Dr. Cottone is co-director of the Laboratory of Addictive Disorders. Dr. Cottone’s research interests focus on the neurobiological substrates of motivated behaviors including feeding and addiction. The major goal of Dr. Cottone’s research is identifying the biological bases of and potential treatments for eating disorders and obesity. Current studies concern the role of stress in compulsive eating and palatable food dependence. Areas of focused research include the investigation of the neurobiological bases of stress-related disorders such as anxiety and depression. Dr. Cottone’s studies are carried out on environmental and genetic animal models, using behavioral, biochemical, and molecular approaches.
Dr. Cottone co-directs a graduate course in neuropsychopharmacology offered for the first time in Fall 2010 which examines the interaction between behavior and classes of drugs that affect the central nervous system.
- Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences
- Associate Professor, Psychiatry, Boston University School of Medicine
- University of Rome, PhD
- University of Palermo, MS
- University of Palermo, BS
- University of Palermo, PharmD
- Published on 11/20/2017
Apicco DJ, Ash PEA, Maziuk B, LeBlang C, Medalla M, Al Abdullatif A, Ferragud A, Botelho E, Ballance HI, Dhawan U, Boudeau S, Cruz AL, Kashy D, Wong A, Goldberg LR, Yazdani N, Zhang C, Ung CY, Tripodis Y, Kanaan NM, Ikezu T, Cottone P, Leszyk J, Li H, Luebke J, Bryant CD, Wolozin B. Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo. Nat Neurosci. 2018 Jan; 21(1):72-80. PMID: 29273772.
- Published on 10/31/2017
Moore CF, Schlain GS, Mancino S, Sabino V, Cottone P. A behavioral and pharmacological characterization of palatable diet alternation in mice. Pharmacol Biochem Behav. 2017 Dec; 163:1-8. PMID: 29097161.
- Published on 8/24/2017
Moore CF, Sabino V, Koob GF, Cottone P. Neuroscience of Compulsive Eating Behavior. Front Neurosci. 2017; 11:469. PMID: 28883784.
- Published on 1/1/2017
Sabino V, Hicks C, Cottone P. Sigma Receptors and Substance Use Disorders. Adv Exp Med Biol. 2017; 964:177-199. PMID: 28315272.
- Published on 1/1/2017
Sabino V, Cottone P. Sigma Receptors and Alcohol Use Disorders. Handb Exp Pharmacol. 2017; 244:219-236. PMID: 28039543.
- Published on 12/6/2016
Moore CF, Sabino V, Koob GF, Cottone P. Pathological Overeating: Emerging Evidence for a Compulsivity Construct. Neuropsychopharmacology. 2017 Jun; 42(7):1375-1389. PMID: 27922596.
- Published on 10/25/2016
Kirkpatrick SL, Goldberg LR, Yazdani N, Babbs RK, Wu J, Reed ER, Jenkins DF, Bolgioni AF, Landaverde KI, Luttik KP, Mitchell KS, Kumar V, Johnson WE, Mulligan MK, Cottone P, Bryant CD. Cytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating. Biol Psychiatry. 2017 May 01; 81(9):757-769. PMID: 27914629.
- Published on 10/6/2016
Ferragud A, Howell AD, Moore CF, Ta TL, Hoener MC, Sabino V, Cottone P. The Trace Amine-Associated Receptor 1 Agonist RO5256390 Blocks Compulsive, Binge-like Eating in Rats. Neuropsychopharmacology. 2017 Jun; 42(7):1458-1470. PMID: 27711047.
- Published on 7/4/2016
Iemolo A, Seiglie M, Blasio A, Cottone P, Sabino V. Pituitary adenylate cyclase-activating polypeptide (PACAP) in the central nucleus of the amygdala induces anxiety via melanocortin receptors. Psychopharmacology (Berl). 2016 Sep; 233(17):3269-77. PMID: 27376948.
- Published on 10/26/2015
Giuliano C, Cottone P. The role of the opioid system in binge eating disorder. CNS Spectr. 2015 Dec; 20(6):537-45. PMID: 26499083.
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