Vanessa Xanthakis, PhD

Assistant Professor, Biostatistics

Vanessa Xanthakis
801 Massachusetts Ave Crosstown Center


Dr. Vanessa Xanthakis is a biostatistician with training in applied mathematics and statistics, and have a strong commitment to clinical epidemiological research. Presently, she is an Assistant Professor in the Section of Preventive Medicine and Epidemiology in the Department of Medicine at Boston University School of Medicine and in the Biostatistics Department at Boston University School of Public Health. At the Framingham Heart Study, she is a junior investigator and serve as the biostatistician on several investigations. For the last 8 years, Dr. Vanessa had focused her research on

A) the epidemiology of cardiac remodeling and subclinical disease, including identifying cardiovascular disease risk factors;

B) population-based vascular testing and echocardiography, including identifying biological, environmental, and genetic determinants (correlates) of cardiac structure and function;

C) epidemiology of novel biomarkers including but not limited to natriuretic peptides, adipokines, and vascular growth factors;

D) cardiovascular risk prediction using biomarkers and assessing their incremental prognostic utility (focus of her PhD thesis);

E) epidemiology of heart failure and its precursors; and

F) ideal cardiovascular health and its impact on cardiovascular disease and its precursors.

Other Positions

  • Assistant Professor, Preventive Medicine & Epidemiology, Medicine, Boston University School of Medicine
  • Investigator, Framingham Heart Study
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University


  • Boston University School of Public Health, PhD
  • University of Athens, MS
  • University of Athens, BS


  • Published on 7/20/2020

    Peloso GM, Beiser AS, Satizabal CL, Xanthakis V, Vasan RS, Pase MP, Destefano AL, Seshadri S. Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study. Neurology. 2020 Sep 08; 95(10):e1341-e1350. PMID: 32690788.

    Read at: PubMed
  • Published on 6/26/2020

    Schwedhelm E, Song RJ, Vasan RS, van den Heuvel ER, Hannemann J, Xanthakis V, Böger R. Association of Lower Plasma Homoarginine Concentrations with Greater Risk of All-Cause Mortality in the Community: The Framingham Offspring Study. J Clin Med. 2020 Jun 26; 9(6). PMID: 32604958.

    Read at: PubMed
  • Published on 6/25/2020

    Raunsø J, Song RJ, Vasan RS, Bourdillon MT, Nørager B, Torp-Pedersen C, Gislason GH, Xanthakis V, Andersson C. Familial Clustering of Aortic Size, Aneurysms, and Dissections in the Community. Circulation. 2020 Jun 25. PMID: 32580567.

    Read at: PubMed
  • Published on 6/15/2020

    Lee J, Walker ME, Gabriel KP, Vasan RS, Xanthakis V. Associations of accelerometer-measured physical activity and sedentary time with chronic kidney disease: The Framingham Heart Study. PLoS One. 2020; 15(6):e0234825. PMID: 32542048.

    Read at: PubMed
  • Published on 6/1/2020

    Lee J, Song RJ, Vasan RS, Xanthakis V. Association of Cardiorespiratory Fitness and Hemodynamic Responses to Submaximal Exercise Testing With the Incidence of Chronic Kidney Disease: The Framingham Heart Study. Mayo Clin Proc. 2020 Jun; 95(6):1184-1194. PMID: 32498774.

    Read at: PubMed
  • Published on 5/20/2020

    Lee J, Vasan RS, Xanthakis V. Association of Blood Pressure Responses to Submaximal Exercise in Midlife With the Incidence of Cardiovascular Outcomes and All-Cause Mortality: The Framingham Heart Study. J Am Heart Assoc. 2020 Jun 02; 9(11):e015554. PMID: 32431193.

    Read at: PubMed
  • Published on 5/19/2020

    Walker ME, Song RJ, Xu X, Gerszten RE, Ngo D, Clish CB, Corlin L, Ma J, Xanthakis V, Jacques PF, Vasan RS. Proteomic and Metabolomic Correlates of Healthy Dietary Patterns: The Framingham Heart Study. Nutrients. 2020 May 19; 12(5). PMID: 32438708.

    Read at: PubMed
  • Published on 5/15/2020

    Castro-Diehl C, Song RJ, Mitchell GF, McManus D, Cheng S, Vasan RS, Xanthakis V. Association of subclinical atherosclerosis with echocardiographic indices of cardiac remodeling: The Framingham Study. PLoS One. 2020; 15(5):e0233321. PMID: 32413074.

    Read at: PubMed
  • Published on 5/4/2020

    Nayor M, Xanthakis V, Tanguay M, Blodgett JB, Shah RV, Schoenike M, Sbarbaro J, Farrell R, Malhotra R, Houstis NE, Velagaleti RS, Moore SA, Baggish AL, O'Connor GT, Ho JE, Larson MG, Vasan RS, Lewis GD. Clinical and Hemodynamic Associations and Prognostic Implications of Ventilatory Efficiency in Patients With Preserved Left Ventricular Systolic Function. Circ Heart Fail. 2020 May; 13(5):e006729. PMID: 32362167.

    Read at: PubMed
  • Published on 3/11/2020

    Corlin L, Short MI, Vasan RS, Xanthakis V. Association of the Duration of Ideal Cardiovascular Health Through Adulthood With Cardiometabolic Outcomes and Mortality in the Framingham Offspring Study. JAMA Cardiol. 2020 Mar 11. PMID: 32159731.

    Read at: PubMed

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