Shinichiro Kurosawa, MD, PhD

Associate Professor, Pathology & Laboratory Medicine

617.414.7091
670 Albany St Biosquare III

Biography

Expertise includes: Internal Medicine; Hematology; Thrombosis and Hemostasis; Disseminated Intravascular Coagulation (DIC); Thrombotic Microangiopathy (TMA); Sepsis and septic shock; Infectious diseases; Protein C pathway; Cytokine, chemokines and biomarkers; Development of pre-clinical animal models of human diseases; Shiga-toxins; and Hemolytic Uremic Syndrome (HUS).

Other Positions

  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences

Education

  • Gunma University, MD
  • Gunma University, PhD

Publications

  • Published on 8/27/2018

    Hall G, Kurosawa S, Stearns-Kurosawa D. Dextran sulfate sodium colitis facilitates colonization with Shiga-toxin producing E. coli: A novel murine model for the study of Shiga toxicosis. Infect Immun. 2018 Aug 27. PMID: 30150257.

    Read at: PubMed
  • Published on 2/27/2018

    Kara V, Duan C, Gupta K, Kurosawa S, Stearns-Kurosawa DJ, Ekinci KL. Microfluidic detection of movements of Escherichia coli for rapid antibiotic susceptibility testing. Lab Chip. 2018 02 27; 18(5):743-753. PMID: 29387860.

    Read at: PubMed
  • Published on 9/19/2017

    Hall G, Kurosawa S, Stearns-Kurosawa DJ. Shiga Toxin Therapeutics: Beyond Neutralization. Toxins (Basel). 2017 Sep 19; 9(9). PMID: 28925976.

    Read at: PubMed
  • Published on 4/7/2015

    Mayer CL, Parello CS, Lee BC, Itagaki K, Kurosawa S, Stearns-Kurosawa DJ. Pro-Coagulant Endothelial Dysfunction Results from EHEC Shiga Toxins and Host Damage-Associated Molecular Patterns. Front Immunol. 2015; 6:155. PMID: 25904918.

    Read at: PubMed
  • Published on 1/20/2015

    Parello CS, Mayer CL, Lee BC, Motomochi A, Kurosawa S, Stearns-Kurosawa DJ. Shiga toxin 2-induced endoplasmic reticulum stress is minimized by activated protein C but does not correlate with lethal kidney injury. Toxins (Basel). 2015 Jan; 7(1):170-86. PMID: 25609181.

    Read at: PubMed
  • Published on 12/31/2014

    Kurosawa S, Stearns-Kurosawa DJ. Complement, thrombotic microangiopathy and disseminated intravascular coagulation. J Intensive Care. 2014; 2(1):65. PMID: 25705421.

    Read at: PubMed
  • Published on 7/1/2013

    Iskander KN, Osuchowski MF, Stearns-Kurosawa DJ, Kurosawa S, Stepien D, Valentine C, Remick DG. Sepsis: multiple abnormalities, heterogeneous responses, and evolving understanding. Physiol Rev. 2013 Jul; 93(3):1247-88. PMID: 23899564.

    Read at: PubMed
  • Published on 6/7/2013

    Coggeshall KM, Lupu F, Ballard J, Metcalf JP, James JA, Farris D, Kurosawa S. The sepsis model: an emerging hypothesis for the lethality of inhalation anthrax. J Cell Mol Med. 2013 Jul; 17(7):914-20. PMID: 23742651.

    Read at: PubMed
  • Published on 6/3/2013

    Lee BC, Mayer CL, Leibowitz CS, Stearns-Kurosawa DJ, Kurosawa S. Quiescent complement in nonhuman primates during E coli Shiga toxin-induced hemolytic uremic syndrome and thrombotic microangiopathy. Blood. 2013 Aug 1; 122(5):803-6. PMID: 23733336.

    Read at: PubMed
  • Published on 2/10/2013

    Stearns-Kurosawa DJ, Oh SY, Cherla RP, Lee MS, Tesh VL, Papin J, Henderson J, Kurosawa S. Distinct renal pathology and a chemotactic phenotype after enterohemorrhagic Escherichia coli shiga toxins in non-human primate models of hemolytic uremic syndrome. Am J Pathol. 2013 Apr; 182(4):1227-38. PMID: 23402998.

    Read at: PubMed

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