Mark H. Mirochnick, MD

Professor, Pediatrics

Mark Mirochnick

Biography

Mark Mirochnick, MD is Professor of Pediatrics and Chief of the Division of Neonatology at Boston University School of Medicine/Boston Medical Center. His main research involves investigating the effects of antiretrovirals in infants, children and pregnant women. He has served as protocol chair, investigator and/or protocol pharmacologist for HIV protocols on more than two continents. He currently serves as co-chair of the US Perinatal HIV Guidelines Committee and is a member of numerous Committees for HIV research including the WHO Pediatric Antiretroviral Working Group.

Other Positions

  • Section Director, Neonatology, Pediatrics, Boston University School of Medicine
  • Active Staff Privileges, Pediatrics, Boston Medical Center

Education

  • University of Vermont College of Medicine, MD
  • Dickinson College, BSc

Publications

  • Published on 12/1/2019

    Clarke DF, Mirochnick M, Acosta EP, Capparelli E, Chain A, Teppler H, Smith B, Lommerse J. Use of Modeling and Simulations to Determine Raltegravir Dosing in Neonates: A Model for Safely and Efficiently Determining Appropriate Neonatal Dosing Regimens: IMPAACT P1110. J Acquir Immune Defic Syndr. 2019 Dec 01; 82(4):392-398. PMID: 31658182.

    Read at: PubMed
  • Published on 9/13/2019

    Colbers A, Mirochnick M, Schalkwijk S, Penazzato M, Townsend C, Burger D. Importance of Prospective Studies in Pregnant and Breastfeeding Women Living With Human Immunodeficiency Virus. Clin Infect Dis. 2019 Sep 13; 69(7):1254-1258. PMID: 30783649.

    Read at: PubMed
  • Published on 9/6/2019

    Liu XI, Momper JD, Rakhmanina N, van den Anker JN, Green DJ, Burckart GJ, Best BM, Mirochnick M, Capparelli EV, Dallmann A. Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir. J Clin Pharmacol. 2019 Sep 06. PMID: 31489678.

    Read at: PubMed
  • Published on 8/9/2019

    Levesque BM, Burnham L, Cardoza N, Adams M, Cohen R, Mirochnick M, Fujii A, Sinha B. Improving Respiratory Support Practices to Reduce Chronic Lung Disease in Premature Infants. Pediatr Qual Saf. 2019 Jul-Aug; 4(4):e193. PMID: 31572894.

    Read at: PubMed
  • Published on 7/12/2019

    Nachman S, Townsend CL, Abrams EJ, Archary M, Capparelli E, Clayden P, Lockman S, Jean-Philippe P, Mayer K, Mirochnick M, McKenzie-White J, Struble K, Watts H, Flexner C. Long-acting or extended-release antiretroviral products for HIV treatment and prevention in infants, children, adolescents, and pregnant and breastfeeding women: knowledge gaps and research priorities. Lancet HIV. 2019 Aug; 6(8):e552-e558. PMID: 31307946.

    Read at: PubMed
  • Published on 7/10/2019

    Lommerse J, Clarke D, Kerbusch T, Merdjan H, Witjes H, Teppler H, Mirochnick M, Acosta EP, Wenning L, Nachman S, Chain A. Maternal-Neonatal Raltegravir Population Pharmacokinetics Modeling: Implications for Initial Neonatal Dosing. CPT Pharmacometrics Syst Pharmacol. 2019 Sep; 8(9):643-653. PMID: 31215170.

    Read at: PubMed
  • Published on 7/1/2019

    Momper JD, Hanan NJ, Rossi SS, Mirochnick MH, Cafferata ML, Lavenia A, Flores I, Gibbons L, Ciganda A, Sosa Estani S, Capparelli EV, Buekens P. Determination of Benznidazole in Human Dried Blood Spots by Liquid Chromatography-Mass Spectrometry to Monitor Adherence to Trypanosoma cruzi Infection Treatment in Infants and Children. Am J Trop Med Hyg. 2019 Jul; 101(1):116-122. PMID: 31115303.

    Read at: PubMed
  • Published on 6/11/2019

    Eke AC, Mirochnick M. Ritonavir and cobicistat as pharmacokinetic enhancers in pregnant women. Expert Opin Drug Metab Toxicol. 2019 Jul; 15(7):523-525. PMID: 31185758.

    Read at: PubMed
  • Published on 5/1/2019

    Schalkwijk S, Ter Heine R, Colbers A, Capparelli E, Best BM, Cressey TR, Greupink R, Russel FGM, Moltó J, Mirochnick M, Karlsson MO, Burger DM. Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling. J Antimicrob Chemother. 2019 May 01; 74(5):1348-1356. PMID: 30715324.

    Read at: PubMed
  • Published on 3/1/2019

    Eke AC, Mirochnick MH. Cobicistat as a Pharmacoenhancer in Pregnancy and Postpartum: Progress to Date and Next Steps. J Clin Pharmacol. 2019 Jun; 59(6):779-783. PMID: 30821843.

    Read at: PubMed

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