Jeffrey Boone Miller, PhD
Emeritus Professor, Neurology
Biography
His research interests are identifying pathogenetic mechanisms and developing new therapeutic strategies for neuromuscular diseases.
Other Positions
- Professor, Pharmacology, Physiology & Biophysics, Boston University Chobanian & Avedisian School of Medicine
- Member, Whitaker Cardiovascular Institute, Boston University
Education
- University of California, Berkeley, PhD
- Washington State University, BS
Publications
- Published on 5/10/2022
Beermann ML, Homma S, Miller JB. Proximity ligation assay to detect DUX4 protein in FSHD1 muscle: a pilot study. BMC Res Notes. 2022 May 10; 15(1):163. PMID: 35538497.
Read at: PubMed - Published on 2/15/2022
Masteika IF, Sathya A, Homma S, Miller BM, Boyce FM, Miller JB. Downstream events initiated by expression of FSHD-associated DUX4: Studies of nucleocytoplasmic transport, ?H2AX accumulation, and Bax/Bak-dependence. Biol Open. 2022 02 15; 11(2). PMID: 35191484.
Read at: PubMed - Published on 2/19/2019
Mitsuhashi H, Homma S, Beermann ML, Ishimaru S, Takeda H, Yu BK, Liu K, Duraiswamy S, Boyce FM, Miller JB. Efficient system for upstream mRNA trans-splicing to generate covalent, head-to-tail, protein multimers. Sci Rep. 2019 02 19; 9(1):2274. PMID: 30783185.
Read at: PubMed - Published on 4/26/2018
Mitsuhashi H, Ishimaru S, Homma S, Yu B, Honma Y, Beermann ML, Miller JB. Functional domains of the FSHD-associated DUX4 protein. Biol Open. 2018 Apr 26; 7(4). PMID: 29618456.
Read at: PubMed - Published on 1/1/2018
Yoon S, Beermann ML, Yu B, Shao D, Bachschmid M, Miller JB. Aberrant Caspase Activation in Laminin-a2-Deficient Human Myogenic Cells is Mediated by p53 and Sirtuin Activity. J Neuromuscul Dis. 2018; 5(1):59-73. PMID: 29278895.
Read at: PubMed - Published on 12/1/2016
Homma S, Beermann ML, Yu B, Boyce FM, Miller JB. Nuclear bodies reorganize during myogenesis in vitro and are differentially disrupted by expression of FSHD-associated DUX4. Skelet Muscle. 2016 Dec 01; 6(1):42. PMID: 27906075.
Read at: PubMed - Published on 3/29/2015
Jones TI, King OD, Himeda CL, Homma S, Chen JC, Beermann ML, Yan C, Emerson CP, Miller JB, Wagner KR, Jones PL. Individual epigenetic status of the pathogenic D4Z4 macrosatellite correlates with disease in facioscapulohumeral muscular dystrophy. Clin Epigenetics. 2015; 7(1):37. PMID: 25904990.
Read at: PubMed - Published on 1/15/2015
Homma S, Beermann ML, Boyce FM, Miller JB. Expression of FSHD-related DUX4-FL alters proteostasis and induces TDP-43 aggregation. Ann Clin Transl Neurol. 2015 Feb; 2(2):151-66. PMID: 25750920.
Read at: PubMed - Published on 3/17/2014
Himeda CL, Debarnot C, Homma S, Beermann ML, Miller JB, Jones PL, Jones TI. Myogenic enhancers regulate expression of the facioscapulohumeral muscular dystrophy-associated DUX4 gene. Mol Cell Biol. 2014 Jun; 34(11):1942-55. PMID: 24636994.
Read at: PubMed - Published on 12/6/2013
Yoon S, Stadler G, Beermann ML, Schmidt EV, Windelborn JA, Schneiderat P, Wright WE, Miller JB. Immortalized myogenic cells from congenital muscular dystrophy type1A patients recapitulate aberrant caspase activation in pathogenesis: a new tool for MDC1A research. Skelet Muscle. 2013; 3(1):28. PMID: 24314268.
Read at: PubMed
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