Robert A. Davey, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Robert Davey, PhD is a currently a Professor of Microbiology at the Chobanian and Avedisian School of Medicine. Dr. Davey received his doctorate in Microbiology and Immunology at the University of Adelaide in Australia. He continued his training as a Postdoctoral Fellow at the Howard Hughes Medical Institute and then at the Division of Hematology, both with Dr. James Cunningham at Brigham and Women's Hospital and Harvard Medical School.

Dr. Davey's first academic appointment was as an Instructor in Medicine at Harvard. He then held an Assistant Professor position which he got promoted to Adjunct Associate Professor at the Department of Microbiology and Immunology at the University of Texas Medical Branch.

Dr. Davey was also a Ewing Halsell Scholar and Scientist at the Department of Virology and Immunology at the Texas Biomedical Research Institute. As a Scientist at the Texas Biomedical Research Institute, Dr. Davey's work was focused on identification of cellular factors important for establishing infection by filovirus and bunyaviruses. His work has culminated in a deeper understanding of the entry and cell signaling pathways that are used by these viruses to penetrate the cell membrane and establish infection. His work with Ebolavirus has been published in the high-impact journals PLoS Pathogens, PNAS and a new article on host factor dependence in Science that was featured on the cover page. Dr. Davey’s group works collaboratively with a number of groups providing sophisticated molecular biology and cell biology techniques for the study of pathogenic viruses including Ebolavirus for which the lab mainly works. He has developed high throughput screening techniques for Ebolavirus. He also performs contract work testing drugs and compounds for ebolavirus infection inhibition. His team is well trained in ABSL4 procedures and have been working with Ebolavirus since 2006.

From 2015-2017, Dr. Davey held the role of Interim Chair in the Department of Virology and Immunology at the Texas Biomedical Research Institute. He is also Director of ABSL4 at the Texas Biomedical Research Institute.

Publications

  • Published 9/22/2025

    Uwase G, Luthra P, Vogel OA, Batra J, La Rosa BA, Sheehan KCF, Khatavkar O, Payton JE, Davey RA, Krogan NJ, Basler CF, Leung DW, Amarasinghe GK. Ebola virus VP35 NNLNS motif modulates viral RNA synthesis and MIB2-mediated signaling. Proc Natl Acad Sci U S A. 2025 Sep 30; 122(39):e2411961122. PMID: 40982696.

    Read at: PubMed

  • Published 9/19/2025

    Hanke S, Giannikopoulos D, Neumayer B, Vedenkannas T, Davey R, Mpaltadoros L, Guthrie B, Jackson R, Lagerwaard B, Zuidgeest M. Operationalizing Decentralized Clinical Trials: Technology Insights from the Trials@Home RADIAL Proof-of-Concept Trial. Clin Pharmacol Ther. 2025 Sep 19. PMID: 40970561.

    Read at: PubMed

  • Published 7/27/2025

    Uwase G, Luthra P, Vogel OA, Batra J, La Rosa BA, Sheehan KCF, Khatavkar O, Payton JE, Davey RA, Krogan NJ, Basler CF, Leung DW, Amarasinghe GK. Ebola virus VP35 NNLNS motif modulates viral RNA synthesis and MIB2-mediated signaling. bioRxiv. 2025 Jul 27. PMID: 40777377.

    Read at: PubMed

  • Published 7/24/2025

    Carlson RJ, Patten JJ, Stefanakis G, Soong BY, Radhakrishnan A, Singh A, Thakur N, Sheehan KCF, Amarasinghe GK, Hacohen N, Basler CF, Leung DW, Uhler C, Davey RA, Blainey PC. Single-cell image-based screens identify host regulators of Ebola virus infection dynamics. Nat Microbiol. 2025 Aug; 10(8):1989-2002. PMID: 40707832.

    Read at: PubMed

  • Published 7/2/2025

    Singh K, Patten JJ, Dimet-Wiley A, Davey RA, Watowich SJ, Chandra A, Leverett J. Unlocking the potential of phytochemicals in inhibiting SARS-CoV-2 MPro protein - an in silico and cell-based approach. Sci Rep. 2025 Jul 02; 15(1):22840. PMID: 40596019.

    Read at: PubMed

Other Positions

  • Interim Director, National Emerging Infectious Disease Lab
    Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University Chobanian & Avedisian School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences