My area of expertise is studying disease mechanisms in vascular biology. My recent research has focused on the effect of obesity and inflammation on vascular dysfunction. I have received two R01 grants to support this line of investigation and have additionally received a 5-year PPG project grant with Dr. Ken Walsh. I also have extensive expertise in echocardigraphy and currently collaborate with several investigators in the Department of Medicine.
- Active Staff Privileges, Medicine, Boston Medical Center
- Tufts University School of Medicine, MD
- Brandeis University, BA
- Published on 6/7/2019
Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K. Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction. Circulation. 2019 Aug 06; 140(6):487-499. PMID: 31170826.
- Published on 6/1/2019
Karki S, Farb MG, Sharma VM, Jash S, Zizza EJ, Hess DT, Carmine B, Carter CO, Pernar LI, Apovian CM, Puri V, Gokce N. Fat-Specific Protein 27 Regulation of Vascular Function in Human Obesity. J Am Heart Assoc. 2019 Jun 04; 8(11):e011431. PMID: 31433737.
- Published on 4/2/2019
Gopal DM, Ayalon N, Wang YC, Siwik D, Sverdlov A, Donohue C, Perez A, Downing J, Apovian C, Silva V, Panagia M, Kolachalama V, Ho JE, Liang CS, Gokce N, Colucci WS. Galectin-3 Is Associated With Stage B Metabolic Heart Disease and Pulmonary Hypertension in Young Obese Patients. J Am Heart Assoc. 2019 Apr 02; 8(7):e011100. PMID: 30929550.
- Published on 12/21/2018
Ngo DTM, Sverdlov AL, Karki S, Macartney-Coxson D, Stubbs RS, Farb MG, Carmine B, Hess DT, Colucci WS, Gokce N. Oxidative modifications of mitochondrial complex II are associated with insulin resistance of visceral fat in obesity. Am J Physiol Endocrinol Metab. 2019 02 01; 316(2):E168-E177. PMID: 30576243.
- Published on 12/11/2017
Zuriaga MA, Fuster JJ, Farb MG, MacLauchlan S, Bretón-Romero R, Karki S, Hess DT, Apovian CM, Hamburg NM, Gokce N, Walsh K. Activation of non-canonical WNT signaling in human visceral adipose tissue contributes to local and systemic inflammation. Sci Rep. 2017 12 11; 7(1):17326. PMID: 29229927.
- Published on 9/29/2017
Farb MG, Park SY, Karki S, Gokce N. Assessment of Human Adipose Tissue Microvascular Function Using Videomicroscopy. J Vis Exp. 2017 Sep 29; (127). PMID: 28994775.
- Published on 8/12/2017
Zuriaga MA, Fuster JJ, Maclauchlan S, Gokce N, Walsh K. Coordinated activation of WNT/planar cell polarity signaling in inflamed visceral fat of obese individuals. Atherosclerosis. 2017 Aug; 263:e8. PMID: 29366230.
- Published on 5/5/2017
Zuriaga MA, Fuster JJ, Gokce N, Walsh K. Humans and Mice Display Opposing Patterns of "Browning" Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots. Front Cardiovasc Med. 2017; 4:27. PMID: 28529941.
- Published on 4/14/2017
Karki S, Ngo DTM, Farb MG, Park SY, Saggese SM, Hamburg NM, Carmine B, Hess DT, Walsh K, Gokce N. WNT5A regulates adipose tissue angiogenesis via antiangiogenic VEGF-A165b in obese humans. Am J Physiol Heart Circ Physiol. 2017 Jul 01; 313(1):H200-H206. PMID: 28411232.
- Published on 9/28/2016
Farb MG, Karki S, Park SY, Saggese SM, Carmine B, Hess DT, Apovian C, Fetterman JL, Bretón-Romero R, Hamburg NM, Fuster JJ, Zuriaga MA, Walsh K, Gokce N. WNT5A-JNK regulation of vascular insulin resistance in human obesity. Vasc Med. 2016 Dec; 21(6):489-496. PMID: 27688298.
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