Kalpana Gupta, MD

Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Gupta is Chief, Section of Infectious Diseases at the Veterans Administration Boston Healthcare System, and Professor of Medicine at Chobanian and Avedisian School of Medicine. Her primary research focus over the past decade has been on optimizing treatment regimens and prevention strategies for urinary tract infections (UTIs) in women. She is Chair of the IDSA UTI guideline update committee. She is currently PI of a multi-site NIH-funded randomized controlled trial of cranberry juice cocktail to prevent recurrent UTI in women and just completed a randomized trial of short course nitrofurantoin for treatment of acute cystitis in women. As a natural progression of her work on antimicrobial resistance in community-acquired UTIs, she is now embarking on a new research area, namely the evaluation of the prevalence and molecular epidemiology of MRSA infections in the veteran population.

Publications

  • Published 10/14/2026

    Trautner BW, Cortes-Penfield NW, Gupta K, Hirsch EB, Lavergne V. Oral Fosfomycin for Complicated Urinary Tract Infection Remains a Murky Issue. Clin Infect Dis. 2026 Oct 14. PMID: 42873548.

    Read at: PubMed

  • Published 9/1/2026

    Ramírez M, Gupta K, Díaz-Regañón J, Banerjee R, Bablani J, Powell D, Hankinson A, Janmohamed S. Gepotidacin and Early Symptom Improvement in Uncomplicated Urinary Tract Infection: A Nonrandomized Clinical Trial. JAMA Netw Open. 2026 Sep 01; 9(9):e2634116. PMID: 42809288.

    Read at: PubMed

  • Published 8/24/2026

    Trautner BW, Cortés-Penfield NW, Gupta K, Hirsch EB, Horstman M, Moran GJ, Colgan R, O'Horo JC, Ashraf MS, Connolly S, Drekonja D, Grigoryan L, Huttner A, Lazenby GB, Nicolle L, Schaeffer A, Yawetz S, Lavergne V. Clinical Practice Guidelines by Infectious Diseases Society of America 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections--Introduction and Methods. Clin Infect Dis. 2026 Aug 24; 82(Supplement_3):i24-i35. PMID: 41467387.

    Read at: PubMed

  • Published 8/24/2026

    Trautner BW, Cortés-Penfield NW, Gupta K, Hirsch EB, Horstman M, Moran GJ, Colgan R, O'Horo JC, Ashraf MS, Connolly S, Drekonja D, Grigoryan L, Huttner A, Lazenby GB, Nicolle L, Schaeffer A, Yawetz S, Lavergne V. Clinical Practice Guidelines by Infectious Diseases Society of America (IDSA): 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections--Duration of Antibiotics for Complicated UTI. Clin Infect Dis. 2026 Aug 24; 82(Suppl 3):i79-i88. PMID: 41419448.

    Read at: PubMed

  • Published 8/24/2026

    Trautner BW, Cortés-Penfield NW, Gupta K, Hirsch EB, Horstman M, Moran GJ, Colgan R, O'Horo JC, Ashraf MS, Connolly S, Drekonja D, Grigoryan L, Huttner A, Lazenby GB, Nicolle L, Schaeffer A, Yawetz S, Lavergne V. Clinical Practice Guidelines by Infectious Diseases Society of America: 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections - Timing of Intravenous to Oral Antibiotics Transition for Complicated Urinary Tract Infections. Clin Infect Dis. 2026 Aug 24; 82(Suppl 3):i68-i78. PMID: 41414903.

    Read at: PubMed

Education

  • Stony Brook University, MD
  • University of Washington School of Public Health, MPH
  • Stony Brook University, BA