Hugo Javier Aparicio, MD, MPH

Assistant Professor, Neurology

Hugo Aparicio
72 E. Concord St Robinson (B)


Dr. Aparicio’s research interests include the identification of lifestyle risk factors, biomarkers, neuroimaging markers and genetic influences associated with cerebrovascular diseases. He is particularly interested in the contributions of vascular risk factors to stroke, brain injury and aging, cognitive dysfunction and the development of Alzheimer’s disease and the influence of racial and ethnic disparities on these outcomes.

Other Positions

  • Investigator, Framingham Heart Study


  • University of Pennsylvania School of Medicine, MD
  • Emory University, BA


  • Published on 1/30/2023

    DeCarli C, Pase M, Beiser A, Kojis D, Satizabal C, Himali J, Aparicio H, Flether E, Maillard P, Seshadri S. Secular Trends in Head Size and Cerebral Volumes In the Framingham Heart Study for Birth Years 1902-1985. Res Sq. 2023 Jan 30. PMID: 36778357.

    Read at: PubMed
  • Published on 10/21/2022

    Morrison MS, Aparicio HJ, Blennow K, Zetterberg H, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Sugarman MA, Frank B, Steinberg EG, Turk KW, Budson AE, Au R, Goldstein LE, Jun GR, Kowall NW, Killiany R, Qiu WQ, Stern RA, Mez J, McKee AC, Stein TD, Alosco ML. Ante-mortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy. Brain. 2022 Oct 21; 145(10):3546-3557. PMID: 35554506.

    Read at: PubMed
  • Published on 10/5/2022

    Satizabal CL, Himali JJ, Beiser AS, Ramachandran V, Melo van Lent D, Himali D, Aparicio HJ, Maillard P, DeCarli CS, Harris W, Seshadri S. Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in Midlife: The Framingham Heart Study. Neurology. 2022 Oct 05; 99(23):e2572-82. PMID: 36198518.

    Read at: PubMed
  • Published on 9/30/2022

    Klein P, Shu L, Nguyen TN, Siegler JE, Omran SS, Simpkins AN, Heldner M, Havenon A, Aparicio HJ, Abdalkader M, Psychogios M, Vedovati MC, Paciaroni M, Martial RV, Liebeskind DS, Sousa DA, Coutinho JM, Yaghi S. Outcome Prediction in Cerebral Venous Thrombosis: The IN-REvASC Score. J Stroke. 2022 Sep; 24(3):404-416. PMID: 36221944.

    Read at: PubMed
  • Published on 9/29/2022

    Romero JR, Pinheiro A, Aparicio HJ, DeCarli CS, Demissie S, Seshadri S. MRI Visible Perivascular Spaces and Risk of Incident Dementia: The Framingham Heart Study. Neurology. 2022 Sep 29; 99(23):e2561-71. PMID: 36175148.

    Read at: PubMed
  • Published on 9/19/2022

    Shu L, Bakradze E, Omran SS, Giles J, Amar J, Henninger N, Elnazeir M, Liberman A, Moncrieffe K, Rotblat J, Sharma R, Cheng Y, Zubair AS, Simpkins A, Li G, Kung J, Perez D, Heldner MR, Scutelnic A, von Martial R, Siepen B, Rothstein A, Khazaal O, Do D, Al Kasab S, Rahman LA, Mistry EA, Kerrigan D, Lafever H, Nguyen TN, Klein P, Aparicio HJ, Frontera JA, Kuohn L, Agarwal S, Stretz C, Kala N, ElJamal S, Chang A, Cutting S, Indraswari F, de Havenon A, Muddasani V, Wu T, Wilson D, Nouh A, Asad D, Qureshi A, Moore J, Khatri P, Aziz Y, Casteigne B, Khan M, Cheng Y, Grory BM, Weiss M, Ryan D, Vedovati MC, Paciaroni M, Siegler J, Kamen S, Yu S, Guerrero CL, Atallah E, De Marchis GM, Brehm A, Dittrich T, Psychogios M, Alvarado-Dyer R, Kass-Hout T, Prabhakaran S, Honda T, Liebeskind D, Furie K, Yaghi S. Predictors of Recurrent Venous Thrombosis After Cerebral Venous Thrombosis: Analysis of the ACTION-CVT Study. Neurology. 2022 Nov 22; 99(21):e2368-e2377. PMID: 36123126.

    Read at: PubMed
  • Published on 9/3/2022

    Gonzales MM, Wiedner C, Wang CP, Liu Q, Bis JC, Li Z, Himali JJ, Ghosh S, Thomas EA, Parent DM, Kautz TF, Pase MP, Aparicio HJ, Djoussé L, Mukamal KJ, Psaty BM, Longstreth WT, Mosley TH, Gudnason V, Mbangdadji D, Lopez OL, Yaffe K, Sidney S, Bryan RN, Nasrallah IM, DeCarli CS, Beiser AS, Launer LJ, Fornage M, Tracy RP, Seshadri S, Satizabal CL. A population-based meta-analysis of circulating GFAP for cognition and dementia risk. Ann Clin Transl Neurol. 2022 Oct; 9(10):1574-1585. PMID: 36056631.

    Read at: PubMed
  • Published on 6/3/2022

    Al-Ramady O, Latifi AN, Treu T, Ho YL, Seshadri S, Aparicio HJ, Cho K, Wilson PW, Gaziano JM, Djoussé L. Egg consumption and risk of acute stroke in the Million Veteran Program. Clin Nutr ESPEN. 2022 Aug; 50:178-182. PMID: 35871921.

    Read at: PubMed
  • Published on 6/1/2022

    Tarko L, Costa L, Galloway A, Ho YL, Gagnon D, Lioutas V, Seshadri S, Cho K, Wilson P, Aparicio HJ. Racial and Ethnic Differences in Short- and Long-term Mortality by Stroke Type. Neurology. 2022 Jun 01. PMID: 35649728.

    Read at: PubMed
  • Published on 3/1/2022

    Angoff R, Himali JJ, Maillard P, Aparicio HJ, Vasan RS, Seshadri S, Beiser AS, Tsao CW. Relations of Metabolic Health and Obesity to Brain Aging in Young to Middle-Aged Adults. J Am Heart Assoc. 2022 03 15; 11(6):e022107. PMID: 35229662.

    Read at: PubMed

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