Valerie Gouon-Evans, PhD, PharmD
Associate Professor, Medicine
Biography
Valerie Gouon-Evans, PharmD, PhD is an Associate Professor of Medicine in the department of Gastroenterology at the Chobanian and Avedisian School of Medicine. After completing her graduate studies in Paris, Dr. Gouon-Evans joined Dr. Pollard’s Lab as a postdoctoral fellow where she studied mammary gland development and breast cancer. She then began her career as an Instructor of Gene and Cell Medicine at the Icahn School of Medicine at Mount Sinai School of Medicine in New York in the laboratory of Dr. Gordon Keller, where she pioneered protocols to efficiently generate hepatocyte-like cells from pluripotent stem cells. She quickly rose up the ranks and was promoted to Assistant Professor before arriving at Boston University. Dr. Gouon-Evans’s current research interests range from liver development, regeneration, and cancer using the pluripotent stem cell platform, in vivo mouse models, and primary human tissues.
Other Positions
- Member, Center for Regenerative Medicine, Boston University
- Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
- Member, Genome Science Institute, Boston University
- Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Education
- University of Paris Vii, PhD
- Université Paris 5 René Descartes, PharmD
- University of Paris Vii, MS
- Pierre and Marie Curie University (Paris VI), BS
Publications
- Published on 4/7/2022
Smith AR, Gouon-Evans V. c-Maf: The magic wand that turns on LSEC fate. Cell Stem Cell. 2022 Apr 07; 29(4):491-493. PMID: 35395181.
Read at: PubMed - Published on 10/5/2021
Everton E, Rizvi F, Smith AR, Beattie M, Tam Y, Pardi N, Weissman D, Gouon-Evans V. Transient yet Robust Expression of Proteins in the Mouse Liver via Intravenous Injection of Lipid Nanoparticle-encapsulated Nucleoside-modified mRNA. Bio Protoc. 2021 Oct 05; 11(19):e4184. PMID: 34722830.
Read at: PubMed - Published on 5/10/2021
Rizvi F, Everton E, Smith AR, Liu H, Osota E, Beattie M, Tam Y, Pardi N, Weissman D, Gouon-Evans V. Author Correction: Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA. Nat Commun. 2021 May 10; 12(1):2825. PMID: 33972545.
Read at: PubMed - Published on 1/27/2021
Rizvi F, Everton E, Smith AR, Liu H, Osota E, Beattie M, Tam Y, Pardi N, Weissman D, Gouon-Evans V. Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA. Nat Commun. 2021 01 27; 12(1):613. PMID: 33504774.
Read at: PubMed - Published on 6/21/2018
Han S, Tan C, Ding J, Wang J, Ma'ayan A, Gouon-Evans V. Endothelial cells instruct liver specification of embryonic stem cell-derived endoderm through endothelial VEGFR2 signaling and endoderm epigenetic modifications. Stem Cell Res. 2018 07; 30:163-170. PMID: 29936335.
Read at: PubMed - Published on 2/14/2017
Bardot E, Calderon D, Santoriello F, Han S, Cheung K, Jadhav B, Burtscher I, Artap S, Jain R, Epstein J, Lickert H, Gouon-Evans V, Sharp AJ, Dubois NC. Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential. Nat Commun. 2017 02 14; 8:14428. PMID: 28195173.
Read at: PubMed - Published on 8/9/2016
Goldman O, Cohen I, Gouon-Evans V. Functional Blood Progenitor Markers in Developing Human Liver Progenitors. Stem Cell Reports. 2016 08 09; 7(2):158-66. PMID: 27509132.
Read at: PubMed - Published on 6/2/2016
Goldman O, Gouon-Evans V. Human Pluripotent Stem Cells: Myths and Future Realities for Liver Cell Therapy. Cell Stem Cell. 2016 06 02; 18(6):703-6. PMID: 27257759.
Read at: PubMed - Published on 5/21/2016
Goldman O, Valdes VJ, Ezhkova E, Gouon-Evans V. The mesenchymal transcription factor SNAI-1 instructs human liver specification. Stem Cell Res. 2016 07; 17(1):62-8. PMID: 27240252.
Read at: PubMed - Published on 6/15/2015
Gordillo M, Evans T, Gouon-Evans V. Orchestrating liver development. Development. 2015 Jun 15; 142(12):2094-108. PMID: 26081571.
Read at: PubMed
View 23 more publications: View full profile at BUMC