I am a rheumatologist and epidemiologist whose research has focused primarily on risk factors for knee osteoarthritis and gout, pain mechanisms in knee osteoarthritis, as well as methodologic issues of relevance for rheumatic diseases. I have had continuous peer-reviewed foundation and NIH funding since 2003, and have over 190 peer-reviewed publications to date. I am the most recent past chair of the FDA Arthritis Advisory Committee, serve on the boards two international societies: Osteoarthritis Research Society International (OARSI) and Gout, Hyperuricemia, and Crystal-Associated Diseases Network (G-CAN), and on committees for the American College of Rheumatology (ACR) and International Association for the Study Pain (IASP), among others. My work has been recognized with the prestigious 2014 ACR Henry Kunkel Young Investigator Award for outstanding and promising independent contributions to rheumatology research (awarded to no more than one clinical researcher and/or one basic science researcher each year). I have also engaged in developing new classification criteria for a number of rheumatic diseases. In addition to research, clinical work, and teaching, one of my key roles is to mentor trainees and junior faculty in musculoskeletal disease-related research. To that end, I was awarded the 2016 Robert Dawson Evans Research Mentoring Award. I am also leading the new CTSI Research Career Support Program initiative, PRIME (Pathways to Research Independence and Mentoring Excellence), which aims to support early career mentored researchers to successfully transition to becoming independent researchers.
– Osteoarthritis: epidemiology; risk factors; mechanisms of osteoarthritis-related pain; the role of bone in the pathophysiology of osteoarthritis
– Gout: epidemiology; risk factors and triggers for gout attacks; management of gout; consequences of gout and hyperuricemia
– Classification criteria and outcome measures in rheumatic diseases.
– Novel methodology to address challenging epidemiologic issues
- Professor, Epidemiology, Boston University School of Public Health
- Chief, Rheumatology, Medicine, Boston Medical Center
- Investigator, Framingham Heart Study
- Member, Arthritis & Autoimmune Diseases Research Center, Boston University
- Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
- Section Chief of Rheumatology, Rheumatology, Medicine, Boston University School of Medicine
- University of Toronto, MD
- Boston University School of Public Health, PhD
- McMaster University, BS
- Published on 3/25/2021
Macri EM, Neogi T, Jarraya M, Guermazi A, Roemer F, Lewis CE, Torner JC, Lynch JA, Tolstykh I, Jafarzadeh SR, Stefanik JJ. Can MRI-defined osteoarthritis features explain anterior knee pain in individuals with, or at risk for, knee osteoarthritis? The MOST Study. Arthritis Care Res (Hoboken). 2021 Mar 25. PMID: 33768706.
- Published on 3/23/2021
Chen AT, Bronsther CI, Stanley EE, Paltiel AD, Sullivan JK, Collins JE, Neogi T, Katz JN, Losina E. The Value of Total Knee Replacement in Patients With Knee Osteoarthritis and a Body Mass Index of 40 kg/m2 or Greater : A Cost-Effectiveness Analysis. Ann Intern Med. 2021 Mar 23. PMID: 33750190.
- Published on 3/20/2021
Costello KE, Felson DT, Neogi T, Segal NA, Lewis CE, Gross KD, Nevitt MC, Lewis CL, Kumar D. Ground reaction force patterns in knees with and without radiographic osteoarthritis and pain: descriptive analyses of a large cohort (the Multicenter Osteoarthritis Study). Osteoarthritis Cartilage. 2021 Mar 20. PMID: 33757856.
- Published on 3/1/2021
Berry KM, Neogi T, Baker JF, Collins JM, Waggoner JR, Hsiao CW, Johnston SS, LaValley MP, Stokes AC. Obesity Progression Between Young Adulthood and Midlife and Incident Arthritis: A Retrospective Cohort Study of US Adults. Arthritis Care Res (Hoboken). 2021 03; 73(3):318-327. PMID: 32374930.
- Published on 2/24/2021
Huizinga JL, Stanley EE, Sullivan JK, Song S, Hunter DJ, Paltiel AD, Neogi T, Edwards RR, Katz JN, Losina E. Societal Cost of Opioid Use in Symptomatic Knee Osteoarthritis Patients in the United States. Arthritis Care Res (Hoboken). 2021 Feb 24. PMID: 33629485.
- Published on 2/24/2021
Sinha P, Jafarzadeh SR, Assoumou SA, Bielick CG, Carpenter B, Garg S, Harleen S, Neogi T, Nishio MJ, Sagar M, Sharp V, Kissin EY. The Effect of IL-6 Inhibitors on Mortality Among Hospitalized COVID-19 Patients: A Multicenter Study. J Infect Dis. 2021 02 24; 223(4):581-588. PMID: 33216906.
- Published on 2/1/2021
Jagpal A, Rahn EJ, Mudano AS, Dalbeth N, Taylor W, Saag KG, Singh JA, Cavagna L, Uhlig T, Perez-Ruiz F, McCarthy G, Gerritsen M, Stamp L, Vazquez Mellado J, Lin C, Vargas-Santos AB, Louthrenoo W, Neogi T, Chen YH, Castelar-Pinheiro GDR, Gaffo A. Which factors predict discordance between a patient and physician on a gout flare? Rheumatology (Oxford). 2021 Feb 01; 60(2):773-779. PMID: 32793971.
- Published on 1/29/2021
Fraenkel L, Wei Z, Ramsey C, Wiedmeyer C, Michaud K, Neogi T, Nowell WB, Venkatachalam S, Broniatowski DA. OPEX: Development of a novel overall patient experience measure to facilitate interpretation of comparison effectiveness studies. PLoS One. 2021; 16(1):e0245598. PMID: 33513209.
- Published on 1/27/2021
Neogi T, Dalbeth N, Mikuls TR, Turner AS, FitzGerald JD. Reply. Arthritis Rheumatol. 2021 03; 73(3):544-545. PMID: 32936518.
- Published on 1/27/2021
Kim SC, Neogi T, Kim E, Lii J, Desai RJ. Trends in Utilization of Urate-Lowering Therapies Following the US Food and Drug Administration's Boxed Warning on Febuxostat. Arthritis Rheumatol. 2021 03; 73(3):542-543. PMID: 33029931.
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