institute, General Surgical Pathology at Danbury Hospital, and Neuropathology fellowship training at Brown University. Dr. Alvarez is an Assistant Professor of Neurology at Boston University and manages laboratory operations at the Bedford VA Hospital and the Jamaica Plain Veterans Administration. He is a member of the New England Veterans Administration Medical Centers (VISN-1) Brain Banks and the Brain Banks for the Boston University Alzheimer’s Disease Center, Center for the Study of Traumatic Encephalopathy, and Framingham Heart Study.
Dr. Alvarez’s research interests center on the relationship between neurotrauma and neurodegenerative diseases. Much of his current work centers on standardizing brain banking protocols between the various centers. He is an acting neuropathologist involved with the brain banks for the Boston University Alzheimer Disease Center, CTE Center, and Framingham Heart Study as well as the PTSD brain bank.
- Published on 11/26/2019
Minaeva O, Hua N, Franz ES, Lupoli N, Mian AZ, Farris CW, Hildebrandt AM, Kiernan PT, Evers LE, Griffin AD, Liu X, Chancellor SE, Babcock KJ, Moncaster JA, Jara H, Alvarez VE, Huber BR, Guermazi A, Latour LL, McKee AC, Soto JA, Anderson SW, Goldstein LE. Nonhomogeneous Gadolinium Retention in the Cerebral Cortex after Intravenous Administration of Gadolinium-based Contrast Agent in Rats and Humans. Radiology. 2019 Nov 26; 190461. PMID: 31769744.
- Published on 11/23/2019
Mez J, Daneshvar DH, Abdolmohammadi B, Chua AS, Alosco ML, Kiernan PT, Evers L, Marshall L, Martin BM, Palmisano JN, Nowinski CJ, Mahar I, Cherry JD, Alvarez VE, Dwyer B, Huber BR, Stein TD, Goldstein LE, Katz DI, Cantu RC, Au R, Kowall NW, Stern RA, McClean MD, Weuve J, Tripodis Y, McKee AC. Duration of American Football Play and Chronic Traumatic Encephalopathy. Ann Neurol. 2020 Jan; 87(1):116-131. PMID: 31589352.
- Published on 11/5/2019
Conner SC, Pase MP, Carneiro H, Raman MR, McKee AC, Alvarez VE, Walker JM, Satizabal CL, Himali JJ, Stein TD, Beiser A, Seshadri S. Mid-life and late-life vascular risk factor burden and neuropathology in old age. Ann Clin Transl Neurol. 2019 Dec; 6(12):2403-2412. PMID: 31691546.
- Published on 10/28/2019
Marquié M, Agüero C, Amaral AC, Villarejo-Galende A, Ramanan P, Chong MST, Sáez-Calveras N, Bennett RE, Verwer EE, Kim SJW, Dhaynaut M, Alvarez VE, Johnson KA, McKee AC, Frosch MP, Gómez-Isla T. [18F]-AV-1451 binding profile in chronic traumatic encephalopathy: a postmortem case series. Acta Neuropathol Commun. 2019 Oct 28; 7(1):164. PMID: 31661038.
- Published on 8/5/2019
Alosco ML, Stein TD, Tripodis Y, Chua AS, Kowall NW, Huber BR, Goldstein LE, Cantu RC, Katz DI, Palmisano JN, Martin B, Cherry JD, Mahar I, Killiany RJ, McClean MD, Au R, Alvarez V, Stern RA, Mez J, McKee AC. Association of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy. JAMA Neurol. 2019 Aug 05. PMID: 31380975.
- Published on 6/10/2019
Standring OJ, Friedberg J, Tripodis Y, Chua AS, Cherry JD, Alvarez VE, Huber BR, Xia W, Mez J, Alosco ML, Nicks R, Mahar I, Pothast MJ, Gardner HM, Meng G, Palmisano JN, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, McKee AC, Stein TD. Contact sport participation and chronic traumatic encephalopathy are associated with altered severity and distribution of cerebral amyloid angiopathy. Acta Neuropathol. 2019 Sep; 138(3):401-413. PMID: 31183671.
- Published on 12/18/2018
Nemani SK, Notari S, Cali I, Alvarez VE, Kofskey D, Cohen M, Stern RA, Appleby B, Abrams J, Schonberger L, McKee A, Gambetti P. Co-occurrence of chronic traumatic encephalopathy and prion disease. Acta Neuropathol Commun. 2018 12 18; 6(1):140. PMID: 30563563.
- Published on 12/18/2018
Armstrong RA, McKee AC, Stein TD, Alvarez VE, Cairns NJ. Cortical degeneration in chronic traumatic encephalopathy and Alzheimer's disease neuropathologic change. Neurol Sci. 2019 Mar; 40(3):529-533. PMID: 30564964.
- Published on 12/1/2018
Walt GS, Burris HM, Brady CB, Spencer KR, Alvarez VE, Huber BR, Guilderson L, Abdul Rauf N, Collins D, Singh T, Mathias R, Averill JG, Walker SE, Robey I, McKee AC, Kowall NW, Stein TD. Chronic Traumatic Encephalopathy Within an Amyotrophic Lateral Sclerosis Brain Bank Cohort. J Neuropathol Exp Neurol. 2018 12 01; 77(12):1091-1100. PMID: 30299493.
- Published on 11/4/2018
Cherry JD, Mez J, Crary JF, Tripodis Y, Alvarez VE, Mahar I, Huber BR, Alosco ML, Nicks R, Abdolmohammadi B, Kiernan PT, Evers L, Svirsky S, Babcock K, Gardner HM, Meng G, Nowinski CJ, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, Farrer LA, McKee AC, Stein TD. Variation in TMEM106B in chronic traumatic encephalopathy. Acta Neuropathol Commun. 2018 11 04; 6(1):115. PMID: 30390709.
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