Raphael A. Zoeller, PhD

Associate Professor, Physiology & Biophysics

Raphael Zoeller
700 Albany St Ctr for Adv Biomed Res


My expertise is in the area of lipid biosynthesis and metabolism and how they relate to human disease. My laboratory uses molecular biology, lipid chemistry & analysis, protein chemistry and forward genetics (mutant isolation).

Other Positions

  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
  • Research Assistant Professor, Biomedical Genetics, Medicine, Boston University School of Medicine


  • Texas A&M University, PhD
  • University of Maine, BS

Classes Taught

  • FC701
  • MD514 A1
  • MS 146 M2
  • PH731
  • PS 702


  • Published on 3/14/2018

    Werner ER, Keller MA, Sailer S, Seppi D, Golderer G, Werner-Felmayer G, Zoeller RA, Watschinger K. A novel assay for the introduction of the vinyl ether double bond into plasmalogens using pyrene-labeled substrates. J Lipid Res. 2018 May; 59(5):901-909. PMID: 29540573.

    Read at: PubMed
  • Published on 5/25/2012

    Nakahara K, Ohkuni A, Kitamura T, Abe K, Naganuma T, Ohno Y, Zoeller RA, Kihara A. The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway. Mol Cell. 2012 May 25; 46(4):461-71. PMID: 22633490.

    Read at: PubMed
  • Published on 4/6/2012

    Krawczyk SA, Haller JF, Ferrante T, Zoeller RA, Corkey BE. Reactive oxygen species facilitate translocation of hormone sensitive lipase to the lipid droplet during lipolysis in human differentiated adipocytes. PLoS One. 2012; 7(4):e34904. PMID: 22493722.

    Read at: PubMed
  • Published on 7/21/2011

    Haller JF, Krawczyk SA, Gostilovitch L, Corkey BE, Zoeller RA. Glucose-6-phosphate isomerase deficiency results in mTOR activation, failed translocation of lipin 1a to the nucleus and hypersensitivity to glucose: Implications for the inherited glycolytic disease. Biochim Biophys Acta. 2011 Nov; 1812(11):1393-402. PMID: 21787864.

    Read at: PubMed
  • Published on 12/17/2009

    Anbukumar DS, Shornick LP, Albert CJ, Steward MM, Zoeller RA, Neumann WL, Ford DA. Chlorinated lipid species in activated human neutrophils: lipid metabolites of 2-chlorohexadecanal. J Lipid Res. 2010 May; 51(5):1085-92. PMID: 20019386.

    Read at: PubMed
  • Published on 11/10/2009

    Haller JF, Smith C, Liu D, Zheng H, Tornheim K, Han GS, Carman GM, Zoeller RA. Isolation of novel animal cell lines defective in glycerolipid biosynthesis reveals mutations in glucose-6-phosphate isomerase. J Biol Chem. 2010 Jan 8; 285(2):866-77. PMID: 19903819.

    Read at: PubMed
  • Published on 2/20/2008

    Gaposchkin DP, Farber HW, Zoeller RA. On the importance of plasmalogen status in stimulated arachidonic acid release in the macrophage cell line RAW 264.7. Biochim Biophys Acta. 2008 Apr; 1781(4):213-9. PMID: 18328831.

    Read at: PubMed
  • Published on 12/20/2005

    Zheng H, Duclos RI, Smith CC, Farber HW, Zoeller RA. Synthesis and biological properties of the fluorescent ether lipid precursor 1-O-[9'-(1'-pyrenyl)]nonyl-sn-glycerol. J Lipid Res. 2006 Mar; 47(3):633-42. PMID: 16369049.

    Read at: PubMed
  • Published on 2/1/2005

    Liu D, Nagan N, Just WW, Rodemer C, Thai TP, Zoeller RA. Role of dihydroxyacetonephosphate acyltransferase in the biosynthesis of plasmalogens and nonether glycerolipids. J Lipid Res. 2005 Apr; 46(4):727-35. PMID: 15687349.

    Read at: PubMed
  • Published on 1/1/2003

    Munn NJ, Arnio E, Liu D, Zoeller RA, Liscum L. Deficiency in ethanolamine plasmalogen leads to altered cholesterol transport. J Lipid Res. 2003 Jan; 44(1):182-92. PMID: 12518037.

    Read at: PubMed

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