S. Reza Jafarzadeh, DVM, MPVM, PhD
Associate Professor, Medicine
Biography
I am interested in the application of causal inference methods in observational studies, especially in the setting of longitudinal data, where time-varying exposures, time-dependent confounding, and selection bias are often present. In particular, I am interested in the application of the variety of modern analytical techniques for estimating causal effects as well as the concepts such as direct and indirect effect decomposition (causal mediation analysis), causal interactions and sufficient causes, and causal interference and spill-over effects. These analytical techniques can be applied to broad areas of health sciences research, but I am particularly interested in the application of causal inference for comparative effectiveness research and implementation science. The methods are very useful for the development and assessment of strategies to improve population health using non-experimental data.
I am also interested in the application of Bayesian methods for evaluation of diagnostic tests and prevalence estimation in the absence of a perfect reference standard. These methods have broad applications in diagnosis and screening, and can be used to estimate true prevalence using imperfect tests.
Other Positions
- Member, Arthritis & Autoimmune Diseases Research Center, Boston University
Education
- University of Tehran, DVM
- University of California, Davis, MPVM
- University of California, Davis, PhD
Publications
- Published on 4/1/2025
Ferrandiz-Espadin R, Rabasa G, Gasman S, McGinley B, Stovall R, Jafarzadeh SR, Liew JW, Dubreuil M. Disparities in Time to Diagnosis of Radiographic Axial Spondyloarthritis. J Rheumatol. 2025 Apr 01; 52(4):344-351. PMID: 39486857.
Read at: PubMed - Published on 3/18/2025
Lee S, Neogi T, Senderling BM, Jafarzadeh SR, Gheller M, Tuttle PG, Demanuele C, Viktrup L, Wacnik P, Kumar D. Association of pain during exercise with exercise-induced hypoalgesia in people with knee osteoarthritis. Arthritis Care Res (Hoboken). 2025 Mar 18. PMID: 40099368.
Read at: PubMed - Published on 12/16/2024
Driscoll D, George N, Peloquin C, Jafarzadeh SR, Liew JW, Dubreuil M. Association of Therapies for Axial Spondyloarthritis on the Risk of Hip and Spine Fractures. Arthritis Rheumatol. 2024 Dec 16. PMID: 39679763.
Read at: PubMed - Published on 7/1/2024
Myers LC, Bosch NA, Soltesz L, Daly KA, Campbell CI, Schwager E, Salvati E, Stevens JP, Wunsch H, Rucci JM, Jafarzadeh SR, Liu VX, Walkey AJ. Opioid Administration Practice Patterns in Patients With Acute Respiratory Failure Who Undergo Invasive Mechanical Ventilation. Crit Care Explor. 2024 Jul 01; 6(7):e1123. PMID: 39018285.
Read at: PubMed - Published on 6/3/2024
Myers LC, Soltesz L, Bosch N, Daly KA, Devis Y, Rucci J, Stevens J, Wunsch H, Jafarzadeh SR, Campbell CI, Liu VX, Walkey AJ. Intravenous Opioid Administration During Mechanical Ventilation and Use After Hospital Discharge. JAMA Netw Open. 2024 Jun 03; 7(6):e2417292. PMID: 38874921.
Read at: PubMed - Published on 4/17/2024
Bacon KL, Felson DT, Jafarzadeh SR, Kolachalama VB, Hausdorff JM, Gazit E, Stefanik JJ, Corrigan P, Segal NA, Lewis CE, Nevitt MC, Kumar D. Gait Alterations and Association With Worsening Knee Pain and Physical Function: A Machine Learning Approach With Wearable Sensors in the Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). 2024 Jul; 76(7):984-992. PMID: 38523250.
Read at: PubMed - Published on 3/22/2024
Bosch NA, Law AC, Shi Z, Jafarzadeh SR, Walkey AJ. A novel measure to summarize blood transfusion practice during critical illness. Transfusion. 2024 May; 64(5):784-788. PMID: 38515390.
Read at: PubMed - Published on 1/1/2024
Bosch NA, Myers LC, Jafarzadeh SR, Wunsch H, Stevens JP, Liu VX, Walkey AJ. Temporal Trends in Use of Opioids for Patients with Acute Respiratory Failure following "Analgesia-First" Sedation Guidelines. Ann Am Thorac Soc. 2024 Jan; 21(1):179-183. PMID: 37847821.
Read at: PubMed - Published on 12/28/2023
Aoyagi K, Jafarzadeh SR, Carlesso L, Frey Law L, Lewis CE, Nevitt M, Neogi T. Mediating Effect of Pain Sensitization on the Paradoxical Relation of Taking Opioids to Pain Severity in Knee Osteoarthritis: The Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). 2024 Mar; 76(3):403-408. PMID: 37750238.
Read at: PubMed - Published on 10/15/2023
Liew JW, Jarraya M, Guermazi A, Lynch J, Wang N, Rabasa G, Jafarzadeh SR, Nevitt M, Torner J, Lewis CE, Felson DT, Neogi T. Relation of Intra-Articular Mineralization to Knee Pain in Knee Osteoarthritis: A Longitudinal Analysis in the MOST Study. Arthritis Rheumatol. 2023 Dec; 75(12):2161-2168. PMID: 37410792.
Read at: PubMed
View 53 more publications: View full profile at BUMC