Shinichiro Kurosawa, MD, PhD

Associate Professor, Pathology & Laboratory Medicine

617.414.7091
670 Albany St Biosquare III

Biography

Expertise includes: Internal Medicine; Hematology; Thrombosis and Hemostasis; Disseminated Intravascular Coagulation (DIC); Thrombotic Microangiopathy (TMA); Sepsis and septic shock; Infectious diseases; Protein C pathway; Cytokine, chemokines and biomarkers; Development of pre-clinical animal models of human diseases; Shiga-toxins; and Hemolytic Uremic Syndrome (HUS).

Other Positions

  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Education

  • Gunma University, MD
  • Gunma University, PhD

Classes Taught

  • GMSOH700

Publications

  • Published on 1/1/2021

    Hall G, Kurosawa S, Stearns-Kurosawa DJ. Infection of Immunocompetent Conventional Mice with Shiga Toxin-Producing E. coli: The DSS + STEC Model. Methods Mol Biol. 2021; 2291:353-364. PMID: 33704763.

    Read at: PubMed
  • Published on 4/17/2019

    Feng F, Thompson MP, Thomas BE, Duffy ER, Kim J, Kurosawa S, Tashjian JY, Wei Y, Andry C, Stearns-Kurosawa DJ. A computational solution to improve biomarker reproducibility during long-term projects. PLoS One. 2019; 14(4):e0209060. PMID: 30995241.

    Read at: PubMed
  • Published on 10/25/2018

    Hall G, Kurosawa S, Stearns-Kurosawa DJ. Dextran Sulfate Sodium Colitis Facilitates Colonization with Shiga Toxin-Producing Escherichia coli: a Novel Murine Model for the Study of Shiga Toxicosis. Infect Immun. 2018 11; 86(11). PMID: 30150257.

    Read at: PubMed
  • Published on 2/27/2018

    Kara V, Duan C, Gupta K, Kurosawa S, Stearns-Kurosawa DJ, Ekinci KL. Microfluidic detection of movements of Escherichia coli for rapid antibiotic susceptibility testing. Lab Chip. 2018 02 27; 18(5):743-753. PMID: 29387860.

    Read at: PubMed
  • Published on 9/19/2017

    Hall G, Kurosawa S, Stearns-Kurosawa DJ. Shiga Toxin Therapeutics: Beyond Neutralization. Toxins (Basel). 2017 Sep 19; 9(9). PMID: 28925976.

    Read at: PubMed
  • Published on 4/7/2015

    Mayer CL, Parello CS, Lee BC, Itagaki K, Kurosawa S, Stearns-Kurosawa DJ. Pro-Coagulant Endothelial Dysfunction Results from EHEC Shiga Toxins and Host Damage-Associated Molecular Patterns. Front Immunol. 2015; 6:155. PMID: 25904918.

    Read at: PubMed
  • Published on 1/20/2015

    Parello CS, Mayer CL, Lee BC, Motomochi A, Kurosawa S, Stearns-Kurosawa DJ. Shiga toxin 2-induced endoplasmic reticulum stress is minimized by activated protein C but does not correlate with lethal kidney injury. Toxins (Basel). 2015 Jan; 7(1):170-86. PMID: 25609181.

    Read at: PubMed
  • Published on 12/31/2014

    Kurosawa S, Stearns-Kurosawa DJ. Complement, thrombotic microangiopathy and disseminated intravascular coagulation. J Intensive Care. 2014; 2(1):65. PMID: 25705421.

    Read at: PubMed
  • Published on 7/1/2013

    Iskander KN, Osuchowski MF, Stearns-Kurosawa DJ, Kurosawa S, Stepien D, Valentine C, Remick DG. Sepsis: multiple abnormalities, heterogeneous responses, and evolving understanding. Physiol Rev. 2013 Jul; 93(3):1247-88. PMID: 23899564.

    Read at: PubMed
  • Published on 6/7/2013

    Coggeshall KM, Lupu F, Ballard J, Metcalf JP, James JA, Farris D, Kurosawa S. The sepsis model: an emerging hypothesis for the lethality of inhalation anthrax. J Cell Mol Med. 2013 Jul; 17(7):914-20. PMID: 23742651.

    Read at: PubMed

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