Joanne M. Murabito, MD

Associate Professor, Medicine

Joanne Murabito
Framingham Heart Study 73 Mt Wayte Ave

Biography

Dr. Murabito is an Associate Professor of Medicine at Boston University School of Medicine and Co-PI at the Framingham Heart Study. Dr Murabito’s area of expertise is in epidemiology and genetic epidemiology. Her current research focuses on identifying the determinants of healthy aging and longevity and reproductive aging in the community including the investigation of genetic and genomic factors. She leads highly productive multidisciplinary international consortia including the Cohorts for Heart and Aging Research in Genomics Epidemiology (CHARGE) Aging and Longevity working group and the ReproGen Consortium. The Consortia bring together scientists interested in aging, longevity, and reproductive aging (menarche, menopause) and the relation of these traits to health outcomes and gene discovery.
Dr Murabito is also leading the introduction of mobile health into the Framingham Heart Study. She participated in an embedded physical activity trial using a smartphone app or activity tracker and would like to explore use of mHealth in older adults to improve health and function
Dr. Murabito continues to practice primary care at Boston Medical Center.

Other Positions

  • Research Center Director, Framingham Heart Study
  • Co-Principal Investigator, Framingham Heart Study

Education

  • Mount Sinai School of Medicine, MD
  • Harvard University, ScM
  • University of Rochester, BA

Publications

  • Published on 7/14/2018

    Lin H, Lunetta KL, Zhao Q, Mandaviya PR, Rong J, Benjamin EJ, Joehanes R, Levy D, van Meurs JBJ, Larson MG, Murabito JM. Whole Blood Gene Expression Associated with Clinical Biological Age. J Gerontol A Biol Sci Med Sci. 2018 Jul 14. PMID: 30010802.

    Read at: PubMed
  • Published on 6/18/2018

    Orkaby AR, Lunetta KL, Sun FJ, Driver JA, Benjamin EJ, Hamburg NM, Mitchell GF, Vasan RS, Murabito JM. Cross-Sectional Association of Frailty and Arterial Stiffness In Community-Dwelling Older Adults: The Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2018 Jun 18. PMID: 29917058.

    Read at: PubMed
  • Published on 5/9/2018

    Murabito JM, Zhao Q, Larson MG, Rong J, Lin H, Benjamin EJ, Levy D, Lunetta KL. Measures of Biologic Age in a Community Sample Predict Mortality and Age-Related Disease: The Framingham Offspring Study. J Gerontol A Biol Sci Med Sci. 2018 May 09; 73(6):757-762. PMID: 28977464.

    Read at: PubMed
  • Published on 4/24/2018

    Mendelson MM, Johannes R, Liu C, Huan T, Yao C, Miao X, Murabito JM, Dupuis J, Levy D, Benjamin EJ, Lin H. Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study. Front Pharmacol. 2018; 9:207. PMID: 29740313.

    Read at: PubMed
  • Published on 4/1/2018

    Sarnowski C, Kavousi M, Isaacs S, Demerath EW, Broer L, Muka T, Franco OH, Ikram MA, Uitterlinden A, Franceschini N, Lunetta KL, Murabito JM. Genetic variants associated with earlier age at menopause increase the risk of cardiovascular events in women. Menopause. 2018 Apr; 25(4):451-457. PMID: 29112599.

    Read at: PubMed
  • Published on 4/1/2018

    Haljas K, Amare AT, Alizadeh BZ, Hsu YH, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, Ding J, Llewellyn DJ, Bennett DA, Terracciano A, Launer L, Ladwig KH, Cornelis MC, Teumer A, Grabe H, Kardia SLR, Ware EB, Smith JA, Snieder H, Eriksson JG, Groop L, Räikkönen K, Lahti J. Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits. Psychosom Med. 2018 Apr; 80(3):242-251. PMID: 29280852.

    Read at: PubMed
  • Published on 3/1/2018

    Eriksson AL, Perry JRB, Coviello AD, Delgado GE, Ferrucci L, Hoffman AR, Huhtaniemi IT, Ikram MA, Karlsson MK, Kleber ME, Laughlin GA, Liu Y, Lorentzon M, Lunetta KL, Mellström D, Murabito JM, Murray A, Nethander M, Nielson CM, Prokopenko I, Pye SR, Raffel LJ, Rivadeneira F, Srikanth P, Stolk L, Teumer A, Travison TG, Uitterlinden AG, Vaidya D, Vanderschueren D, Zmuda JM, März W, Orwoll ES, Ouyang P, Vandenput L, Wu FCW, de Jong FH, Bhasin S, Kiel DP, Ohlsson C. Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men. J Clin Endocrinol Metab. 2018 03 01; 103(3):991-1004. PMID: 29325096.

    Read at: PubMed
  • Published on 2/15/2018

    Beaumont RN, Warrington NM, Cavadino A, Tyrrell J, Nodzenski M, Horikoshi M, Geller F, Myhre R, Richmond RC, Paternoster L, Bradfield JP, Kreiner-Møller E, Huikari V, Metrustry S, Lunetta KL, Painter JN, Hottenga JJ, Allard C, Barton SJ, Espinosa A, Marsh JA, Potter C, Zhang G, Ang W, Berry DJ, Bouchard L, Das S, Hakonarson H, Heikkinen J, Helgeland Ø, Hocher B, Hofman A, Inskip HM, Jones SE, Kogevinas M, Lind PA, Marullo L, Medland SE, Murray A, Murray JC, Njølstad PR, Nohr EA, Reichetzeder C, Ring SM, Ruth KS, Santa-Marina L, Scholtens DM, Sebert S, Sengpiel V, Tuke MA, Vaudel M, Weedon MN, Willemsen G, Wood AR, Yaghootkar H, Muglia LJ, Bartels M, Relton CL, Pennell CE, Chatzi L, Estivill X, Holloway JW, Boomsma DI, Montgomery GW, Murabito JM, Spector TD, Power C, Järvelin MR, Bisgaard H, Grant SFA, Sørensen TIA, Jaddoe VW, Jacobsson B, Melbye M, McCarthy MI, Hattersley AT, Hayes MG, Frayling TM, Hivert MF, Felix JF, Hyppönen E, Lowe WL, Evans DM, Lawlor DA, Feenstra B, Freathy RM. Genome-wide association study of offspring birth weight in 86?577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Hum Mol Genet. 2018 02 15; 27(4):742-756. PMID: 29309628.

    Read at: PubMed
  • Published on 1/26/2018

    Lu AT, Xue L, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou L, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S. GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nat Commun. 2018 Jan 26; 9(1):387. PMID: 29374233.

    Read at: PubMed
  • Published on 11/11/2017

    Lin H, Lunetta KL, Zhao Q, Rong J, Benjamin EJ, Mendelson MM, Joehanes R, Levy D, Larson MG, Murabito JM. Transcriptome-wide association study of inflammatory biologic age. Aging (Albany NY). 2017 Nov 11; 9(11):2288-2301. PMID: 29135455.

    Read at: PubMed

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