John H. Connor, PhD

Associate Professor, Microbiology

John Connor
617.638.0339
72 E. Concord St Housman (R)

Biography

My laboratory studies the virus-host interaction. We take a variety of approaches from genetic to systems biology to biochemistry and molecular biology. We are studying how viruses take over the cellular protein synthesis apparatus, how cells effectively fight virus infection, and how the host responds to infection with viruses that cause hemorrhagic fever.

Other Positions

  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences
  • Member, Bioinformatics Graduate Program, Boston University

Education

  • Duke University, PhD
  • Swarthmore College, BA

Publications

  • Published on 9/26/2018

    Olsen ME, Cressey TN, Mühlberger E, Connor JH. Differential Mechanisms for the Involvement of Polyamines and Hypusinated eIF5A in Ebola Virus Gene Expression. J Virol. 2018 Oct 15; 92(20). PMID: 30045993.

    Read at: PubMed
  • Published on 9/12/2018

    Ruedas JB, Arnold CE, Palacios G, Connor JH. Growth-Adaptive Mutations in the Ebola Virus Makona Glycoprotein Alter Different Steps in the Virus Entry Pathway. J Virol. 2018 10 01; 92(19). PMID: 30021890.

    Read at: PubMed
  • Published on 7/6/2018

    Speranza E, Ruibal P, Port JR, Feng F, Burkhardt L, Grundhoff A, Günther S, Oestereich L, Hiscox JA, Connor JH, Muñoz-Fontela C. T-Cell Receptor Diversity and the Control of T-Cell Homeostasis Mark Ebola Virus Disease Survival in Humans. J Infect Dis. 2018 Jul 06. PMID: 29986035.

    Read at: PubMed
  • Published on 6/5/2018

    Olsen ME, Filone CM, Rozelle D, Mire CE, Agans KN, Hensley L, Connor JH. Correction for Olsen et al., "Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication". MBio. 2018 Jun 05; 9(3). PMID: 29871921.

    Read at: PubMed
  • Published on 5/22/2018

    Schultz MJ, Tan AL, Gray CN, Isern S, Michael SF, Frydman HM, Connor JH. Wolbachia wStri Blocks Zika Virus Growth at Two Independent Stages of Viral Replication. MBio. 2018 May 22; 9(3). PMID: 29789369.

    Read at: PubMed
  • Published on 4/3/2018

    Schultz MJ, Frydman HM, Connor JH. Dual Insect specific virus infection limits Arbovirus replication in Aedes mosquito cells. Virology. 2018 05; 518:406-413. PMID: 29625404.

    Read at: PubMed
  • Published on 3/28/2018

    Speranza E, Bixler SL, Altamura LA, Arnold CE, Pratt WD, Taylor-Howell C, Burrows C, Aguilar W, Rossi F, Shamblin JD, Wollen SE, Zelko JM, Minogue T, Nagle E, Palacios G, Goff AJ, Connor JH. A conserved transcriptional response to intranasal Ebola virus exposure in nonhuman primates prior to onset of fever. Sci Transl Med. 2018 Mar 28; 10(434). PMID: 29593102.

    Read at: PubMed
  • Published on 1/3/2018

    Schultz MJ, Connor JH, Frydman HM. Group B Wolbachia Strain-Dependent Inhibition of Arboviruses. DNA Cell Biol. 2018 Jan; 37(1):2-6. PMID: 29297702.

    Read at: PubMed
  • Published on 11/7/2017

    Speranza E, Altamura LA, Kulcsar K, Bixler SL, Rossi CA, Schoepp RJ, Nagle E, Aguilar W, Douglas CE, Delp KL, Minogue TD, Palacios G, Goff AJ, Connor JH. Comparison of Transcriptomic Platforms for Analysis of Whole Blood from Ebola-Infected Cynomolgus Macaques. Sci Rep. 2017 Nov 07; 7(1):14756. PMID: 29116224.

    Read at: PubMed
  • Published on 9/22/2017

    Lo J, Zhang D, Speranza E, Negron JA, Connor JH. HoTResDB: Host Transcriptional Response Database for Viral Hemorrhagic Fevers. Bioinformatics. 2017 Sep 22. PMID: 29028885.

    Read at: PubMed

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