Michael F. Holick, MD, PhD

Professor, Medicine

Michael Holick
75 E. Newton St


Dr. Holick has made numerous contributions to the field of the biochemistry, physiology, metabolism, and photobiology of vitamin D for human nutrition. Dr. Holick has established global recommendations advising sunlight exposure as an integral source of vitamin D. He has helped increase awareness in the pediatric and medical communities regarding vitamin D deficiency pandemic, and its role in causing not only metabolic bone disease, and osteoporosis in adults, but increasing risk of children and adults developing preeclampsia, common deadly cancers, schizophrenia, infectious diseases including TB and influenza, autoimmune diseases including type 1 diabetes and multiple sclerosis, type 2 diabetes, stroke and heart disease.

Dr. Holick is a Diplomate of the American Board of Internal Medicine, a Fellow of the American College of Nutrition, and a member of the American Association of Physicians. He is the recipient of numerous awards and honors, including the General Clinical Research Centers Program Award for Excellence in Clinical Research from NIH, American College of Nutrition’s Communication Media Award, Best Docs in America, the Linus Pauling Functional Medicine Award from the Institute for Functional Medicine and the Linus Pauling Prize for Human Nutrition. Dr. Holick serves on a number of national committees and editorial boards and has organized and/or co-chaired several international symposia. He served as the chair for the Endocrine Society’s Practice Guidelines on Vitamin D. He has authored more than 400 peer-reviewed publications, and written more than 200 review articles, as well as numerous book chapters. He has acted as editor and/or co-editor on 13 books, and has written The UV Advantage in 2004 and The Vitamin D Solution in 2010 and helped develop the dminder.info app.

Other Positions

  • Professor, Physiology & Biophysics, Boston University Chobanian & Avedisian School of Medicine
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
  • Director, General Clinical Research Unit, Boston University Medical Campus
  • Director, Bone Health Care Clinic, Boston Medical Center
  • Director of the Vitamin D, Skin and Bone Research Laboratory, Endocrinology, Diabetes, Nutrition & Weight Management, Medicine, Boston University Chobanian & Avedisian School of Medicine


  • University of Wisconsin-Madison, MD
  • University of Wisconsin-Madison, PhD
  • University of Wisconsin-Madison, MS
  • Seton Hall University, BS

Classes Taught

  • GMSNU755
  • GMSNU757


  • Published on 8/1/2022

    Slominski AT, Kim TK, Slominski RM, Song Y, Janjetovic Z, Podgorska E, Reddy SB, Song Y, Raman C, Tang EKY, Fabisiak A, Brzeminski P, Sicinski RR, Atigadda V, Jetten AM, Holick MF, Tuckey RC. Metabolic activation of tachysterol3 to biologically active hydroxyderivatives that act on VDR, AhR, LXRs, and PPAR? receptors. FASEB J. 2022 Aug; 36(8):e22451. PMID: 35838947.

    Read at: PubMed
  • Published on 7/19/2022

    Charoenngam N, Ayoub D, Holick MF. Nutritional rickets and vitamin D deficiency: consequences and strategies for treatment and prevention. Expert Rev Endocrinol Metab. 2022 Jul 19; 1-14. PMID: 35852141.

    Read at: PubMed
  • Published on 5/14/2022

    Maghbooli Z, Mozaffari S, Dehghani Y, Rezaei Amirkiasar P, Malekhosseini AA, Rezanejad M, Holick MF. The lower basal metabolic rate is associated with increased risk of osteosarcopenia in postmenopausal women. BMC Womens Health. 2022 May 14; 22(1):171. PMID: 35568898.

    Read at: PubMed
  • Published on 4/10/2022

    Amon U, Yaguboglu R, Ennis M, Holick MF, Amon J. Safety Data in Patients with Autoimmune Diseases during Treatment with High Doses of Vitamin D3 According to the "Coimbra Protocol". Nutrients. 2022 Apr 10; 14(8). PMID: 35458137.

    Read at: PubMed
  • Published on 3/7/2022

    Menéndez SG, Martín Giménez VM, Holick MF, Barrantes FJ, Manucha W. COVID-19 and neurological sequelae: Vitamin D as a possible neuroprotective and/or neuroreparative agent. Life Sci. 2022 May 15; 297:120464. PMID: 35271880.

    Read at: PubMed
  • Published on 2/24/2022

    Holick MF. The CO-VID D-Lemma: A Call for Action. Nutrients. 2022 Feb 24; 14(5). PMID: 35267938.

    Read at: PubMed
  • Published on 1/4/2022

    Bae JH, Choe HJ, Holick MF, Lim S. Association of vitamin D status with COVID-19 and its severity : Vitamin D and COVID-19: a narrative review. Rev Endocr Metab Disord. 2022 06; 23(3):579-599. PMID: 34982377.

    Read at: PubMed
  • Published on 10/15/2021

    Charoenngam N, Holick MF. Marked Underestimation of Serum 25-hydroxyvitamin D Concentrations by The Abbot Architect Chemiluminescent Microparticle Immunoassay in Patients Receiving Vitamin D2 Supplementation. Endocr Pract. 2022 Jan; 28(1):122-123. PMID: 34656785.

    Read at: PubMed
  • Published on 10/13/2021

    Maghbooli Z, Sahraian MA, Jamalimoghadamsiahkali S, Asadi A, Zarei A, Zendehdel A, Varzandi T, Mohammadnabi S, Alijani N, Karimi M, Shirvani A, Holick MF. Treatment With 25-Hydroxyvitamin D3 (Calcifediol) Is Associated With a Reduction in the Blood Neutrophil-to-Lymphocyte Ratio Marker of Disease Severity in Hospitalized Patients With COVID-19: A Pilot Multicenter, Randomized, Placebo-Controlled, Double-Blinded Clinical Trial. Endocr Pract. 2021 Dec; 27(12):1242-1251. PMID: 34653608.

    Read at: PubMed
  • Published on 10/6/2021

    Martín Giménez VM, Lahore H, Ferder L, Holick MF, Manucha W. The little-explored therapeutic potential of nanoformulations of 1,25-dihydroxyvitamin D3 and its active analogs in prevalent inflammatory and oxidative disorders. Nanomedicine (Lond). 2021 11; 16(26):2327-2330. PMID: 34610750.

    Read at: PubMed

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