Mark B. Moss, PhD

Emeritus Professor, Anatomy & Neurobiology

Mark Moss
617.638.4200
72 E. Concord St Instructional (L)

Biography

Dr. Mark Moss is Emeritus Professor of Anatomy and Neurobiology at Boston University School of Medicine. Dr. Moss received his doctorate in Psychology from Northeastern University and completed postdoctoral training at Beth Israel Hospital, Harvard Medical School in Neuroanatomy and Neuropsychology. He joined the Department of Anatomy and Neurobiology in 1982 and has served as its Chairman since 1998. Together with Dr. Douglas Rosene, Dr. Moss is co-director for the Laboratory for Cognitive Neurobiology. His studies focus on the neurobiology of learning and memory in non-human primate models, particularly with respect to aging and age-related disease. Specific interests include (1) the interaction of the prefrontal cortices with the medial temporal lobe limbic system in cognition; (2) the separate and combined effects of age and hypertension on cognition and integrity of the blood-brain barrier in a non-human primate model of hypertensive cerebrovascular disease and (3) parallel studies in normal aged humans and patients with MCI and Alzheimer’s disease. Techniques include automated behavioral assessment, functional and structural MR imaging, and an array of immunocytochemical and related anatomical-morphological techniques.

He is recognized for his expertise on the neural basis of cognitive decline in aging and age-related disease, both in non-human primates and humans alike, and the development of “translational” tasks of cognition. He was Program Director for an NIA-NINDS Program Project studying the effects on brain integrity and cognition in a non-human primate model of hypertensive cerebrovascular disease. Dr. Moss is a recipient of an NIH MERIT award for his work on aging and hypertension.

Dr. Moss has directed the 1st year course in Medical Gross Anatomy and currently directs graduate courses in Cognitive Neuroscience, Professional Skills, and Grant Writing, and co-directs the course in the Neurobiology of Learning and Memory. He is the recipient of the Stanley L. Robbins Award, the highest teaching award at the School of Medicine, and is a recipient of the Thomas Robitscher Faculty Award for Excellence in Teaching.

Dr. Moss serves on a variety of scientific and administrative committees at the national, community, university, and medical school levels. He is also the academic advisor for the Clinical Neuroscience Society at BUSM.

Other Positions

  • Emeritus Professor, Neurology, Boston University School of Medicine
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences

Education

  • Northeastern University, PhD
  • Northeastern University, MA
  • University of Massachusetts Boston, BS

Publications

  • Published on 10/29/2018

    Brooks C, Eden G, Chang A, Demanuele C, Kelley Erb M, Shaafi Kabiri N, Moss M, Bhangu J, Thomas K. Quantification of discrete behavioral components of the MDS-UPDRS. J Clin Neurosci. 2019 Mar; 61:174-179. PMID: 30385169.

    Read at: PubMed
  • Published on 7/4/2018

    Koo BB, Calderazzo S, Bowley BGE, Kolli A, Moss MB, Rosene DL, Moore TL. Long-term effects of curcumin in the non-human primate brain. Brain Res Bull. 2018 09; 142:88-95. PMID: 29981358.

    Read at: PubMed
  • Published on 2/15/2018

    Moore TL, Bowley BGE, Shultz PL, Calderazzo SM, Shobin EJ, Uprety AR, Rosene DL, Moss MB. Oral curcumin supplementation improves fine motor function in the middle-aged rhesus monkey. Somatosens Mot Res. 2018 03; 35(1):1-10. PMID: 29447046.

    Read at: PubMed
  • Published on 11/21/2017

    Farrar DC, Mian AZ, Budson AE, Moss MB, Killiany RJ. Functional brain networks involved in decision-making under certain and uncertain conditions. Neuroradiology. 2018 Jan; 60(1):61-69. PMID: 29164280.

    Read at: PubMed
  • Published on 10/18/2017

    Moore TL, Bowley B, Shultz P, Calderazzo S, Shobin E, Killiany RJ, Rosene DL, Moss MB. Chronic curcumin treatment improves spatial working memory but not recognition memory in middle-aged rhesus monkeys. Geroscience. 2017 12; 39(5-6):571-584. PMID: 29047012.

    Read at: PubMed
  • Published on 7/10/2017

    Farrar DC, Mian AZ, Budson AE, Moss MB, Koo BB, Killiany RJ. Retained executive abilities in mild cognitive impairment are associated with increased white matter network connectivity. Eur Radiol. 2018 Jan; 28(1):340-347. PMID: 28695358.

    Read at: PubMed
  • Published on 1/25/2017

    Hainsworth AH, Allan SM, Boltze J, Cunningham C, Farris C, Head E, Ihara M, Isaacs JD, Kalaria RN, Lesnik Oberstein SA, Moss MB, Nitzsche B, Rosenberg GA, Rutten JW, Salkovic-Petrisic M, Troen AM. Translational models for vascular cognitive impairment: a review including larger species. BMC Med. 2017 Jan 25; 15(1):16. PMID: 28118831.

    Read at: PubMed
  • Published on 4/9/2014

    Fried PJ, Rushmore RJ, Moss MB, Valero-Cabré A, Pascual-Leone A. Causal evidence supporting functional dissociation of verbal and spatial working memory in the human dorsolateral prefrontal cortex. Eur J Neurosci. 2014 Jun; 39(11):1973-81. PMID: 24713032.

    Read at: PubMed
  • Published on 10/22/2012

    Moore TL, Schettler SP, Killiany RJ, Rosene DL, Moss MB. Impairment in delayed nonmatching to sample following lesions of dorsal prefrontal cortex. Behav Neurosci. 2012 Dec; 126(6):772-80. PMID: 23088539.

    Read at: PubMed
  • Published on 4/1/2011

    Moore TL, Killiany RJ, Pessina MA, Moss MB, Finklestein SP, Rosene DL. Recovery from ischemia in the middle-aged brain: a nonhuman primate model. Neurobiol Aging. 2012 Mar; 33(3):619.e9-619.e24. PMID: 21458887.

    Read at: PubMed

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