Pietro Cottone, PhD

Associate Professor, Pharmacology & Experimental Therapeutics

Pietro Cottone
72 E. Concord St Housman (R)


Dr. Cottone is co-director of the Laboratory of Addictive Disorders. Dr. Cottone’s research interests focus on the neurobiological substrates of motivated behaviors including feeding and addiction. The major goal of Dr. Cottone’s research is identifying the biological bases of and potential treatments for eating disorders and obesity. Current studies concern the role of stress in compulsive eating and palatable food dependence. Areas of focused research include the investigation of the neurobiological bases of stress-related disorders such as anxiety and depression. Dr. Cottone’s studies are carried out on environmental and genetic animal models, using behavioral, biochemical, and molecular approaches.

Dr. Cottone co-directs a graduate course in neuropsychopharmacology offered for the first time in Fall 2010 which examines the interaction between behavior and classes of drugs that affect the central nervous system.

Other Positions

  • Associate Professor, Psychiatry, Boston University School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences


  • University of Rome, PhD
  • University of Palermo, PharmD
  • University of Palermo, MS
  • University of Palermo, BS

Classes Taught

  • GMSMS710
  • GMSPM702
  • GMSPM801
  • GMSPM810
  • GMSPM820
  • GMSPM820
  • GMSPM820
  • GMSPM932
  • MEDMS220
  • SMDMD530


  • Published on 9/10/2021

    Valentina S, Blasio A, Ferragud A, Quadir SG, Iyer MR, Rice KC, Cottone P. Characterization of a differential reinforcement of low rates of responding task in non-deprived male and female rats: Role of Sigma-1 receptors. Neuropharmacology. 2021 12 01; 200:108786. PMID: 34516984.

    Read at: PubMed
  • Published on 7/5/2021

    Quadir SG, Tanino SM, Sami YN, Minnig MA, Iyer MR, Rice KC, Cottone P, Sabino V. Antagonism of Sigma-1 receptor blocks heavy alcohol drinking and associated hyperalgesia in male mice. Alcohol Clin Exp Res. 2021 07; 45(7):1398-1407. PMID: 34060104.

    Read at: PubMed
  • Published on 11/20/2020

    Quadir SG, Tanino SM, Rohl CD, Sahn JJ, Yao EJ, Cruz LDR, Cottone P, Martin SF, Sabino V. The Sigma-2 receptor / transmembrane protein 97 (s2R/TMEM97) modulator JVW-1034 reduces heavy alcohol drinking and associated pain states in male mice. Neuropharmacology. 2021 02 15; 184:108409. PMID: 33221481.

    Read at: PubMed
  • Published on 11/16/2020

    Ferragud A, Velazquez-Sanchez C, Minnig MA, Sabino V, Cottone P. Pituitary adenylate cyclase-activating polypeptide (PACAP) modulates dependence-induced alcohol drinking and anxiety-like behavior in male rats. Neuropsychopharmacology. 2021 02; 46(3):509-518. PMID: 33191400.

    Read at: PubMed
  • Published on 5/30/2020

    Lee HS, Giunti E, Sabino V, Cottone P. Consummatory, Feeding Microstructural, and Metabolic Effects Induced by Limiting Access to Either a High-Sucrose or a High-Fat Diet. Nutrients. 2020 May 30; 12(6). PMID: 32486207.

    Read at: PubMed
  • Published on 5/28/2020

    Hicks C, Sabino V, Cottone P. The Alpha-1 Adrenergic Receptor Antagonist Prazosin Reduces Binge-Like Eating in Rats. Nutrients. 2020 May 28; 12(6). PMID: 32481494.

    Read at: PubMed
  • Published on 5/23/2020

    Ferragud A, Velázquez-Sánchez C, Abdullatif AA, Sabino V, Cottone P. Withdrawal from Extended, Intermittent Access to A Highly Palatable Diet Impairs Hippocampal Memory Function and Neurogenesis: Effects of Memantine. Nutrients. 2020 May 23; 12(5). PMID: 32456193.

    Read at: PubMed
  • Published on 4/21/2020

    Quadir SG, Rohl CD, Zeabi A, Moore CF, Cottone P, Sabino V. Effect of different standard rodent diets on ethanol intake and associated allodynia in male mice. Alcohol. 2020 09; 87:17-23. PMID: 32330590.

    Read at: PubMed
  • Published on 3/20/2020

    Valenza M, Blasio A, DiLeo A, Cottone P, Sabino V. Sigma receptor-induced heavy drinking in rats: Modulation by the opioid receptor system. Pharmacol Biochem Behav. 2020 05; 192:172914. PMID: 32205151.

    Read at: PubMed
  • Published on 10/17/2019

    Moore CF, Leonard MZ, Micovic NM, Miczek KA, Sabino V, Cottone P. Reward sensitivity deficits in a rat model of compulsive eating behavior. Neuropsychopharmacology. 2020 03; 45(4):589-596. PMID: 31622973.

    Read at: PubMed

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