S. Reza Jafarzadeh, DVM, MPVM, PhD

Assistant Professor, Medicine

S. Reza Jafarzadeh
617.358.9665
650 Albany Street, Suite X200

Biography

I am interested in the application of causal inference methods in observational studies, especially in the setting of longitudinal data, where time-varying exposures, time-dependent confounding, and selection bias are often present. In particular, I am interested in the application of the variety of modern analytical techniques for estimating causal effects as well as the concepts such as direct and indirect effect decomposition (causal mediation analysis), causal interactions and sufficient causes, and causal interference and spill-over effects. These analytical techniques can be applied to broad areas of health sciences research, but I am particularly interested in the application of causal inference for comparative effectiveness research and implementation science. The methods are very useful for the development and assessment of strategies to improve population health using non-experimental data.

I am also interested in the application of Bayesian methods for evaluation of diagnostic tests and prevalence estimation in the absence of a perfect reference standard. These methods have broad applications in diagnosis and screening, and can be used to estimate true prevalence using imperfect tests.

Other Positions

  • Member, Arthritis & Autoimmune Diseases Research Center, Boston University

Education

  • University of Tehran, DVM
  • University of California, Davis, MPVM
  • University of California, Davis, PhD

Publications

  • Published on 12/23/2022

    Bacon KL, Felson DT, Jafarzadeh SR, Kolachalama VB, Hausdorff JM, Gazit E, Segal NA, Lewis CE, Nevitt MC, Kumar D. Relation of gait measures with mild unilateral knee pain during walking using machine learning. Sci Rep. 2022 Dec 23; 12(1):22200. PMID: 36564397.

    Read at: PubMed
  • Published on 10/15/2022

    Riddle DL, Reza Jafarzadeh S. Effects of psychological distress on the general health to self-reported pain and function outcome relationship in knee arthroplasty: A causal mediation study. Osteoarthr Cartil Open. 2022 Dec; 4(4):100315. PMID: 36474788.

    Read at: PubMed
  • Published on 9/28/2022

    Rose MJ, LaValley MP, Jafarzadeh SR, Costello KE, Shah N, Lee S, Borrelli B, Messier SP, Neogi T, Kumar D. Impact of COVID-19 Pandemic on Physical Activity, Pain, Mood, and Sleep in Adults with Knee Osteoarthritis. J Meas Phys Behav. 2022 Dec; 5(4):294-298. PMID: 36779003.

    Read at: PubMed
  • Published on 9/2/2022

    Jafarzadeh SR, Neogi T. Causal inference from observational data and target trial emulation. Osteoarthritis Cartilage. 2022 Nov; 30(11):1415-1417. PMID: 36063988.

    Read at: PubMed
  • Published on 9/1/2022

    Jafarzadeh SR, Neogi T, White DK, Felson DT. The Relationship of Pain Reduction With Prevention of Knee Replacement Under Dynamic Intervention Strategies. Arthritis Rheumatol. 2022 Oct; 74(10):1668-1675. PMID: 35726122.

    Read at: PubMed
  • Published on 6/28/2022

    Gl√łersen M, Neogi T, Jafarzadeh SR, Sexton J, Haugen IK. Reply. Arthritis Rheumatol. 2022 Aug; 74(8):1454-1455. PMID: 35358373.

    Read at: PubMed
  • Published on 6/11/2022

    Carlesso LC, Jafarzadeh SR, Stokes A, Felson DT, Wang N, Frey-Law L, Lewis CE, Nevitt M, Neogi T. Depressive symptoms and multi-joint pain partially mediate the relationship between obesity and opioid use in people with knee osteoarthritis. Osteoarthritis Cartilage. 2022 Sep; 30(9):1263-1269. PMID: 35700904.

    Read at: PubMed
  • Published on 6/8/2022

    Macri EM, Neogi T, Jarraya M, Guermazi A, Roemer F, Lewis CE, Torner JC, Lynch JA, Tolstykh I, Jafarzadeh SR, Stefanik JJ. Magnetic Resonance Imaging-Defined Osteoarthritis Features and Anterior Knee Pain in Individuals With, or at Risk for, Knee Osteoarthritis: A Multicenter Study on Osteoarthritis. Arthritis Care Res (Hoboken). 2022 Sep; 74(9):1533-1540. PMID: 33768706.

    Read at: PubMed
  • Published on 3/23/2022

    Gl√łersen M, Steen Pettersen P, Neogi T, Jafarzadeh SR, Vistnes M, Thudium CS, Bay-Jensen AC, Sexton J, Kvien TK, Hammer HB, Haugen IK. Associations of Body Mass Index With Pain and the Mediating Role of Inflammatory Biomarkers in People With Hand Osteoarthritis. Arthritis Rheumatol. 2022 May; 74(5):810-817. PMID: 35137553.

    Read at: PubMed
  • Published on 12/1/2021

    Liew JW, Jafarzadeh SR, Dubreuil M, Heckbert SR, Mooney SJ, Brown MA, Ishimori ML, Reveille JD, Ward MM, Weisman MH, Gensler LS. The Association of Tumor Necrosis Factor Inhibitor Use With Incident Hypertension in Ankylosing Spondylitis: Data From the PSOAS Cohort. J Rheumatol. 2022 03; 49(3):274-280. PMID: 34853088.

    Read at: PubMed

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