Jacqueline Sharon, PhD

Professor, Pathology & Laboratory Medicine

Jacqueline Sharon
617.638.4652
670 Albany St Biosquare III

Other Positions

  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences
  • Research Associate Professor, Biochemistry, Boston University School of Medicine

Education

  • Columbia University, PhD
  • Columbia University, MPhil
  • Queens College, City University of New York, MA
  • Queens College, City University of New York, BA

Publications

  • Published on 8/1/2014

    Lu Z, Rynkiewicz MJ, Yang CY, Madico G, Perkins HM, Roche MI, Seaton BA, Sharon J. Functional and structural characterization of Francisella tularensis O-antigen antibodies at the low end of antigen reactivity. Monoclon Antib Immunodiagn Immunother. 2014 Aug; 33(4):235-45. PMID: 25171003.

    Read at: PubMed
  • Published on 6/26/2014

    Lu Z, Rynkiewicz MJ, Madico G, Li S, Yang CY, Perkins HM, Sompuram SR, Kodela V, Liu T, Morris T, Wang D, Roche MI, Seaton BA, Sharon J. B-cell epitopes in GroEL of Francisella tularensis. PLoS One. 2014; 9(6):e99847. PMID: 24968190.

    Read at: PubMed
  • Published on 5/1/2014

    Sharon J, Rynkiewicz MJ, Lu Z, Yang CY. Discovery of protective B-cell epitopes for development of antimicrobial vaccines and antibody therapeutics. Immunology. 2014 May; 142(1):1-23. PMID: 24219801.

    Read at: PubMed
  • Published on 12/18/2013

    Lu Z, Perkins HM, Sharon J. Antibodies to both terminal and internal B-cell epitopes of Francisella tularensis O-polysaccharide produced by patients with tularemia. Clin Vaccine Immunol. 2014 Feb; 21(2):227-33. PMID: 24351753.

    Read at: PubMed
  • Published on 11/1/2013

    Lu Z, Rynkiewicz MJ, Yang CY, Madico G, Perkins HM, Wang Q, Costello CE, Zaia J, Seaton BA, Sharon J. The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide. Immunology. 2013 Nov; 140(3):374-89. PMID: 23844703.

    Read at: PubMed
  • Published on 7/2/2012

    Rynkiewicz MJ, Lu Z, Hui JH, Sharon J, Seaton BA. Structural analysis of a protective epitope of the Francisella tularensis O-polysaccharide. Biochemistry. 2012 Jul 17; 51(28):5684-94. PMID: 22747335.

    Read at: PubMed
  • Published on 7/1/2012

    Lu Z, Madico G, Roche MI, Wang Q, Hui JH, Perkins HM, Zaia J, Costello CE, Sharon J. Protective B-cell epitopes of Francisella tularensis O-polysaccharide in a mouse model of respiratory tularaemia. Immunology. 2012 Jul; 136(3):352-60. PMID: 22486311.

    Read at: PubMed
  • Published on 11/28/2011

    Wang Q, Shi X, Leymarie N, Madico G, Sharon J, Costello CE, Zaia J. A typical preparation of Francisella tularensis O-antigen yields a mixture of three types of saccharides. Biochemistry. 2011 Dec 20; 50(50):10941-50. PMID: 22091710.

    Read at: PubMed
  • Published on 2/1/2011

    Roche MI, Lu Z, Hui JH, Sharon J. Characterization of monoclonal antibodies to terminal and internal O-antigen epitopes of Francisella tularensis lipopolysaccharide. Hybridoma (Larchmt). 2011 Feb; 30(1):19-28. PMID: 21466282.

    Read at: PubMed
  • Published on 9/17/2007

    Liebman MA, Roche MI, Williams BR, Kim J, Pageau SC, Sharon J. Antibody treatment of human tumor xenografts elicits active anti-tumor immunity in nude mice. Immunol Lett. 2007 Nov 30; 114(1):16-22. PMID: 17920694.

    Read at: PubMed

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