Junghee Lee, PhD

Research Assistant Professor, Neurology

150 S Huntington Avenue


  • Kangwon National University, PhD
  • Kangwon National University, MS
  • Kangwon National University, BS


  • Published on 6/7/2017

    Lee J, Hwang YJ, Kim Y, Lee MY, Hyeon SJ, Lee S, Kim DH, Jang SJ, Im H, Min SJ, Choo H, Pae AN, Kim DJ, Cho KS, Kowall NW, Ryu H. Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's disease. Acta Neuropathol. 2017 Nov; 134(5):729-748. PMID: 28593442.

    Read at: PubMed
  • Published on 10/20/2016

    Lee J, Hyeon SJ, Im H, Ryu H, Kim Y, Ryu H. Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS. Exp Neurobiol. 2016 Oct; 25(5):233-240. PMID: 27790057.

    Read at: PubMed
  • Published on 7/1/2015

    Kim Y, Lee J, Ryu H. Modulation of autophagy by miRNAs. BMB Rep. 2015 Jul; 48(7):371-2. PMID: 26129673.

    Read at: PubMed
  • Published on 1/1/2015

    Kim Y, Kang YS, Lee NY, Kim KY, Hwang YJ, Kim HW, Rhyu IJ, Her S, Jung MK, Kim S, Lee CJ, Ko S, Kowall NW, Lee SB, Lee J, Ryu H. Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency. Autophagy. 2015; 11(5):796-811. PMID: 25946189.

    Read at: PubMed
  • Published on 1/1/2014

    Park E, Kim Y, Ryu H, Kowall NW, Lee J, Ryu H. Epigenetic mechanisms of Rubinstein-Taybi syndrome. Neuromolecular Med. 2014 Mar; 16(1):16-24. PMID: 24381114.

    Read at: PubMed
  • Published on 11/14/2013

    Hwang YJ, Han D, Kim KY, Min SJ, Kowall NW, Yang L, Lee J, Kim Y, Ryu H. ESET methylates UBF at K232/254 and regulates nucleolar heterochromatin plasticity and rDNA transcription. Nucleic Acids Res. 2014 Feb; 42(3):1628-43. PMID: 24234436.

    Read at: PubMed
  • Published on 10/31/2013

    Lee J, Hwang YJ, Ryu H, Kowall NW, Ryu H. Nucleolar dysfunction in Huntington's disease. Biochim Biophys Acta. 2014 Jun; 1842(6):785-90. PMID: 24184605.

    Read at: PubMed
  • Published on 10/1/2013

    Lee J, Hwang YJ, Kim KY, Kowall NW, Ryu H. Epigenetic mechanisms of neurodegeneration in Huntington's disease. Neurotherapeutics. 2013 Oct; 10(4):664-76. PMID: 24006238.

    Read at: PubMed
  • Published on 7/1/2013

    Lee JK, Shin JH, Hwang SG, Gwag BJ, McKee AC, Lee J, Kowall NW, Ryu H, Lim DS, Choi EJ. MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):12066-71. PMID: 23818595.

    Read at: PubMed
  • Published on 3/2/2013

    Lee J, Hwang YJ, Shin JY, Lee WC, Wie J, Kim KY, Lee MY, Hwang D, Ratan RR, Pae AN, Kowall NW, So I, Kim JI, Ryu H. Epigenetic regulation of cholinergic receptor M1 (CHRM1) by histone H3K9me3 impairs Ca(2+) signaling in Huntington's disease. Acta Neuropathol. 2013 May; 125(5):727-39. PMID: 23455440.

    Read at: PubMed

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