Jan K. Blusztajn, PhD
Professor, Pathology & Laboratory Medicine
Biography
Jan K. Blusztajn, PhD is a Professor of Pathology in the Department of Pathology & Laboratory Medicine at the Chobanian and Avedisian School of Medicine. Dr. Blusztajn received his PhD in Neural and Endocrine Regulation from the Massachusetts Institute of Technology. Dr. Blusztajn’s research is in prenatal programming of brain development and aging by essential nutrient availability during gestation.
Other Positions
- Research Professor, Psychiatry, Boston University Chobanian & Avedisian School of Medicine
- Member, BU-BMC Cancer Center, Boston University
- Investigator, Framingham Heart Study
- Member, Evans Center for Interdisciplinary Biomedical Research, Boston University
- Member, Genome Science Institute, Boston University
- Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Education
- Massachusetts Institute of Technology, PhD
- University of Warsaw, MS
Publications
- Published on 9/18/2024
Liu S, Park T, Krüger DM, Pena-Centeno T, Burkhardt S, Schutz AL, Huang YN, Rosewood T, Chaudhuri S, Cho M, Risacher SL, Wan Y, Shaw LM, Sananbenesi F, Brodsky AS, Lin H, Krunic A, Blusztajn JK, Saykin AJ, Delalle I, Fischer A, Nho K. Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers. Alzheimers Dement. 2024 Nov; 20(11):7698-7714. PMID: 39291737.
Read at: PubMed - Published on 9/18/2024
Krüger DM, Pena-Centeno T, Liu S, Park T, Kaurani L, Pradhan R, Huang YN, Risacher SL, Burkhardt S, Schütz AL, Wan Y, Shaw LM, Brodsky AS, DeStefano AL, Lin H, Schroeder R, Krunic A, Hempel N, Sananbenesi F, Blusztajn JK, Saykin AJ, Delalle I, Nho K, Fischer A. The plasma miRNAome in ADNI: Signatures to aid the detection of at-risk individuals. Alzheimers Dement. 2024 Nov; 20(11):7479-7494. PMID: 39291752.
Read at: PubMed - Published on 2/5/2024
Bellio TA, Laguna-Torres JY, Campion MS, Chou J, Yee S, Blusztajn JK, Mellott TJ. Perinatal choline supplementation prevents learning and memory deficits and reduces brain amyloid Aß42 deposition in AppNL-G-F Alzheimer's disease model mice. PLoS One. 2024; 19(2):e0297289. PMID: 38315685.
Read at: PubMed - Published on 1/15/2024
Obeid R, Schön C, Derbyshire E, Jiang X, Mellott TJ, Blusztajn JK, Zeisel SH. A Narrative Review on Maternal Choline Intake and Liver Function of the Fetus and the Infant; Implications for Research, Policy, and Practice. Nutrients. 2024 Jan 15; 16(2). PMID: 38257153.
Read at: PubMed - Published on 2/10/2023
Yuan J, Liu X, Liu C, Ang AF, Massaro J, Devine SA, Auerbach SH, Blusztajn JK, Au R, Jacques PF. Is dietary choline intake related to dementia and Alzheimer's disease risks? Results from the Framingham Heart Study. Am J Clin Nutr. 2022 Nov; 116(5):1201-1207. PMID: 37208066.
Read at: PubMed - Published on 1/1/2023
Blusztajn JK, Aytan N, Rajendiran T, Mellott TJ, Soni T, Burant CF, Serrano GE, Beach TG, Lin H, Stein TD. Cerebral Gray and White Matter Monogalactosyl Diglyceride Levels Rise with the Progression of Alzheimer's Disease. J Alzheimers Dis. 2023; 95(4):1623-1634. PMID: 37718815.
Read at: PubMed - Published on 1/1/2023
Blusztajn JK, Slack BE. Accelerated Breakdown of Phosphatidylcholine and Phosphatidylethanolamine Is a Predominant Brain Metabolic Defect in Alzheimer's Disease. J Alzheimers Dis. 2023; 93(4):1285-1289. PMID: 37182883.
Read at: PubMed - Published on 10/23/2021
Zhang Z, Na H, Gan Q, Tao Q, Alekseyev Y, Hu J, Yan Z, Yang JB, Tian H, Zhu S, Li Q, Rajab IM, Blusztajn JK, Wolozin B, Emili A, Zhang X, Stein T, Potempa LA, Qiu WQ. Monomeric C-reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype-dependent pattern: A risk factor for Alzheimer's disease? Aging Cell. 2021 11; 20(11):e13501. PMID: 34687487.
Read at: PubMed - Published on 2/1/2021
Kanach C, Blusztajn JK, Fischer A, Delalle I. MicroRNAs as Candidate Biomarkers for Alzheimer's Disease. Noncoding RNA. 2021 Feb 01; 7(1). PMID: 33535543.
Read at: PubMed - Published on 7/28/2020
Anderson KE, Bellio TA, Aniskovich E, Adams SL, Blusztajn JK, Delalle I. The Expression of Activin Receptor-Like Kinase 1 (ACVRL1/ALK1) in Hippocampal Arterioles Declines During Progression of Alzheimer's Disease. Cereb Cortex Commun. 2020; 1(1):tgaa031. PMID: 32974611.
Read at: PubMed
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