Marc E. Lenburg, PhD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Expertise in computational approaches to leverage genome-wide datasets (especially genome-wide gene-expression) for clinical and biological insight. Interests include developing and applying these tools for translational research.

Publications

  • Published 1/23/2026

    Okajima Y, Lenburg ME, Diaz AA. When Asthmatic Distal Airways Lose Their Identity: A New Mechanism of Mucus Plugs Pathogenesis. Am J Respir Crit Care Med. 2026 Jan 23. PMID: 41738085.

    Read at: PubMed

  • Published 10/10/2025

    Souery WN, Billatos E, Elalami R, San José Estépar R, Cho MH, Diaz AA, Lenburg ME. Mucus Plugs-associated Gene Expression Identifies Pathophysiology Shared with Chronic Bronchitis. Am J Respir Crit Care Med. 2025 Oct 10. PMID: 41072469.

    Read at: PubMed

  • Published 10/6/2025

    Anderson KE, Tran LM, Krysan K, Kefella Y, Yu L, Fishbein GA, Rodriguez E, Shabihkhani M, Stefanko DP, Green E, Liu G, Liu H, Zhang S, Kane E, Mehrad M, Spira AE, Dubinett SM, Burks EJ, Mazzilli SA, Lenburg ME, Beane JE. Archetype analysis of lung adenocarcinoma premalignancy links heterogeneity in premalignant lesions to diverging features of invasive disease. bioRxiv. 2025 Oct 06. PMID: 41278661.

    Read at: PubMed

  • Published 2/5/2025

    Ning B, Chiu DJ, Pfefferkorn RM, Kefella Y, Kane E, Reyes-Ortiz V, Liu G, Zhang S, Liu H, Sultan L, Green E, Constant M, Spira AE, Campbell JD, Reid ME, Varelas X, Burks EJ, Lenburg ME, Mazzilli SA, Beane JE. Epithelial miR-149-5p up-regulation is associated with immune evasion in progressive bronchial premalignant lesions. bioRxiv. 2025 Feb 05. PMID: 39975222.

    Read at: PubMed

  • Published 6/10/2024

    Steiner D, Sultan L, Sullivan T, Liu H, Zhang S, LeClerc A, Alekseyev YO, Liu G, Mazzilli SA, Zhang J, Rieger-Christ K, Burks EJ, Beane J, Lenburg ME. Identification of a gene expression signature of vascular invasion and recurrence in stage I lung adenocarcinoma via bulk and spatial transcriptomics. bioRxiv. 2024 Jun 10. PMID: 38915565.

    Read at: PubMed

Other Positions

  • Professor, Pathology & Laboratory Medicine
    Boston University Chobanian & Avedisian School of Medicine
  • Member, BU-BMC Cancer Center
    Boston University
  • Member, Pulmonary Center
    Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research
    Boston University
  • Member, Genome Science Institute
    Boston University
  • Member, Bioinformatics Graduate Program
    Boston University
  • Graduate Medical Sciences Educator and Mentor (Primary Mentor of Graduate Students)
    Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Education

  • University of California San Francisco, PhD
  • Wesleyan University, BA