Hiroshi Mashimo, MD, PhD

Adjunct Assistant Professor, Medicine

Hiroshi Mashimo
72 E. Concord St Building A


Hiroshi Mashimo is currently Chief of Gastroenterology at the VA Boston Healthcare System, Assistant Professor of Medicine at Harvard Medical School and Adjunct Assistant Professor Of Medicine at Boston University School of Medicine. He obtained his A.B. at Harvard College and his M.S., M.D. and Ph.D. degrees at Albert Einstein College of Medicine. He completed his medical internship, residency, and gastroenterology fellowship at Massachusetts General Hospital. His interest in molecular physiology led to advanced research and clinical training at Harvard Medical School, with Dr Daniel K. Podolsky and Dr Mark C. Fishman at Massachusetts General Hospital, and with Dr Raj K. Goyal at Beth Israel Hospital. His pioneering work using genetically altered mice models to understand basic gastrointestinal physiology has led to important understandings of the distinct roles of various mediators such as nitric oxide synthases and vasoactive intestinal peptides in the field of gastrointestinal motility. He has continued his interest in clinical gastrointestinal motility as Director of the Swallowing and Motility Disorders services at the VA Boston Healthcare, and is involved with training and teaching of students, residents and fellows at Brigham and Women’s Hospital, the VA Boston Healthcare, and Harvard Medical School. He has published numerous original and review articles in various medical and scientific journals.

Other Positions

  • VA Boston Healthcare System



  • Albert Einstein College of Medicine, MD
  • Albert Einstein College of Medicine, PhD
  • Yeshiva University, MS
  • Harvard College, AB


  • Published on 10/17/2019

    Spechler SJ, Hunter JG, Jones KM, Lee R, Smith BR, Mashimo H, Sanchez VM, Dunbar KB, Pham TH, Murthy UK, Kim T, Jackson CS, Wallen JM, von Rosenvinge EC, Pearl JP, Laine L, Kim AW, Kaz AM, Tatum RP, Gellad ZF, Lagoo-Deenadayalan S, Rubenstein JH, Ghaferi AA, Lo WK, Fernando RS, Chan BS, Paski SC, Provenzale D, Castell DO, Lieberman D, Souza RF, Chey WD, Warren SR, Davis-Karim A, Melton SD, Genta RM, Serpi T, Biswas K, Huang GD. Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn. N Engl J Med. 2019 10 17; 381(16):1513-1523. PMID: 31618539.

    Read at: PubMed
  • Published on 4/28/2019

    Ahsen OO, Liang K, Lee HC, Wang Z, Fujimoto JG, Mashimo H. Assessment of chronic radiation proctopathy and radiofrequency ablation treatment follow-up with optical coherence tomography angiography: A pilot study. World J Gastroenterol. 2019 Apr 28; 25(16):1997-2009. PMID: 31086467.

    Read at: PubMed
  • Published on 2/10/2019

    Goyal RK, Guo Y, Mashimo H. Advances in the physiology of gastric emptying. Neurogastroenterol Motil. 2019 04; 31(4):e13546. PMID: 30740834.

    Read at: PubMed
  • Published on 10/9/2018

    Mkarimi M, Mashimo H. Advanced Imaging for Barrett's Esophagus and Early Neoplasia: Surface and Subsurface Imaging for Diagnosis and Management. Curr Gastroenterol Rep. 2018 Oct 09; 20(12):54. PMID: 30302571.

    Read at: PubMed
  • Published on 9/27/2018

    Ahsen OO, Liang K, Lee HC, Giacomelli MG, Wang Z, Potsaid B, Figueiredo M, Huang Q, Jayaraman V, Fujimoto JG, Mashimo H. Assessment of Barrett's esophagus and dysplasia with ultrahigh-speed volumetric en face and cross-sectional optical coherence tomography. Endoscopy. 2019 04; 51(4):355-359. PMID: 30261534.

    Read at: PubMed
  • Published on 7/5/2018

    Inadomi J, Alastal H, Bonavina L, Gross S, Hunt RH, Mashimo H, di Pietro M, Rhee H, Shah M, Tolone S, Wang DH, Xie SH. Recent advances in Barrett's esophagus. Ann N Y Acad Sci. 2018 12; 1434(1):227-238. PMID: 29974975.

    Read at: PubMed
  • Published on 5/25/2018

    Huang Q, Cheng Y, Chen L, Mingzhan D, Wang Y, Xu G, Shi J, Fan X, Zhou X, Zhang Y, Guo L, Liu T, Zhou D, Mashimo H, Gold JS, Zou X. Low risk of lymph node metastasis in 495 early gastric cardiac carcinomas: a multicenter clinicopathologic study of 2101 radical gastrectomies for early gastric carcinoma. Mod Pathol. 2018 10; 31(10):1599-1607. PMID: 29802360.

    Read at: PubMed
  • Published on 1/20/2018

    Liang K, Wang Z, Ahsen OO, Lee HC, Potsaid BM, Jayaraman V, Cable A, Mashimo H, Li X, Fujimoto JG. Cycloid scanning for wide field optical coherence tomography endomicroscopy and angiography in vivo. Optica. 2018 Jan 20; 5(1):36-43. PMID: 29682598.

    Read at: PubMed
  • Published on 12/1/2017

    Tsai TH, Leggett CL, Trindade AJ, Sethi A, Swager AF, Joshi V, Bergman JJ, Mashimo H, Nishioka NS, Namati E. Optical coherence tomography in gastroenterology: a review and future outlook. J Biomed Opt. 2017 Dec; 22(12):1-17. PMID: 29260538.

    Read at: PubMed
  • Published on 11/21/2017

    Ahsen OO, Lee HC, Liang K, Wang Z, Figueiredo M, Huang Q, Potsaid B, Jayaraman V, Fujimoto JG, Mashimo H. Ultrahigh-speed endoscopic optical coherence tomography and angiography enables delineation of lateral margins of endoscopic mucosal resection: a case report. Therap Adv Gastroenterol. 2017 Dec; 10(12):931-936. PMID: 29204188.

    Read at: PubMed

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