Paola Massari, PhD

Adjunct Research Associate Professor, Medicine

Paola Massari
617.414.4807
650 Albany St Evans Biomed Research Ctr

Biography

I am a PhD scientist with extensive expertise in research, operations and project management in academic research and pharmaceutical industry. I have 15+ years of experience in basic and translational research in innate immunity and inflammation, bacterial pathogenesis and host response, cell biology, protein biochemistry and structure, human and veterinary vaccine design and evaluation established in both academic and industrial settings.

My research areas focus on bacteria interplay with host cells and on the mechanisms of innate immunity mediated by bacterial products. Areas of strong interest include TLR signaling and vaccine development, characterization of protein structure/functions and interactions with host cell receptors in the context of cellular and molecular immunity.

I am a strong communicator of complex scientific information to diverse audiences with excellent scientific writing/editing skills and strong experience as scientific peer reviewer. Proven ability in cost analysis and grant management. My core administrative competencies include: Strategic Vision/Planning – Project Management – Efficiency Improvement – Problem Solving – Logic/Scientific Thinking – Lab Management – Best Practices, SOP, Protocols

Other Positions

  • Boston Medical Center

Education

  • Università degli Studi di Napoli Federico II, PhD
  • Università degli Studi di Napoli Federico II, MSc
  • Università degli Studi di Napoli Federico II, BS

Publications

  • Published on 6/27/2018

    Nudel K, McClure R, Moreau M, Briars E, Abrams AJ, Tjaden B, Su XH, Trees D, Rice PA, Massari P, Genco CA. Transcriptome Analysis of Neisseria gonorrhoeae during Natural Infection Reveals Differential Expression of Antibiotic Resistance Determinants between Men and Women. mSphere. 2018 08 29; 3(3). PMID: 29950382.

    Read at: PubMed
  • Published on 12/25/2017

    Madico G, Gursky O, Fairman J, Massari P. Structural and Immunological Characterization of Novel Recombinant MOMP-Based Chlamydial Antigens. Vaccines (Basel). 2017 Dec 25; 6(1). PMID: 29295593.

    Read at: PubMed
  • Published on 7/31/2017

    Moreau MR, Massari P, Genco CA. The ironclad truth: how in vivo transcriptomics and in vitro mechanistic studies shape our understanding of Neisseria gonorrhoeae gene regulation during mucosal infection. Pathog Dis. 2017 Jul 31; 75(5). PMID: 28520925.

    Read at: PubMed
  • Published on 7/1/2016

    Toussi DN, Wetzler LM, Liu X, Massari P. Neisseriae internalization by epithelial cells is enhanced by TLR2 stimulation. Microbes Infect. 2016 Oct; 18(10):627-638. PMID: 27373686.

    Read at: PubMed
  • Published on 5/9/2016

    Stefanelli P, Neri A, Tanabe M, Fazio C, Massari P. Typing and surface charges of the variable loop regions of PorB from Neisseria meningitidis. IUBMB Life. 2016 Jun; 68(6):488-95. PMID: 27156582.

    Read at: PubMed
  • Published on 8/5/2015

    McClure R, Nudel K, Massari P, Tjaden B, Su X, Rice PA, Genco CA. The Gonococcal Transcriptome during Infection of the Lower Genital Tract in Women. PLoS One. 2015; 10(8):e0133982. PMID: 26244506.

    Read at: PubMed
  • Published on 8/1/2015

    Massari P, Gunawardana J, Liu X, Wetzler LM. Correction for Massari et al., meningococcal porin PorB prevents cellular apoptosis in a Toll-like receptor 2- and NF-?B-independent manner. Infect Immun. 2015 Aug; 83(8):3339. PMID: 26157088.

    Read at: PubMed
  • Published on 6/15/2015

    Nudel K, Massari P, Genco CA. Neisseria gonorrhoeae Modulates Cell Death in Human Endocervical Epithelial Cells through Export of Exosome-Associated cIAP2. Infect Immun. 2015 Sep; 83(9):3410-7. PMID: 26077759.

    Read at: PubMed
  • Published on 1/10/2015

    Kattner C, Pfennig S, Massari P, Tanabe M. One-step purification and porin transport activity of the major outer membrane proteins P2 from Haemophilus influenzae, FomA from Fusobacterium nucleatum and PorB from Neisseria meningitidis. Appl Biochem Biotechnol. 2015 Mar; 175(6):2907-15. PMID: 25575589.

    Read at: PubMed
  • Published on 8/12/2014

    McClure R, Massari P. TLR-Dependent Human Mucosal Epithelial Cell Responses to Microbial Pathogens. Front Immunol. 2014; 5:386. PMID: 25161655.

    Read at: PubMed

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