Natasha S. Hochberg, MD, MPH

Associate Professor, Medicine

Natasha Hochberg
715 Albany St Talbot Building

Biography

Natasha Hochberg, MD, MPH is Associate Professor in the Department of Medicine (Section of Infectious Diseases) at BU School of Medicine and in the Department of Epidemiology at BU School of Public Health. She is also the Program Director for the Infectious Disease Fellowship Program. Prior to her arrival at Boston University, Dr. Hochberg was an Epidemic Intelligence Service (EIS) officer at the Centers for Disease and Prevention (CDC) in the Division of Parasitic Diseases and worked internationally on projects related to malaria, visceral leishmaniasis, guinea worm disease, and lymphatic filariasis.

Dr. Hochberg’s current research focuses on tropical diseases. Particularly, she studies the impact of malnutrition and parasitic disease on tuberculosis (TB), tropical diseases in immigrant populations, and preventing diseases in international travelers. She is the principal investigator of the TB LION study (Learning the Impact Of Nutrition) in Pondicherry India. This study of household contacts of TB cases evaluates the impact of malnutrition and parasite infections on the immune response to TB and how this changes after providing a high-protein food package, multivitamin, and deworming. She is also site principal investigator of the the US-Indo RePORT study in Pondicherry, India, a cohort of 1100 TB patients and 1500 of their household contacts. The study aims to identify biomarkers that predict TB treatment failure and risk of developing TB (among exposed persons) and to identify how comorbidities (e.g., diabetes, helminth infections) modulate these profiles and risks. She is also the co-investigator of an R01 studying TB in pregnancy in India; the study looks at pharmacokinetics of TB drugs in pregnancy, assesses neonatal outcomes, and evaluates diagnostic testing for latent TB infection in pregnant women. She was the previous recipient of a K-12 BIRCWH award to study the effect of aging on the immune response to latent TB infection in Boston-area nursing home residents.

She is the co-director of the travel clinic at Boston Medical Center (BMC) where she sees travelers and patients with tropical diseases with a particular focus on Chagas disease and other parasitic infections. She serves as the co-site director for GeoSentinel, an international surveillance system of diseases in travelers and migrants, and participates in studies related to tropical medicine and travelers health. At a national level, she is part of the American Society of Tropical Medicine and Hygiene where she serves as a Councilor for the Clinical Group, as a member of the Scientific Program Committee, and as the Chair for the Subcommittee on Pneumonia, Respiratory Infections and TB. She also sees patients at the Center for Infectious Diseases and attends on the infectious disease consult service.

Dr. Hochberg has taught courses at BU School of Public Health on Infectious Disease Epidemiology (EP755) and Outbreak Investigations (EP800).

Other Positions

  • Associate Professor, Epidemiology, Boston University School of Public Health
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University

Education

  • Case School of Medicine, MD
  • Emory University, MPH
  • Harvard University, BA

Publications

  • Published on 3/21/2022

    Balogun O, Brown A, Angelo KM, Hochberg NS, Barnett ED, Nicolini LA, Asgeirsson H, Grobusch MP, Leder K, Salvador F, Chen L, Odolini S, Díaz-Menéndez M, Gobbi F, Connor BA, Libman M, Hamer DH. Acute hepatitis A in international travellers: a GeoSentinel analysis, 2008-2020. J Travel Med. 2022 03 21; 29(2). PMID: 35134210.

    Read at: PubMed
  • Published on 3/17/2022

    Carwile ME, Hochberg NS, Sinha P. Undernutrition is feeding the tuberculosis pandemic: A perspective. J Clin Tuberc Other Mycobact Dis. 2022 May; 27:100311. PMID: 35313724.

    Read at: PubMed
  • Published on 1/7/2022

    Kaipilyawar V, Zhao Y, Wang X, Joseph NM, Knudsen S, Babu SP, Muthaiah M, Hochberg NS, Sarkar S, Horsburgh CR, Ellner JJ, Johnson WE, Salgame P. Development and validation of a parsimonious TB gene signature using the digital NanoString nCounter platform. Clin Infect Dis. 2022 Jan 07. PMID: 35015839.

    Read at: PubMed
  • Published on 1/1/2022

    Sinha P, White LF, Hochberg NS, Cegielski JP. Avoiding pitfalls in calculating the population attributable fraction of undernutrition for TB. Int J Tuberc Lung Dis. 2022 01 01; 26(1):80. PMID: 34969436.

    Read at: PubMed
  • Published on 12/15/2021

    Sinha P, Lakshminarayanan SL, Cintron C, Narasimhan PB, Locks LM, Kulatilaka N, Maloomian K, Prakash Babu S, Carwile ME, Liu AF, Horsburgh CR, Acuna-Villaorduna C, Linas BP, Hochberg NS. Nutritional Supplementation Would Be Cost-Effective for Reducing Tuberculosis Incidence and Mortality in India: The Ration Optimization to Impede Tuberculosis (ROTI-TB) model. Clin Infect Dis. 2021 Dec 15. PMID: 34910141.

    Read at: PubMed
  • Published on 10/26/2021

    Krishnamoorthy Y, Ezhumalai K, Murali S, Rajaa S, Jose M, Sathishkumar A, Soundappan G, Horsburgh C, Hochberg N, Johnson WE, Knudsen S, Salgame P, Ellner J, Prakash Babu S, Sarkar S. Prevalence and risk factors associated with latent tuberculosis infection among household contacts of smear positive pulmonary tuberculosis patients in South India. Trop Med Int Health. 2021 12; 26(12):1645-1651. PMID: 34654061.

    Read at: PubMed
  • Published on 10/22/2021

    Rajaa S, Krishnamoorthy Y, Knudsen S, Roy G, Ellner J, Horsburgh CR, Hochberg NS, Salgame P, S G, Prakash Babu S, Sarkar S. Prevalence and factors associated with diabetes mellitus among tuberculosis patients in South India-a cross-sectional analytical study. BMJ Open. 2021 10 22; 11(10):e050542. PMID: 34686553.

    Read at: PubMed
  • Published on 10/16/2021

    Sabin LL, Thulasingam M, Carwile M, Babu SP, Knudsen S, Dong L, Stephens J, Fernandes P, Cintron C, Horsburgh CR, Salgame P, Ellner JJ, Sarkar S, Hochberg NS. 'People listen more to what actors say': A qualitative study of tuberculosis-related knowledge, behaviours, stigma, and potential interventions in Puducherry, India. Glob Public Health. 2021 Oct 16; 1-13. PMID: 34657567.

    Read at: PubMed
  • Published on 10/12/2021

    Cintron C, Narasimhan PB, Locks L, Babu S, Sinha P, Rajkumari N, Kaipilyawar V, Bhargava A, Maloomian K, Chandrasekaran P, Verma S, Joseph N, Johnson WE, Wanke C, Horsburgh CR, Ellner JJ, Sarkar S, Salgame P, Lakshminarayanan S, Hochberg NS. Tuberculosis-Learning the Impact of Nutrition (TB LION): protocol for an interventional study to decrease TB risk in household contacts. BMC Infect Dis. 2021 Oct 12; 21(1):1058. PMID: 34641820.

    Read at: PubMed
  • Published on 10/8/2021

    Forsyth CJ, Manne-Goehler J, Bern C, Whitman J, Hochberg NS, Edwards M, Marcus R, Beatty NL, Castro Y, Coyle C, Stigler-Granados P, Hamer D, Maguire JH, Gilman R, Meymandi S. Recommendations for Screening and Diagnosis of Chagas Disease in the United States. J Infect Dis. 2021 Oct 08. PMID: 34623435.

    Read at: PubMed

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